Peiminine
- CAS No.
- 18059-10-4
- Chemical Name:
- Peiminine
- Synonyms
- Peimnine;PEINININE;PEIMININE;Peimine B;RADDEANINE;Vertieinon;Osnovanine;Zhebeinone;Fritillarine;PEIMINE (RG)
- CBNumber:
- CB0745848
- Molecular Formula:
- C27H43NO3
- Molecular Weight:
- 429.64
- MDL Number:
- MFCD00210542
- MOL File:
- 18059-10-4.mol
- MSDS File:
- SDS
| Melting point | 267° |
|---|---|
| alpha | D22 -38.5° (c = 1.5 in chloroform) |
| Boiling point | 567.1±50.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated) |
| pka | 14.56±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 18059-10-4(CAS DataBase Reference) |
| FDA UNII | QUB07U6VTQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H332-H312-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312 | |||||||||
| Safety Statements | 24/25 | |||||||||
| HS Code | 29389090 | |||||||||
| NFPA 704 |
|
Peiminine price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89533 | Peiminine phyproof? Reference Substance | 18059-10-4 | 10MG | $485 | 2024-03-01 | Buy |
| TCI Chemical | P2609 | Peiminine | 18059-10-4 | 10MG | $122 | 2024-03-01 | Buy |
| TCI Chemical | P2609 | Peiminine | 18059-10-4 | 50MG | $426 | 2024-03-01 | Buy |
| Cayman Chemical | 29618 | Peiminine | 18059-10-4 | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 29618 | Peiminine | 18059-10-4 | 50mg | $515 | 2024-03-01 | Buy |
Peiminine Chemical Properties,Uses,Production
Description
Peiminine is a natural product found in Fritillaria anhuiensis, Fritillaria ebeiensis, and other organisms with data available.It has been reported to have potent anti-inflammatory, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth.
Corydalis ochotensis var. raddeana also yields this alkaloid which must not be confused with the two bases of the same name previously isolated from Fritillaria raddeana. The structure has been determined from chemical analysis and the ultraviolet, infrared, NMR and mass spectra.
Chemical Properties
Peiminine is an alkaloid isolated from the Chinese drug 'Pei-Mu', the 'Szechuan' variety of which is stated to be obtained from the corms of Fritillaria RoyZei Hook. This base was first prepared by Chou and Chen who gave it the formula C18H22O2N. Other formulae assigned to the alkaloid are C26H43O2N and C25H41O3N. Peiminine yields colourless needles from EtOH and is laevorotatory having [a]D18 - 67.3° (EtOH). It forms a hydrochloride, m.p. 295-8°C; hydrobromide, m.p. 292°C; oxime, m.p. 10SoC (dec.); semicarbazone, m.p. 255-6°C and the phenylhydrazone hydrochloride, m.p. 266°C. The acetyl derivative yields colourless needles from Me2CO, m.p. 174°C, giving a hydrochloride, m.p. 268°C. Chi and his co-workers have found that the free base sinters at 140°C, melts at 147- 8°C and again at 225-6°C after intermediate solidification. These authors consider the alkaloid to be identical with verticilline (q.v.).
Uses
Peiminine is a derivative of Peimine (P218375) a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants.
Definition
ChEBI: Imperialine is an alkaloid.
References
Kametani et al., Heterocycles, 4, 723 (1976)
Peiminine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from Peiminine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Peiminine
18059-10-4
|
US $71.00-186.00 / mg | ≥95% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-04-12 | Peiminine
18059-10-4
|
US $0.00-0.00 / KG | 1KG | 99% | 50000kg/year | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2023-02-24 | Peiminine
18059-10-4
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |