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TAXIFOLIN 3-O-RHAMNOSIDE

TAXIFOLIN 3-O-RHAMNOSIDE structure

CAS No.: 29838-67-3

Chemical Name:: TAXIFOLIN 3-O-RHAMNOSIDE

Synonyms: Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Astilbin-RM;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin froM Engelhardtia roxburghiana

CBNumber:: CB7507018

Molecular Formula:: C21H22O11

Molecular Weight:: 450.4

MDL Number:: MFCD20274680

MOL File:: 29838-67-3.mol

MSDS File:: SDS

Last updated:2024-12-11 16:58:07

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TAXIFOLIN 3-O-RHAMNOSIDE Properties

Melting point	180 °C (decomp)
Boiling point	801.1±65.0 °C(Predicted)
Density	1.74
storage temp.	Sealed in dry,2-8°C
solubility	H2O: soluble1mg/mL, clear, colorless
pka	7.34±0.60(Predicted)
form	A crystalline solid
color	White to off-white
InChIKey	ZROGCCBNZBKLEL-MQGABXIONA-N
SMILES	O([C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@H]1C(C2=C(C=C(O)C=C2O[C@@H]1C1C=CC(O)=C(O)C=1)O)=O \|&1:1,4,6,8,10,12,22,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H400
Precautionary statements	P273
Hazard Codes	N
Risk Statements	50
Safety Statements	61
RIDADR	UN 3077 9 / PGIII
WGK Germany	3
HS Code	29389090

TAXIFOLIN 3-O-RHAMNOSIDE price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A2862	Astilbin from Engelhardtia roxburghiana ≥98%	29838-67-3	10mg	$199	2024-03-01	Buy
Cayman Chemical	28267	Astilbin	29838-67-3	10mg	$109	2024-03-01	Buy
Cayman Chemical	28267	Astilbin	29838-67-3	100mg	$537	2024-03-01	Buy
Cayman Chemical	28267	Astilbin	29838-67-3	5mg	$62	2024-03-01	Buy
Cayman Chemical	28267	Astilbin	29838-67-3	25mg	$239	2024-03-01	Buy

Product number	Packaging	Price	Buy
A2862	10mg	$199	Buy
28267	10mg	$109	Buy
28267	100mg	$537	Buy
28267	5mg	$62	Buy
28267	25mg	$239	Buy

TAXIFOLIN 3-O-RHAMNOSIDE Chemical Properties,Uses,Production

Description

Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC₅₀s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.

Uses

Astilbin displays anti-depressant activity involving monoaminergic neurotransmitters an the BDNF signal pathway. Anti-oxidant.

Definition

ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.

TAXIFOLIN 3-O-RHAMNOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

TAXIFOLIN 3-O-RHAMNOSIDE Suppliers

Global( 230)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hovane Phytochemicals Co., Ltd	+86-17340288373	victor.liu@hovane.com	China	32	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	lisa@kingfinertech.com	China	3010	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883 +86-16264648883	niki@zlchemi.com	China	2691	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58

Supplier	Advantage
Hovane Phytochemicals Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Kingfiner Technology Development Co.Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from TAXIFOLIN 3-O-RHAMNOSIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-12-20	Astilbin 29838-67-3	US $150.00 / kg	1kg	99%	500kg	Hebei Zhuanglai Chemical Trading Co Ltd
2024-12-20	TAXIFOLIN 3-O-RHAMNOSIDE 29838-67-3	US $0.00-0.00 / kg	1kg	≥98% HPLC	1000kg	Changsha Staherb Natural Ingredients Co., Ltd.
2024-12-20	Astilbin 29838-67-3	US $0.00-0.00 / kg	1kg	80%HPLC	1 ton	Hovane Phytochemicals Co., Ltd

Astilbin
29838-67-3
US $150.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co Ltd

TAXIFOLIN 3-O-RHAMNOSIDE
29838-67-3
US $0.00-0.00 / kg
≥98% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

Astilbin
29838-67-3
US $0.00-0.00 / kg
80%HPLC
Hovane Phytochemicals Co., Ltd

TAXIFOLIN 3-O-RHAMNOSIDE Spectrum

TAXIFOLIN 3-O-RHAMNOSIDE(29838-67-3)IR1 TAXIFOLIN 3-O-RHAMNOSIDE(29838-67-3)IR2

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Forskolin SCUTELLAREIN CASTICIN Hydroxysafflor yellow A TAXIFOLIN 3-O-RHAMNOSIDE

PINOBANKSIN DIHYDROKAEMPFEROL (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one

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Taxifolin 3-o-rhamnoside Astilbin Taxifolin 3-O-rhaMnoside Taxifolin 3-rhaMnoside Astilbin froM Engelhardtia roxburghiana Dihydroquercetin 3-rhamnoside (2R,3R)-3-[(6-Deoxy-alpha-L-mannopyranosyloxy)]-2-(3,4-dihydroxy-phenyl)-2,3-dihydro-5,7-dihydroxy-4H-chromen-4-one (2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Astilbin, 98%, from Smilax glabra Roxb. 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2R,3R)- (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one (2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)chroman-4-one (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihy... Astilbin (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside Astilbin (6CI, 7CI, 8CI) Loastilin Astilbin-RM 29838-67-3 Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract