ChemicalBook >> CAS DataBase List >>2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E
2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E
- CAS No.
- 141286-78-4
- Chemical Name:
- 2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E
- Synonyms
- PEPA,inhibit,Inhibitor,iGluR,Ionotropic glutamate receptors;2-[2,6-Difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]acetamide;Acetamide, 2-[2,6-difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]-;2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide (PEPA)
- CBNumber:
- CB0972925
- Molecular Formula:
- C16H16F2N2O4S2
- Molecular Weight:
- 402.44
- MDL Number:
- MFCD04974493
- MOL File:
- 141286-78-4.mol
- MSDS File:
- SDS
Last updated:2024-11-19 20:33:22
| Boiling point | 617.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | protect from light |
| solubility | DMSO: >20mg/mL |
| form | solid |
| pka | 10.44±0.40(Predicted) |
| color | white |
| InChIKey | GTACSIONMHMRPD-UHFFFAOYSA-N |
| FDA UNII | 8S4PR7A8JS |
2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D8941 | 2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide ≥98% (HPLC), solid | 141286-78-4 | 5mg | $178 | 2024-03-01 | Buy |
| Sigma-Aldrich | D8941 | 2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide ≥98% (HPLC), solid | 141286-78-4 | 25mg | $728 | 2024-03-01 | Buy |
| Cayman Chemical | 29190 | PEPA | 141286-78-4 | 5mg | $88 | 2024-03-01 | Buy |
| Cayman Chemical | 29190 | PEPA | 141286-78-4 | 10mg | $121 | 2024-03-01 | Buy |
| TRC | P999023 | PEPA | 141286-78-4 | 25mg | $190 | 2021-12-16 | Buy |
2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E Chemical Properties,Uses,Production
Uses
PEPA is an allosteric potentiator of AMPA desensitization.
Biological Activity
Novel allosteric potentiator of AMPA receptor desensitization. Slows the rate of onset of desensitization and potentiates steady-state equilibrium currents induced by glutamate with subunit (GluR3/4 > GluR1) and splice variant (flop > flip) selectivity. Ameliorates post-ischemic memory impairment in rats following i.v. administration.
Biochem/physiol Actions
2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats.
2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 54)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30240 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1249 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5984 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
View Lastest Price from 2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E manufacturers
141286-78-4(2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E)Related Search:
2-[2,6-Difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]acetamide
2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide (PEPA)
PEPA,inhibit,Inhibitor,iGluR,Ionotropic glutamate receptors
Acetamide, 2-[2,6-difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]-
141286-78-4
C16H16N2O4S2F2