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Copper Peptide

Copper Peptide Structure
Copper Peptide structure
CAS No.
49557-75-7
Chemical Name:
Copper Peptide
Synonyms
GHK;Ahk-cu;Glycyl-L-Histidyl-L-Lysine;GHK Cu Copper Peptide;Tripeptide-1 Copper;Copper Peptide AHK-Cu;Cu-GHK;Copper peptides;Copper Peptide powder (GHK-cu);GHK2-CU
CBNumber:
CB0875341
Molecular Formula:
C14H24N6O4
Molecular Weight:
340.38
MDL Number:
MFCD00036754
MOL File:
49557-75-7.mol
Last updated:2024-11-20 11:41:24
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Copper Peptide Properties

Melting point >144°C (dec.)
Boiling point 831.0±65.0 °C(Predicted)
Density 1.324
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Aqueous Acid (Slightly), DMSO (Slightly)
form Solid
pka 3.11±0.10(Predicted)
color Off-White
Sequence Copper gly-his-lys
Stability Hygroscopic
InChIKey MVORZMQFXBLMHM-QWRGUYRKSA-N
SMILES C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CN
EWG's Food Scores 1
FDA UNII 39TG2H631E

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338

Copper Peptide price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27168 GHK 49557-75-7 5mg $109 2024-03-01 Buy
Cayman Chemical 27168 GHK 49557-75-7 10mg $153 2024-03-01 Buy
Cayman Chemical 27168 GHK 49557-75-7 1mg $32 2024-03-01 Buy
TRC G625230 Glycyl-L-histidyl-L-lysine 49557-75-7 250mg $165 2021-12-16 Buy
American Custom Chemicals Corporation COS0000052 COPPER TRIPEPTIDE 95.00% 49557-75-7 1G $216.3 2021-12-16 Buy
Product number Packaging Price Buy
27168 5mg $109 Buy
27168 10mg $153 Buy
27168 1mg $32 Buy
G625230 250mg $165 Buy
COS0000052 1G $216.3 Buy

Copper Peptide Chemical Properties,Uses,Production

Description

Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.

Uses

Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.

Uses

anti-wrikle

Uses

Copper Peptide(GHK-Cu) can be used as skin antiaging agents.

Definition

ChEBI: A tripeptide composed of glycine, L-histidine and L-lysine residues joined in sequence.

Biological Functions

When applied topically, copper peptide works as an antioxidant, promote collagen and elastin production, and soften the appearance of fine lines and wrinkles.

Pharmaceutical Applications

Glycyl-l-histidyl-l-lysine (GHK) is a tripeptide known for its high binding affinity to Cu2+ and its complex role in wound healing. The GHK–Cu(II) complex was isolated from human plasma in the 1970s and it was shown to be an activator for wound healing. GHK–Cu(II) has two main functions: as an anti-inflammatory agent to protect the tissue from oxidative damage after the injury, and as an activator for wound healing itself as it activates the tissue remodelling.
The structure of GHK is very similar to that of common drugs used to treat ulcers.
After the initial stages of wound healing are activated, such as blood coagulation and neutrophil invasion, a second stage of wound healing begins, which includes the population of GHK at the wound, which has a high affinity to Cu2+. Mast cells, which are located in the skin, secrete GHK, which accumulates Cu2+ and forms the copper complex GHK–Cu(II) and therefore increases the metal–tripeptide concentration at the wound. First, GHK–Cu(II) has an anti-inflammatory effect by protecting the tissue from oxidative damage and by suppressing local inflammatory signals (i.e. cytokine interleukin-1 (IL-1)). Second, GHK–Cu(II) is released into the blood stream and encourages the production of wound macrophages that support the wound repair by removing the damaged tissue and secreting a family of several growth factor proteins. GHK–Cu(II) also hinders fibroblast production of TGF-β-1 and therefore suppresses the scar development. The GHK–Cu(II) complex also stimulates the growth of blood vessels, neurons and elastin, and, in general, supports most processes of wound healing.

Side effects

While Copper Peptide Serum is generally safe to use, you should be aware of potential side effects that may occur. Although rare, some individuals may experience skin irritation or redness after applying the serum. This can be due to sensitivity to the ingredients or an allergic reaction. Another potential side effect of Copper Peptide Serum is increased sensitivity to sunlight. The serum can make your skin more prone to sunburn.

