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TAXIFOLIN 3-O-RHAMNOSIDE

TAXIFOLIN 3-O-RHAMNOSIDE 구조식 이미지

카스 번호:: 29838-67-3

상품명:: TAXIFOLIN 3-O-RHAMNOSIDE

동의어(영문):: Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin froM Engelhardtia roxburghiana;Astilbin, 98%, from Smilax glabra Roxb.

CBNumber:: CB7507018

분자식:: C21H22O11

포뮬러 무게:: 450.4

MOL 파일:: 29838-67-3.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 226

TAXIFOLIN 3-O-RHAMNOSIDE 속성

녹는점: 180 °C (decomp)

끓는 점: 801.1±65.0 °C(Predicted)

밀도: 1.74

저장 조건: Sealed in dry,2-8°C

용해도: H2O: 용해성1mg/mL, 투명, 무색

산도 계수 (pKa): 7.34±0.60(Predicted)

물리적 상태: 결정성 고체

색상: White to off-white

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	N
위험 카페고리 넘버	50
안전지침서	61
유엔번호(UN No.)	UN 3077 9 / PGIII
WGK 독일	3
HS 번호	29389090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H400	수생생물에 매우 유독함	수생 환경유해성 물질 - 급성	구분 1	경고		P273, P391, P501

예방조치문구:

P273

환경으로 배출하지 마시오.

TAXIFOLIN 3-O-RHAMNOSIDE C화학적 특성, 용도, 생산

개요

Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC₅₀s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.

정의

ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.

TAXIFOLIN 3-O-RHAMNOSIDE 준비 용품 및 원자재

원자재

준비 용품

TAXIFOLIN 3-O-RHAMNOSIDE 공급 업체

글로벌( 226)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Guanlang Biotechnology Co,.LTD	+86-19930503253; +8619930503252	daisy@crovellbio.com	China	5831	58
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	lisa@kingfinertech.com	China	2989	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21669	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29897	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3777	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58

TAXIFOLIN 3-O-RHAMNOSIDE 관련 검색:

Swertiamarine Deacetyltaxol 7-EPI-10-DEACETYLTAXOL Cryptotanshinone Mogroside V PROCYANIDIN B2 Dioscin 7-Xylosyl-10-deacetyltaxol 7-Epitaxol Cephalomannine Forskolin SCUTELLAREIN CASTICIN Hydroxysafflor yellow A TAXIFOLIN 3-O-RHAMNOSIDE PINOBANKSIN DIHYDROKAEMPFEROL (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one