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Midazolam

CAS No.
59467-64-0
Chemical Name:
Midazolam
Synonyms
Midazolam;Midazolan CLH BP;7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepine-2-methanamine;1H-1,4-Benzodiazepine-2-methanamine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-;[7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine;2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1H-1,4-Benzodiazepine Dima;(7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine;[(2RS)-7-Chloro-5-(2-fluorophenyl)2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine;2-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine See A615360
CBNumber:
CB0418580
Molecular Formula:
C16H15ClFN3
Molecular Weight:
303.76
MDL Number:
MFCD00864445
MOL File:
59467-64-0.mol
Last updated:2023-05-29 13:57:48

Midazolam Properties

Boiling point 443.9±45.0 °C(Predicted)
Density 1.36
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.51±0.29(Predicted)
color Light Yellow to Dark Yellow
CAS DataBase Reference 59467-64-0(CAS DataBase Reference)
FDA UNII S9JC45ZV43

SAFETY

Risk and Safety Statements

DEA Controlled Substances CSCN: 2884
CAS SCH: IV
NARC: N

Midazolam Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An Intermediate for the synthesis of Midazolam

General Description

This drug is used intravenously as a shortactingsedative–hypnotic and as an induction anestheticbecause of its short half-life for the same reason. Further informationcan be found in the section on anesthetics.

784-38-3
106-89-8
59467-64-0
Synthesis of Midazolam from 2-Amino-5-chloro-2'-fluorobenzophenone and Epichlorohydrin

Midazolam Preparation Products And Raw materials

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepine-2-methanamine Midazolam 2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1H-1,4-Benzodiazepine Dima Midazolan CLH BP 2-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine See A615360 (7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine [7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine 1H-1,4-Benzodiazepine-2-methanamine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro- [(2RS)-7-Chloro-5-(2-fluorophenyl)2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine 59467-64-0 C16H15ClFN3 C18H13ClFN3 Chemical Amines Amines Heterocycles Intermediates