ChemicalBook >> CAS DataBase List >>Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)-

Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)-

Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- structure

CAS No.: 393794-17-7

Chemical Name:: Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)-

Synonyms: MLR24;MLR-24;MLR 24;Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)-

CBNumber:: CB08739166

Molecular Formula:: C28H24F3NO6

Molecular Weight:: 527.49

MDL Number:

MOL File:: 393794-17-7.mol

Last updated:2023-04-23 13:52:06

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Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Properties

Boiling point	585.5±50.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	RT
solubility	Soluble in DMSO (up to 30 mg/ml)
form	solid
pka	3.22±0.10(Predicted)
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Chemical Properties,Uses,Production

Description

MRL-24 (393794-17-7) displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. MRL-24 is highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.

References

1) Choi?et al.?(2010),?Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by CDK5;? Nature,?466?451

Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Preparation Products And Raw materials

Raw materials

Preparation Products

Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
TargetMol Chemicals Inc.	58

393794-17-7(Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)-)Related Search:

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Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- MLR 24 MLR24 MLR-24 393794-17-7