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(-)-[3R,4S]-CHROMANOL 293B

CAS No.
163163-24-4
Chemical Name:
(-)-[3R,4S]-CHROMANOL 293B
Synonyms
(-)-[3R;(-)-Chromanol 293B;4S]-Chromanol 293B;(-)-[3R,4S]-Chromano;(-)-[3R,4S]-CHROMANOL 293B;(-)-[3R,4S]-Chromanol 293B;Chromanol 293B [3R,4S]-(-)-;( ) Chromanol 293B,()Chromanol 293B;N-((3R,4S)-6-Cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-methylethanesulfonamide;N-[(3R,4S)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-METHYLETHANESULFONAMIDE
CBNumber:
CB0677882
Molecular Formula:
C15H20N2O4S
Molecular Weight:
324.4
MDL Number:
MFCD06798368
MOL File:
163163-24-4.mol
Last updated:2023-06-30 15:45:59

(-)-[3R,4S]-CHROMANOL 293B Properties

Melting point 192 °C
Boiling point 474.1±55.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO: 18 mg/mL
form solid
pka 12.96±0.60(Predicted)
color white

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36/37-7/9
WGK Germany  3

(-)-[3R,4S]-CHROMANOL 293B price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C350260 (-)-[3R,4S]-Chromanol293B 163163-24-4 1mg $45 2021-12-16 Buy
ApexBio Technology B6753 (-)-[3R,4S]-Chromanol293B 163163-24-4 10mg $297 2021-12-16 Buy
American Custom Chemicals Corporation CCH0004091 (-)-(3R,4S)-CHROMANOL 293B 95.00% 163163-24-4 5MG $505.26 2021-12-16 Buy
ApexBio Technology B6753 (-)-[3R,4S]-Chromanol293B 163163-24-4 50mg $1253 2021-12-16 Buy
Product number Packaging Price Buy
C350260 1mg $45 Buy
B6753 10mg $297 Buy
CCH0004091 5MG $505.26 Buy
B6753 50mg $1253 Buy

(-)-[3R,4S]-CHROMANOL 293B Chemical Properties,Uses,Production

Definition

ChEBI: Chromanol 293B is a 1-benzopyran.

Biological Activity

Enantiomer that selectively inhibits the slow component of delayed rectifier K + current (I Ks ). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC 50 values are 1.36 and 9.6 μ M respectively). Has negligible inhibitory action at hERG channels (IC 50 > 30 μ M).

storage

Room temperature

(-)-[3R,4S]-CHROMANOL 293B Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-[3R,4S]-CHROMANOL 293B Suppliers

Global( 24)Suppliers
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TargetMol Chemicals Inc.
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Career Henan Chemica Co
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Aladdin Scientific
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
BOC Sciences -- info@bocsci.com USA 0 65
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Shanghai Universal Biotech Co.,Ltd 13774214275 gaojun@univ-bio.com China 24990 58
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 2853979810@qq.com China 10010 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4869 58
N-[(3R,4S)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-METHYLETHANESULFONAMIDE (-)-[3R,4S]-CHROMANOL 293B Chromanol 293B [3R,4S]-(-)- Ethanesulfonamide, N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl- (-)-[3R,4S]-Chromano (-)-[3R (-)-[3R,4S]-Chromanol 293B 4S]-Chromanol 293B (-)-Chromanol 293B ( ) Chromanol 293B,()Chromanol 293B N-((3R,4S)-6-Cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-methylethanesulfonamide 163163-24-4 Potassium channel