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Taxifolin

Taxifolin Structure
Taxifolin structure
CAS No.
480-18-2
Chemical Name:
Taxifolin
Synonyms
DIHYDROQUERCETIN;distylin;taxifoliol;Larch extract;(+)-TAXIFOLIN;(2R,3R)-(+)-Taxifolin;(2R,3R)-DIHYDROQUERCETIN;Taxifolin (Dihydroquercetin);CPD-474;Lavitol
CBNumber:
CB0402424
Molecular Formula:
C15H12O7
Molecular Weight:
304.25
MDL Number:
MFCD00006845
MOL File:
480-18-2.mol
Last updated:2024-11-27 19:59:28
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Taxifolin Properties

Melting point 230-233°C (dec.)
Boiling point 365.09°C (rough estimate)
Density 1.3326 (rough estimate)
refractive index 1.4790 (estimate)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 7.39±0.60(Predicted)
color White to Yellow
BRN 5299277
InChI InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
InChIKey CXQWRCVTCMQVQX-LSDHHAIUSA-N
SMILES [C@H]1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP 0.950
CAS DataBase Reference 480-18-2(CAS DataBase Reference)
FDA UNII 9SOB9E3987
EPA Substance Registry System 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- (480-18-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  LK6920000
HazardClass  IRRITANT
HS Code  29329990
NFPA 704
0
2 0

Taxifolin price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 78666 Taxifolin analytical standard 480-18-2 25mg $75.7 2024-03-01 Buy
Sigma-Aldrich 78666 Taxifolin analytical standard 480-18-2 100mg $254 2024-03-01 Buy
Sigma-Aldrich 03890585 Taxifolin primary reference standard 480-18-2 10mg $330 2023-06-20 Buy
TCI Chemical T3666 (+)-Taxifolin 480-18-2 200MG $114 2024-03-01 Buy
TCI Chemical T3666 (+)-Taxifolin 480-18-2 1G $344 2024-03-01 Buy
Product number Packaging Price Buy
78666 25mg $75.7 Buy
78666 100mg $254 Buy
03890585 10mg $330 Buy
T3666 200MG $114 Buy
T3666 1G $344 Buy

Taxifolin Chemical Properties,Uses,Production

Structural chemistry

Taxifolin is a subclass of flavanonols, an isoflavanone in flavonoids family. The basic structure of two phenyl groups (ring A and ring B) which are joined together by a heterocyclic ring referred to as ring C . The structure contains 3-hydroxyl group at the C ring which is connected to the B ring at carbon-2. Taxifolin is a pentahydroxyflavone containing five hydroxyl groups at the 3-, 3'-, 4'-, 5- and 7-positions. It  has two stereocenters on the C-ring and 4 stereoisomers. It with the configuration of (2R, 3R) is one of them and it comprises 2 pairs of enantiomers.

Description

Taxifolin, a chemical substance extracted from pine plants such as larch and Douglas fir. It belongs to the bioflavonoid pseudo-vitamin P, and its scientific name is dihydroquercetin. Japanese scholar Fukui first isolated it from the leaves of conifers (Chamaecyparis obtusa), and its biological activity was subsequently discovered and confirmed.

Chemical Properties

Yellow Solid

Uses

An antioxidant flavenoid.

Uses

(+)-Taxifolin is a flavanon compound which modulates chemopreventive genes.

Uses

Reference Standard in the analysis of herbal medicinal products

Application

Taxifolin is a flavonoid commonly found in onion, milk, French maritime pine bark and Douglas fir bark. It is also used in various commercial preparations like Legalon?, Pycnogenol?, and Venoruton?. This review focuses on taxifolin’s biological activities and related molecular mechanisms. It showed promising pharmacological activities in the management of inflammation, tumors, microbial infections, oxidative stress, cardiovascular, and liver disorders. The anti-cancer activity was more prominent than other activities evaluated using different in vitro and in vivo models. Further research on the pharmacokinetics, in-depth molecular mechanisms, and safety profile using well-designed randomized clinical studies are suggested to develop a drug for human use.

Definition

ChEBI: A taxifolin that has (2R,3R)-configuration.

General Description

Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae.

