ChemicalBook >> CAS DataBase List >>FARNESYLPYROPHOSPHATE
FARNESYLPYROPHOSPHATE
- CAS No.
- 13058-04-3
- Chemical Name:
- FARNESYLPYROPHOSPHATE
- Synonyms
- FPP;trans, trans-farnesyl diphosphate;FARNESYL PYROPHOSPHATE AMMONIUM SALT;FPP 3NH3;FPP 3NH4;FARNESYL-PP;FARNESYLDIPHOSPHATE;FARNESYLPYROPHOSPHATE;FARNESYL DIPHOSPHATE-TA;(E,E)-farnesyl diphosphate
- CBNumber:
- CB0378488
- Molecular Formula:
- C15H28O7P2
- Molecular Weight:
- 382.33
- MDL Number:
- MFCD00189688
- MOL File:
- 13058-04-3.mol
Last updated:2023-05-04 17:34:32
| Melting point | >107°C (dec.) |
|---|---|
| Boiling point | 533.8±60.0 °C(Predicted) |
| Density | 1.233±0.06 g/cm3(Predicted) |
| Flash point | 11 °C |
| storage temp. | -20°C |
| solubility | Methanol (Slightly, Sonicated), Water (Slightly) |
| form | methanol:ammonia solution |
| pka | 1.07±0.50(Predicted) |
| color | White to Brown |
| Stability | Hygroscopic, Light Sensitive, Temperature Sensitive |
| FDA UNII | 79W6B01D07 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H301+H311+H331-H315-H319-H370 |
| Precautionary statements | P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN 1230 3/PG 2 |
| WGK Germany | 1 |
FARNESYLPYROPHOSPHATE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F6892 | Farnesyl pyrophosphate ammonium salt methanol:ammonia solution, ≥95% (TLC) | 13058-04-3 | 1vial | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | F6892 | Farnesyl pyrophosphate ammonium salt methanol:ammonia solution, ≥95% (TLC) | 13058-04-3 | 5vials | $363 | 2024-03-01 | Buy |
| Usbiological | 276173 | Farnesyl pyrophosphate triammonium salt | 13058-04-3 | 1mg | $698 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BIO0000460 | FARNESYL PYROPHOSPHATE AMMONIUM SALT 95.00% | 13058-04-3 | 5MG | $501.48 | 2021-12-16 | Buy |
FARNESYLPYROPHOSPHATE Chemical Properties,Uses,Production
Uses
Farnesyl pyrophosphate ammonium salt has been used:
- as a prenylation agonist in human osteogenic sarcoma cells in collagen-based cell invasion assays
- in the prenylation of the hepatocyte growth factor (HGF) in human umbilical vein endothelial cells (HUVECs)
- as a substrate in prenyltransferases assay in diatom Haslea ostrearia
Definition
ChEBI: 2-trans,6-trans-farnesyl diphosphate is the trans,trans-stereoisomer of farnesyl diphosphate. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a 2-trans,6-trans-farnesyl diphosphate(3-).
General Description
Farnesyl pyrophosphate is a 15-carbon isoprenoid synthesized from geranyl pyrophosphate (GPP) by the action of enzyme farnesyl pyrophosphate synthase (FPPS).
Biochem/physiol Actions
Farnesyl pyrophosphate (FPP) is the precursor for the biosynthesis of cholesterol, ubiquinone and dolicol. It is part of the intracellular mevalonate pathway. FPP is essential for cell survival and is used for prenylation of several low molecular mass G proteins, including Ras. Inhibition of prenylation results in loss of oncogenic potential of Ras proteins. Inhibition of prenylation may serve as therapeutic potential for management of synaptic plasticity and Alzheimer′s disease.
Purification Methods
Purify the pyrophosphate by chromatography on Whatman No3 MM paper in a system of isopropanol-isobutanol/ammonia/water (40:20:1:30) (v/v). Store it as the Li or NH4 salt at 0o. See geranylgeranyl pyrophosphate below.
FARNESYLPYROPHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
FARNESYLPYROPHOSPHATE Suppliers
Global( 43)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 16166 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Shanghai Baoyisheng Biotechnology Co., LTD | 15221020695 | 502277408@qq.com | China | 478 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57412 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Hubei yongkuo Technology Co., Ltd | 027-59223108 15972152991 | 1248580099@qq.com | China | 9988 | 58 |
| Hubei Xinkang Pharmaceutical Chemical Co., Ltd | 027-59308705 18871579363 | 1248180077@qq.com | China | 9949 | 58 |
| Anqing Rong Chuang Biological Technology Co., Ltd. | 15001988657 | 1367753897@qq.com | China | 989 | 58 |
13058-04-3(FARNESYLPYROPHOSPHATE)Related Search:
farnesylpyrophosphate cyclase
FARNESYLPYROPHOSPHATE
OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT
OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT, [1-3H]
Geranylgeranyl pyrophosphate
1of3
FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT SOLUTION
FPP, 3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt
(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-triene-1-ol diphosphoric acid
(E,E)-Farnesyl pyrophosphate
3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE
3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE 3NH3
3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE AMMONIUM SALT
FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT
FARNESYLPYROPHOSPHATE
FARNESYL DIPHOSPHATE-TA
FPP 3NH3
FPP 3NH4
Diphosphoric acid α-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester
(E,E)-farnesyl diphosphate
2-trans,6-trans-farnesyl diphosphate
all-trans-farnesyl diphosphate
FARNESYL-PP
Farnesyl pyrophosphate ammonium salt, in ethanol
FARNESYL PYROPHOSPHATE AMMONIUM 200
TRANS, TRANS FARNESYL PYROPHOSPHATE TRIAMMONIUM SALT
3,7,11-trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt
[hydroxy-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]phosphoryl]oxyphosphonic acid
FARNESYLDIPHOSPHATE
farnesyl pyrophosphate ammonium*200 ug/vial
Diphosphoric acid, P-(3,7,11-trimethyl-2,6,10-dodecatrien-1-yl) ester
Farnesyl pyrophosphate ammonium salt methanol:ammonia solution
FARNESYL PYROPHOSPHATE AMMONIUM SALT
FPP
trans, trans-farnesyl diphosphate
3,7,11-Trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate
13058-04-3
C15H28O7P2
C15H37N3O7P2
Post-translational Modification
Cell Signaling and Neuroscience
Cell Biology
BioChemical
G Protein Function
G Proteins and Cyclic Nucleotides