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methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride

CAS No.
7210-92-6
Chemical Name:
methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride
Synonyms
Baycaine;Tolycaine hydrochloride;LIWOWASNSWUKPF-UHFFFAOYSA-N;methyl 2-[[2-(diethylamino)acetyl]amino]-3-methylbenzoate,hydrochloride;methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride;Benzoic acid,2-[[2-(diethylamino)acetyl]amino]-3-methyl-, methyl ester, hydrochloride (1:1)
CBNumber:
CB0888921
Molecular Formula:
C15H23ClN2O3
Molecular Weight:
314.80772
MDL Number:
MOL File:
7210-92-6.mol
Last updated:2023-05-04 17:34:41

methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Properties

Melting point 139-140.5°
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
FDA UNII 23212OEY8I

methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T536625 TolycaineHydrochloride 7210-92-6 100mg $185 2021-12-16 Buy
Usbiological 467720 Tolycaine Hydrochloride 7210-92-6 100mg $460 2021-12-16 Buy
TRC T536625 TolycaineHydrochloride 7210-92-6 1g $1455 2021-12-16 Buy
American Custom Chemicals Corporation API0004449 TOLYCAINE HYDROCHLORIDE 95.00% 7210-92-6 5MG $505.3 2021-12-16 Buy
Medical Isotopes, Inc. 48990 TolycaineHCl 7210-92-6 100mg $650 2021-12-16 Buy
Product number Packaging Price Buy
T536625 100mg $185 Buy
467720 100mg $460 Buy
T536625 1g $1455 Buy
API0004449 5MG $505.3 Buy
48990 100mg $650 Buy

methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Chemical Properties,Uses,Production

Originator

Tolycaine Hydrochloride,ZYF Pharm Chemical

Uses

Tolycaine Hydrochloride is an anesthetic drug.

Definition

ChEBI: Tolycaine hydrochloride is an amidobenzoic acid.

Manufacturing Process

A suspension of 40 g 2-amino-3-methylbenzoic acid methyl ester in 125 ml of benzene was added 125 ml of saturated solution of sodium acetate and then at 0-5°C was added 37 g chloracetylchloride. The mixture was stirred for 1 hour at room temperature. The mixture was filtered. The organic layer was with 10% solution of potassium carbonate and dries under calcium chloride. By distillation of the mixture was obtained 15 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl ester; melting point 86-87.5°C (crystallization from a mixture acetic acid and ligroin); yield 21.8 g.
A mixture of 16 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl ester and 10 g diethyl amine in benzene was refluxed for 5 hours. After cooling the diethyl amine hydrochloride was deleted by filtration. The organic layer was washed with 2 N hydrochloric acid. To the solution was added potassium carbonate. The product was extracted with ether and distilled.

Therapeutic Function

Local anesthetic

methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Preparation Products And Raw materials

methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Hu Bei Jiutian Bio-medical Technology CO.,Ltd
027-88013699 17354350817 Ryan@jiutian-bio.com China 7431 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4966 55
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 1052@dideu.com China 10011 58
methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Baycaine Tolycaine hydrochloride LIWOWASNSWUKPF-UHFFFAOYSA-N methyl 2-[[2-(diethylamino)acetyl]amino]-3-methylbenzoate,hydrochloride Benzoic acid,2-[[2-(diethylamino)acetyl]amino]-3-methyl-, methyl ester, hydrochloride (1:1) 7210-92-6