Taxifolin Preparation Products And Raw materials

Raw materials

Preparation Products

LEUCOCYANIDIN POLYMER

Taxifolin Suppliers

Global( 448)Suppliers
Supplier Tel Email Country ProdList Advantage
Hovane Phytochemicals Co., Ltd 		+86-17340288373 victor.liu@hovane.com China 32 58
Wuhan Haorong Biotechnology Co.,ltd
+86-18565342920; +8618565342920 sales@chembj.net China 289 58
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12839 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5892 58
Hebei Kingfiner Technology Development Co.Ltd 		+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3010 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618092446649 sarah@tnjone.com China 1143 58
BINBO BIOLOGICAL CO.,LTD 		+8618629063126 info@binbobiological.com China 390 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd. 		+8615373025980 clara@hbshengyang.com China 874 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Supplier Advantage
Hovane Phytochemicals Co., Ltd 		58
Wuhan Haorong Biotechnology Co.,ltd
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Kingfiner Technology Development Co.Ltd 		58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		58
BINBO BIOLOGICAL CO.,LTD 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Hebei Shengyang Water Conservancy Engineering Co., Ltd. 		58
Henan Tianfu Chemical Co.,Ltd. 		55

Related articles

View Lastest Price from Taxifolin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Taxifolin pictures 2024-11-28 Taxifolin
480-18-2
 US $0.00 / kg 1kg 98% 1000 kg BINBO BIOLOGICAL CO.,LTD
Taxifolin pictures 2024-11-28 Taxifolin
480-18-2
 US $45.00 / kg 1kg 99% 5000kg/Week Hebei Zhuanglai Chemical Trading Co.,Ltd
Taxifolin pictures 2024-11-28 Taxifolin
480-18-2
 US $0.00-0.00 / kg 1kg 1-98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
  • Taxifolin pictures
  • Taxifolin
    480-18-2
  • US $0.00 / kg
  • 98%
  • BINBO BIOLOGICAL CO.,LTD
  • Taxifolin pictures
  • Taxifolin
    480-18-2
  • US $45.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
  • Taxifolin pictures
  • Taxifolin
    480-18-2
  • US $0.00-0.00 / kg
  • 1-98%
  • Changsha Staherb Natural Ingredients Co., Ltd.

Taxifolin Spectrum

Taxifolin(480-18-2)1HNMR

480-18-2(Taxifolin)Related Search:

Pinostrobin Quercetin dihydrate Paclitaxel Docetaxel PLUMBAGIN
CASTICIN Chrysophanic acid Hypericin Oleanolic acid LYSIONOTIN
TAXIFOLIN 3-O-RHAMNOSIDE alpha-Dihydroartemisinin Eurycoma longifolia powder extract Perilla oil Pterostilbene
Quercetin 3,3',4',5',7-PENTAHYDROXYFLAVANONE (+)-3,3',4',5,7-PENTAHYDROXYFLAVANONE,3,3',4',5,7-PENTAHYDROXYFLAVANONE,3,5,7,3',4'-PENTAHYDROXYFLAVANONE

1of4

2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-on 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-on( 2,3-dihydro-3,3’,4’,5,7-pentahydroxy-flavon 2theta-trans)- 3,3’,4’,5,7-pentahydroxy-flavanon dihydro-querceti TAXIFOLIN(P) TAXIFOLIN, (+)-(RG) (2R-trans)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4-benzopyrone Dihydroquercetin,~99% TAXIFOLIN SNAP-N-SHOOT 0.1mg/mL(P) (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (+)-Taxifolin ,98% (+)-trans Taxifolin 2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)- 2-(3,4,5-Trihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-4H-1-benzopyran-4-one (3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro taxifolin or dihydroquercetin CPD-474 trans dihydroquercetin (2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone (2R,3R)-Dihydroquercetin (2R,3R)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-1-benzopyran-4-one Diquertin Lariksin Lavitol (+)-3,3',4',5,7-PENTAHYDROXYFLAVANONE 3,3',4',5,7-PENTAHYDROXYFLAVANONE (2R,3R)-3,3',4',5,7-PENTAHYDROXYFLAVANONE 3,5,7,3',4'-PENTAHYDROXYFLAVANONE (+)-DIHYDROQUERCETIN TAXIFOLIN TAXIFOLIN, (+)- Taxifoliol,Distylin 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroMan-4-one Taxifolin SynonyMs (2R,3R)-3,3',4',5,7-Pentahydroxyflavanone 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- (2S,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-chromanone 3,3',4',5,7-Pentahydroxydihydroflavone 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R-trans)- FLAVANONE, 3,3',4',5',7-PENTAHYDROXY (2R,3R)-2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-oxo-3,4-dihydro-2H-1-benzopyran-5-olate Taxifolin，TAX Taxifolin USP/EP/BP (+)-(2R,3R)-Dihydroquercetin (+)-Dihydroquercetin Dihydroquercetin/Taxifolin (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one distylin (2R,3R)-(+)-Taxifolin DIHYDROQUERCETIN Taxifolin (Dihydroquercetin) Larch extract (2R,3R)-DIHYDROQUERCETIN (+)-TAXIFOLIN taxifoliol (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one