Copper Peptide synthesis

29022-11-5
71989-26-9
109425-51-6
49557-75-7
Synthesis of Copper Peptide from Fmoc-Gly-OH and Fmoc-Lys(Boc)-OH and Fmoc-His(Trt)-OH

Copper Peptide Preparation Products And Raw materials

Raw materials

Fmoc-His(Trt)-OH Fmoc-Lys(Boc)-OH Fmoc-Gly-OH

Preparation Products

Copper Peptide Suppliers

Global( 453)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Likang New Materials Co., Limited 		+86-16631818819 +86-17736933208 3684455296@qq.com China 9300 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2993 58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
+86-519-85525359 +86-15995072465 sales@xuanmingchem.com China 914 58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
+86-029-86333380 18829239519 sales06@tgybio.com China 902 58
ZhenYiBio Technology Inc
+8615309206328 alexxue@zhenyibio.com China 296 58
Zhuzhou New Peptides Tech Co.,Ltd.
+86-18073326374 +86-18073326374 sales@goodpeptides.com China 56 58
Wuhan Haorong Biotechnology Co.,ltd
+86-18565342920; +8618565342920 sales@chembj.net China 289 58
Sigma Audley
+86-15937194204 +86-18126314766 nova@sh-teruiop.com China 467 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+8618580541567 sales@zhswyy.com China 303 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8812 58
Supplier Advantage
Shanghai Likang New Materials Co., Limited 		58
Xi'an Kono chem co., Ltd.,
58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
58
ZhenYiBio Technology Inc
58
Zhuzhou New Peptides Tech Co.,Ltd.
58
Wuhan Haorong Biotechnology Co.,ltd
58
Sigma Audley
58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
58
Hebei Weibang Biotechnology Co., Ltd 		58

Related articles

  • Benefits of Copper Peptide
  • Copper peptide (GHK-Cu), also known as liver cell growth factor, is the naturally occurring tripeptide glycyl-L-histidyl-L-lys....
  • Feb 16，2022

View Lastest Price from Copper Peptide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Copper Peptide / GHK-Cu pictures 2024-11-21 Copper Peptide / GHK-Cu
49557-75-7
 US $0.00-0.00 / g/Bag 10g/Bag 98% up 20 tons Sinoway Industrial co., ltd.
GHK-CU Copper Peptide(GHK-Cu) pictures 2024-11-21 GHK-CU Copper Peptide(GHK-Cu)
49557-75-7
 US $0.00 / G 1G 99% 20 CONTIDE BIOTECH CO.,LTD
Copper Peptide pictures 2024-11-21 Copper Peptide
49557-75-7
 US $1.00 / g 1g 99% 100kg Dorne Chemical Technology co. LTD
  • Copper Peptide pictures
  • Copper Peptide
    49557-75-7
  • US $1.00 / g
  • 99%
  • Dorne Chemical Technology co. LTD

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L-Lysine,glycyl-L-histidyl- Liver Cell Growth Factor(GHK) GHKcu/Growth-Modulating peptide (Gly-His-Lys)2Cu.xHAc AHK-Cu (Copper Peptide) Lipopeptide Acetate / Palmitoyl Hexapeptide (GHK)2Cu, GHK-Cu, GHK Copper glycyl-histidyl-lysine H-Gly-His-Lys-OH：Cu (2S)-6-Amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid Growth-modulating peptide Liver growth factor Gly-His-Lys-Cu COPPER PEPTIDE(GHK-CU) Ghk-Cu Peptides Copper Tripeptide-1(GHK-Cu, GHK-Copper) Copper Tripeptide-1 (GHK-Cu) GCU21P Glycyl-l-histidyl-l-lysine USP/EP/BP CHK.Cu copper peptide (ghk-cu / copper peptide) ALANINE/HISTIDINE/LYSINEPOLYPEPTIDECOPPERHCL(1:1) Copper Peptide AHK-Cu (S)-6-Amino-2-((S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido)hexanoic acid Cu-GHK GHK Cu Copper Peptide Copper Peptide powder (GHK-cu) GHK Cu Copper Peptide GHK.Cu GHK-Cu Ahk-cu Glycyl-L-Histidyl-L-Lysine GHK Cooper Peptide Tripeptide-1 Copper GHK2-CU Copper peptide (GHK) Glycyl--histidyl-l-lysine Copper Peptide(GHK-Cu, GHK-Copper) Blue-cupric peptide Copper peptides Sansheng peptide Growth-modulating peptide/Liver growth factor TRIOEOTIDE-1 Blue copper peptide Copper Peptide / Glycyl-L-Histidyl-L-Lysine GHK-CU Copper Peptide(GHK-Cu) CB0875341 Glycyl-L-Histasyl-L-Lysine OPPER TRIPEPTIDE-1 49557-75-7 丙氨酸-L-组氨酰-L-赖氨酸 9030-95-5 BEAUTY PEPTIDES cosmestic APIs 49557-75-7