Forskolin
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Forskolin 속성
- 녹는점
- 282-232 °C
- 끓는 점
- 520℃
- 알파
- D25 -26.19° (c = 1.68 in CHCl3)
- 밀도
- 1.23
- 굴절률
- 1.5300 (estimate)
- 인화점
- 172℃
- 저장 조건
- room temp
- 용해도
- DMSO: 5mg/mL, 실온에서 최소 6개월간 안정함
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 11.00±0.70(Predicted)
- 색상
- 회백색
- 수용성
- 에탄올, 디메틸술폭시드 및 클로로포름에 용해됩니다. 물에 용해.
- 최대 파장(λmax)
- 305nm(lit.)
- Merck
- 14,2476
- BRN
- 1692716
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°에서 최대 4개월 동안 보관할 수 있습니다.
- InChIKey
- OHCQJHSOBUTRHG-KGGHGJDLSA-N
- LogP
- 2.406 (est)
- CAS 데이터베이스
- 66575-29-9
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Forskolin C화학적 특성, 용도, 생산
화학적 성질
Colorless Crystalline Solid용도
Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.일반 설명
Forskolin, present predominantly in the root of Coleus forskohlii plant, is a potential pharmacological compound. It is used for treating hypertension, respiratory disorders and obesity. Forskolin is a diterpenoid capable of modulating adenylate cyclase enzyme and cyclic adenosine monophosphate (cAMP) levels. Engineering forskolin biosynthetic pathway caters its commercial production for pharmacological use. Forskolin has antioxidant and anti-inflammatory property and reduces hyperglycemia by stimulating insulin release. Forskolin promotes differentiation of hepatoma HepaRG cells and activates farnesoid X receptor (FXR) and pregnane X receptor(PXR).생물학적 활성
Cell-permeable activator of adenylyl cyclase. Hypotensive and vasodilatory agent. Induces neuronal differentiation in stem cells and in several neuroblastoma. Also available as part of the PKA Tocriset™ .Purification Methods
It is an antihypertensive, a positive ionotropic, a platelet aggregation inhibitor, and it has adenylate cyclase activating properties [Chem Abstr 89 244150 1978, de Souza et al. Med Res Rev 3 201 1983, X-ray: Tandon et al. Indian J Chem 15B 880 1977]. [Beilstein 18/5 V 55.]Forskolin 준비 용품 및 원자재
원자재
무수초산
1ALPHA,6BETA,7BETA,9ALPHA-TETRAHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
7H-1,3-Dioxolo[3,4]naphtho[2,1-b]pyran-7-one, 5-ethenyldodecahydro-8-hydroxy-2,2,3b,5,7b,11,11-heptamethyl-, (3aS,3bS,5R,7aR,7bS,8S,11aS,11bS)-
준비 용품
Forskolin 공급 업체
글로벌( 435)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 |
sales@zhswyy.com | China | 301 | 58 |
Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 |
admin@hbsaisier.cn | China | 996 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 346 | 58 |
Hebei Longbang Technology Co., LTD | +86-18032476855 +86-18032476855 |
admin@hblongbang.com | China | 935 | 58 |
HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 |
L18532138899@163.com | China | 931 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9332 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Forskolin 관련 검색:
Chaetocin
Hypericin
PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-
FORSKOLIN, 7-O-HEMISUCCINYL-7-DEACETYL,FORSKOLIN, 7-DEACETYL-7-O-HEMISUCCINYL-
Forskolin
FORSKOLIN, 1,9-DIDEOXY,FORSKOLIN, 1,9-DIDEOXY-, COLEUS FORSKOHLII
FORSKOLIN
DIHYDRO CUMINYL ALCOHOL
SUCCINYLCHOLINE CHLORIDE DIHYDRATE
FORSKOLIN, 6-ACETYL-7-DEACETYL-
FORSKOLIN, 7-DEACETYL-
N,N-DIMETHYL-(3R,4AR,5S,6AS,10S,10AR,10BS)-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-10,10B-DIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1-OXO-1H-NAPHTHO[2,1-B]PYRAN-6-YL ESTER B-ALANINE HYDROCHLORIDE
FORSKOLIN, 7-DEACETYL-7-[O-(N-METHYLPIPERAZINO)-GAMMA-BUTYRYL]-, DIHYDROCHLORIDE
7-DEACETYL-1,9-DIDEOXY-FORSKOLIN
FORSKOLIN RESIN
BODIPY(R) FL FORSKOLIN
FORSKOLIN, 7BETA-DEACETYL-7BETA-(GAMMA-N-METHYLPIPERAZINO)-BUTYRYL DIHYDROCHLORIDE
FORSKOLIN, 7BETA-DEACETYL-7BETA-[GAMMA-(MORPHOLINO) BUTYRYL]-, HYDROCHLORIDE