ChemicalBook >> CAS DataBase List >>Pamoic acid disodium salt
Pamoic acid disodium salt
- CAS No.
- 6640-22-8
- Chemical Name:
- Pamoic acid disodium salt
- Synonyms
- PAMOIC ACID NA;sodium pamoate;DISODIUMEMBONATE;DisodiumPamoate98%;PAMOIC ACID DISODIUM;Cyprofuram Impurity 1;PAMOIC ACID DISODIUM SALT;EMBONIC ACID DISODIUM SALT;PAMOIC ACID DISODIUM SALT 98%;PAMOIC ACID DISODIUM SALT 98+%
- CBNumber:
- CB0247382
- Molecular Formula:
- C23H17NaO6
- Molecular Weight:
- 412.37
- MDL Number:
- MFCD00036183
- MOL File:
- 6640-22-8.mol
Last updated:2025-04-17 18:22:24
| Melting point | 300 °C |
|---|---|
| Density | 1.55[at 20℃] |
| vapor pressure | 0.001Pa at 25℃ |
| storage temp. | Desiccate at RT |
| solubility | insoluble in EtOH; ≥18 mg/mL in H2O; ≥28.6 mg/mL in DMSO |
| form | solid |
| color | Pale yellow |
| Water Solubility | 43g/L at 20℃ |
| LogP | -3.2 at 20℃ |
| CAS DataBase Reference | 6640-22-8(CAS DataBase Reference) |
| FDA UNII | RPO7LTE47E |
| EPA Substance Registry System | 2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt (6640-22-8) |
| UNSPSC Code | 12352106 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-37/38-41-48 | |||||||||
| Safety Statements | 24/25-45-36/37/39-26-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2918.29.7500 | |||||||||
| NFPA 704 |
|
Pamoic acid disodium salt price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P5022 | Pamoic acid disodium salt | 6640-22-8 | 25g | $101 | 2024-03-01 | Buy |
| TCI Chemical | P1059 | Pamoic Acid Disodium Salt Monohydrate >98.0%(HPLC) | 6640-22-8 | 25g | $61 | 2024-03-01 | Buy |
| TCI Chemical | P1059 | Pamoic Acid Disodium Salt Monohydrate >98.0%(HPLC) | 6640-22-8 | 250g | $295 | 2024-03-01 | Buy |
| Tocris | 4298 | Pamoic acid disodium salt ≥99%(HPLC) | 6640-22-8 | 50 | $101 | 2021-12-16 | Buy |
| TRC | P173503 | Pamoic acid disodium salt | 6640-22-8 | 50mg | $100 | 2021-12-16 | Buy |
Pamoic acid disodium salt Chemical Properties,Uses,Production
Chemical Properties
pale yellow to yellow powder
Uses
Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer.
Flammability and Explosibility
Not classified
Biological Activity
Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.
in vivo
Pamoic acid disodium (0-100 mg/kg; s.c.; once) induces a dose-related antinociception in the abdominal constriction test[1].
| Animal Model: | Swiss-Webster mice (30–35 g)[1] |
| Dosage: | 25, 50, and 100 mg/kg |
| Administration: | Subcutaneous injection, once |
| Result: | Elicited dose-related antinociception, the dose causing 50% antinociception being 40.5 mg/kg. |
Pamoic acid disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 186)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19805 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 | wucy@ribio.com.cn | China | 117 | 58 |
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | yunbiochem@126.com | China | 321 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32202 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10244 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from Pamoic acid disodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-15 | Pamoic acid disodium
6640-22-8
|
US $358.00 / g | 10g | TargetMol Chemicals Inc. | |||
 |
2021-08-12 | 4,4"-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt
6640-22-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-02 | Pamoic Acid Disodium Salt Monohydrate
6640-22-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Pamoic acid disodium
6640-22-8
- US $358.00 / g
- TargetMol Chemicals Inc.
-
- 4,4"-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt
6640-22-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Pamoic Acid Disodium Salt Monohydrate
6640-22-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
6640-22-8(Pamoic acid disodium salt)Related Search:
Sodium Phosphate, Dibasic
Sodium phosphate dibasic dodecahydrate
Pamoic acid
1,1'-METHYLENEDI-2-NAPHTHOL
2,2'-METHYLENEDIPHENOL
2-Naphthoic acid
Sodium diacetate
2-Naphthalenemethanol
3-Hydroxy-2-naphthoic acid
Sodium salicylate
1of4
PAMOIC ACID DISODIUM SALT 98+%
DisodiumPamoate98%
DISODIUMEMBONATE
4,4μ-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid, Sodium pamoate
2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt
Disodium 4-[(3-carboxylato-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate
1,1'-Methylenebis(2-hydroxy-3-naphthalenecarboxylic acid sodium) salt
1,1'-Methylenebis(2-hydroxy-3-naphthalenecarboxylic acid)disodium salt
Embonic Acid Disodium Salt
4,4'-Methylenebis(3-hydroxy-2-naphthoic Acid Sodium Salt)
PaMoic Acid DisodiuM Salt
2-Naphthalenecarboxylicacid, 4,4'-Methylenebis[3-hydroxy-, sodiuM salt (1:2)
Pamoic acid disodium salt hydrate
Sodium 4,4'-methylenebis(3-hydroxy-2-naphthoate)
EMBONIC ACID DISODIUM SALT
PAMOIC ACID DISODIUM SALT
PAMOIC ACID NA
sodium pamoate
4,4'-METHYLENEBIS(3-HYDROXY-2-NAPHTHOIC ACID SODIUM SALT)
2,2'-DIHYDROXY-1,1'-DINAPHTHYLMETHANE-3,3'-DICARBOXYLIC ACID DISODIUM SALT
1,1'-METHYLENE-BIS[2-HYDROXY-3-NAPHTHOIC ACID] DISODIUM SALT
disodium 4,4'-methylenebis[3-hydroxy-2-naphthoate]
PAMOIC ACID DISODIUM
PAMOIC ACID DISODIUM SALT 98%
4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) disodium salt
PamoicAcidDisodiumSaltMonohydrate>
isodium,3-carboxy-1-[(3-carboxy-2-oxidonaphthalen-1-yl)methyl]naphthalen-2-olate
4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt
3-carboxy-1-[(3-carboxy-2-oxidonaphthalen-1-yl)methyl]naphthalen-2-olate
Cyprofuram Impurity 1
Disodium 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate)
Disodium 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate)
6640-22-8
C23H14Na2O6
C23H14O6Na2
C23H16O62Na
C23H14Na2O6H2O
C23H16O6Na
C23H16Na2O6
C23H14O62Na