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ChemicalBook >> CAS DataBase List >>1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Structure
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine structure
CAS No.
681482-80-4
Chemical Name:
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine
Synonyms
1-[4-(oxan-2-yloxy)phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine;1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine;Piperidine, 1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]-
CBNumber:
CB03154168
Molecular Formula:
C23H26F3NO4
Molecular Weight:
437.45
MDL Number:
MOL File:
681482-80-4.mol
Last updated:2023-06-04 08:28:37
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1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Properties

Boiling point 530.2±50.0 °C(Predicted)
Density 1.252±0.06 g/cm3(Predicted)
solubility soluble in Chloroform, DCM
pka 3.84±0.20(Predicted)
form Solid
color Off-White

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T295040 1-[4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine 681482-80-4 5mg $140 2021-12-16 Buy
Medical Isotopes, Inc. 48873 1-[4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine 681482-80-4 5mg $625 2021-12-16 Buy
Product number Packaging Price Buy
T295040 5mg $140 Buy
48873 5mg $625 Buy

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Chemical Properties,Uses,Production

Uses

1-[4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine synthesis

36603-49-3
287952-67-4
681482-80-4
Synthesis of 1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine from 2-(4-BROMOPHENOXY)TETRAHYDRO-2H-PYRAN and 4-[4-(TRIFLUOROMETHOXY)PHENOXY]PIPERIDINE

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Preparation Products And Raw materials

Raw materials

4-[4-(TRIFLUOROMETHOXY)PHENOXY]PIPERIDINE 2-(4-BROMOPHENOXY)TETRAHYDRO-2H-PYRAN

Preparation Products

1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20035 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016 3287908757@qq.com China 9118 58
Supplier Advantage
Lynnchem 58
Novachemistry 58
Suzhou Meishi Biotechnology Co., Ltd. 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 58
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine 1-[4-(oxan-2-yloxy)phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine Piperidine, 1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]- 681482-80-4