ChemicalBook >> CAS DataBase List >>Formoterol fumarate dihydrate
Formoterol fumarate dihydrate
- CAS No.
- 183814-30-4
- Chemical Name:
- Formoterol fumarate dihydrate
- Synonyms
- Formoterol fumarate dihydrate;Unii-W34shf8J2k;Formoterol hemifumar;forMaMide fuMarate dihydrate;Formoterol Fumarate (100 mg);Formoterol fumarate 2-hydrate;Arformoterol Fumarate Dihydrate;Formoterol Hemifumarate Dihydrate;Formoterol hemifumarate monohydrate;Formoterol fumarate dihydrate, >=99%
- CBNumber:
- CB02130563
- Molecular Formula:
- C23H28N2O8
- Molecular Weight:
- 460.48
- MDL Number:
- MFCD11045919
- MOL File:
- 183814-30-4.mol
- MSDS File:
- SDS
Last updated:2024-04-15 18:41:30
| Melting point | 116-120°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL |
| form | solid |
| color | white to off-white |
| InChIKey | RATSWNOMCHFQGJ-XODSYJLDSA-N |
| SMILES | C(/C(=O)O)=C\C(=O)O.[C@@H](C1C=CC(O)=C(NC=O)C=1)(O)CN[C@@H](C)CC1C=CC(OC)=CC=1 |&1:8,22,r| |
| CAS DataBase Reference | 183814-30-4 |
| FDA UNII | W34SHF8J2K |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H332-H361d-H370-H373-H412 |
| Precautionary statements | P201-P202-P260-P273-P304+P340+P312-P308+P311 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | 3 |
| HS Code | 29242990 |
Formoterol fumarate dihydrate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F9552 | Formoterol fumarate dihydrate >98% (HPLC) | 183814-30-4 | 10mg | $221 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2703 | Formoterol fumarate PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial,certifiedrefer | 183814-30-4 | 500MG | $400 | 2024-03-01 | Buy |
| Sigma-Aldrich | F0372000 | Formoterol fumarate dihydrate European Pharmacopoeia (EP) Reference Standard | 183814-30-4 | 10mg | $181 | 2022-05-15 | Buy |
| Sigma-Aldrich | F9552 | Formoterol fumarate dihydrate >98% (HPLC) | 183814-30-4 | 50mg | $761 | 2024-03-01 | Buy |
| Sigma-Aldrich | F0372000 | Formoterol fumarate dihydrate European Pharmacopoeia (EP) Reference Standard | 183814-30-4 | f0372000 | $153 | 2024-03-01 | Buy |
Formoterol fumarate dihydrate Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
Formoterol is a selective β2-adrenergic receptor agonist. Formoterol is used as an antiasthmatic.
Uses
ForMoterol FuMarate Dihydrate is a selective β2-adrenergic receptor agonist,it is used as an antiasthmatic.
Biological Activity
Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.
Biochem/physiol Actions
β2-Adrenoreceptor agonist.
Drug interactions
The efficacy and tolerability of glycopyrronium/formoterol fumarate metered dose inhaler, a fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate 14.4/10 μg (equivalent to glycopyrrolate/formoterol fumarate 18/9.6 μg) delivered by metered dose inhaler using innovative co-suspension delivery technology, was investigated in patients (n = 292) with COPD [12C]. There were no meaningful pharmacokinetic interactions, whether drug–drug or due to formulation, between glycopyrronium and formoterol following treatment with formulated using a new co-suspension delivery technology. The incidence of cardiovascular events of special interest was low (stroke, 0%–0.4%; cardiac ischemia, 0.4%–2.3%; cardiac failure, 1.3%–2.5%; arrhythmia, 1.3%–3.2%), and no important trends in clinical laboratory results, vital signs, or electrocardiograms were observed[1].
References
[1] Aagaard, Lise . "A worldwide yearly survey of new data in adverse drug reactions." (2014).
Formoterol fumarate dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 211)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
| Shandong Risen-Sun Pharmaceutical Co., Ltd | +86-15552509998 +86-15621883869 | liutf@jewim.com.cn | China | 251 | 58 |
| Changzhou Rokechem Technology Co., Ltd. | 18758118018 | sales001@rokechem.com | China | 255 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18775 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
View Lastest Price from Formoterol fumarate dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-27 | Formoterol Fumarate Monohydrate/ dihydrate
183814-30-4
|
US $0.00 / g/Bag | 10g | 98.5%min; JP14 | 20kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-09-25 | Formoterol Fumarate Dihydrate
183814-30-4
|
US $0.00 / KG | 1KG | 99% | 20 TONS | Wuhan Senwayer Century Chemical Co.,Ltd | |
![(R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate pictures](/ProductImageEN/2023-11/Small/568bf98e-ab0a-431c-8c3e-82b471ec1778.jpg) |
2024-08-27 | (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate
183814-30-4
|
US $65.00-650.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd |
-
- Formoterol Fumarate Monohydrate/ dihydrate
183814-30-4
- US $0.00 / g/Bag
- 98.5%min; JP14
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Formoterol Fumarate Dihydrate
183814-30-4
- US $0.00 / KG
- 99%
- Wuhan Senwayer Century Chemical Co.,Ltd
-
- (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate
183814-30-4
- US $65.00-650.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
183814-30-4(Formoterol fumarate dihydrate)Related Search:
Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, rel-, (2E)-2-butenedioate (2:1) (salt), dihydrate
Unii-W34shf8J2k
(±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate
Formoterol fumarate dihydrate ,98.5%
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Formoterol Fumarate (100 mg)
forMaMide fuMarate dihydrate
N-(2-hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide fuMarate dihydrate
Formoterol fumarate dihydrate, >=99%
(R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrateChemicalBook
R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate
Formoterol hemifumarate monohydrate
Formoterol fumarate dihydrate Solution in Methanol, 100μg/mL
Formoterol Fumarate Monohydrate/ dihydrate
Formoterol hemifumar
Formoterol fumarate dihydrateQ: What is
Formoterol fumarate dihydrate Q: What is the CAS Number of
Formoterol fumarate dihydrate Q: What is the storage condition of
Formoterol fumarate dihydrate
Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate
Formoterol fumarate dihydrate
Formoterol fumarate 2-hydrate
Formoterol hemifumarate
salt monohydrate
Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate
Arformoterol Fumarate Dihydrate
Formoterol Hemifumarate Dihydrate
C13919000 FormoteroLfumaratEdihydrate
183814-30-4
183818-30-4
C19H24N2O4189C4H4O4
C23H32N2O10
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