ChemicalBook >> CAS DataBase List >>Bupranolol
Bupranolol
- CAS No.
- 14556-46-8
- Chemical Name:
- Bupranolol
- Synonyms
- Bupranol;Bupranolol;Ophtorenin;BRN 2272923;Bupranololum;KL 255Ophtorenin;Bupranolol, 10 mM in DMSO;Bupranolol, beta adrenoceptor antagonist;B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN;1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol
- CBNumber:
- CB11118303
- Molecular Formula:
- C14H22ClNO2
- Molecular Weight:
- 271.78
- MDL Number:
- MOL File:
- 14556-46-8.mol
Last updated:2024-11-19 23:02:33
Melting point | 71-74°C |
---|---|
Boiling point | 396.3±42.0 °C(Predicted) |
Density | 1.098±0.06 g/cm3(Predicted) |
storage temp. | Hygroscopic, Refrigerator, Under Inert Atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 13.82±0.20(Predicted) |
color | White to Off-White |
FDA UNII | 858YGI5PIT |
ATC code | C07AA19 |
Bupranolol price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B689650 | Bupranolol | 14556-46-8 | 500mg | $215 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000484 | BUPRANOLOL 95.00% | 14556-46-8 | 5MG | $496.82 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 44129 | Bupranolol | 14556-46-8 | 5G | $2400 | 2021-12-16 | Buy |
Bupranolol Chemical Properties,Uses,Production
Originator
Betadrenol,Pharma-Schwarz,W. Germany,1969
Uses
Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.
Definition
ChEBI: Bupranolol is an aromatic ether.
Manufacturing Process
A mixture of 16.3 g of (2-chloro-5-methylphenyl)glycidic ether (from epichlorohydrin and 2-chloro-5-methylphenol) and 6.2 g of t-butylamine in 50 ml of ethanol is heated at reflux for 6 hours. The solvent is removed, the residue is washed with water and then extracted with benzene. The dried extract is evaporated to give 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2- propanol. Treatment of the free base in benzene solution with dry hydrogen chloride yields the hydrochloride salt.
Therapeutic Function
Antiarrhythmic
Bupranolol Preparation Products And Raw materials
Global( 39)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
Chengdu Kamel Pharmaceutical Co., Ltd | 028-67136579 15828051124 | sales@kamelpharm.com | China | 2001 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9805 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 5960 | 55 |
View Lastest Price from Bupranolol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-11-19 | Bupranolol
14556-46-8
|
US $46.00-170.00 / mg | 95.85% | 10g | TargetMol Chemicals Inc. |
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- Bupranolol
14556-46-8
- US $46.00-170.00 / mg
- 95.85%
- TargetMol Chemicals Inc.
(2S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
(S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol
1-[(2-Chloro-5-methylphenyl)oxy]-3-[(1,1-dimethylethyl)amino]propan-2-ol
Bupranolol
2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-
2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]- (8CI)
Bupranol
Ophtorenin
B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN
BRN 2272923
Bupranololum
KL 255Ophtorenin
non-selective,competitive,Adrenergic Receptor,Bupranolol,Inhibitor,intrinsic,sympathomimetic,active,Beta Receptor,inhibit,orally
Bupranolol, beta adrenoceptor antagonist
Bupranolol, 10 mM in DMSO
14556-46-8