Mitoguazone
- CAS No.
- 459-86-9
- Chemical Name:
- Mitoguazone
- Synonyms
- MGBG;Me-GAG;methyl-g;methyl-gag;Mitoguazone USP/EP/BP;Mitoguazone(Methyl-GAG);Methylglycoxali BisguanylhydrazonuM;Pyruvaldehyde bis(amidinohydrazone);1,1'-((methylethanediylidene)dinitrilo)diguanidine;1,1'-((methylethanediylidene)dinitrilo)di-guanidin
- CBNumber:
- CB01179220
- Molecular Formula:
- C5H12N8
- Molecular Weight:
- 184.2
- MDL Number:
- MFCD00067519
- MOL File:
- 459-86-9.mol
- MSDS File:
- SDS
| Melting point | 225 °C (decomp) |
|---|---|
| Boiling point | 323.8±25.0 °C(Predicted) |
| Density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| pka | 7.63, 9.05(at 25℃) |
| form | Solid |
| color | Light brown to brown |
| Water Solubility | Water: 50 mg/mL (271.44 mM; ultrasonic and adjust pH to 9 with HCl) |
| CAS DataBase Reference | 459-86-9 |
| FDA UNII | OD5Q0L447W |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
Mitoguazone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M373450 | Mitoguazone | 459-86-9 | 100mg | $130 | 2021-12-16 | Buy |
| ChemScene | CS-0026193 | Mitoguazone 99.38% | 459-86-9 | 5mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-0026193 | Mitoguazone 99.38% | 459-86-9 | 10mg | $220 | 2021-12-16 | Buy |
| ChemScene | CS-0026193 | Mitoguazone 99.38% | 459-86-9 | 50mg | $610 | 2021-12-16 | Buy |
Mitoguazone Chemical Properties,Uses,Production
Uses
Mitoguazone has therapeutic applications as a cytotoxic agent.
Definition
ChEBI: A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine.
in vivo
The influence of different stages of leukemia P388 on the pharmacokinetics of the antineoplastic agent Mitoguazone in mice is investigated. Independent of the tumor stage investigated, the total clearance of mitoguazone is slightly reduced reflecting a moderate increase of AUC in the serum of leukemia-bearing animals. Furthermore, in an advanced tumor stage the drug levels in kidneys, liver, spleen and serum are found to be elevated to some extent in comparison to tumor-free controls in contrast to an earlier stage of leukemia[5].
Mitoguazone Preparation Products And Raw materials
Raw materials
Preparation Products
Mitoguazone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5854 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22854 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 2998 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 +86-15350571055 | Sibel@chuanghaibio.com | China | 6086 | 58 |
View Lastest Price from Mitoguazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-23 | Mitoguazone
459-86-9
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-03-07 | Mitoguazone
459-86-9
|
US $300.00-280.00 / kg | 1kg | 99.5%(HPLC) | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2021-07-03 | Mitoguazone USP/EP/BP | US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Mitoguazone
459-86-9
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Mitoguazone
459-86-9
- US $300.00-280.00 / kg
- 99.5%(HPLC)
- Hebei Yanxi Chemical Co., Ltd.
-
- Mitoguazone USP/EP/BP
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited