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ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE structure

CAS No.: 124755-24-4

Chemical Name:: ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE

Synonyms: ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE;Ethyl 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]acetate;Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate;Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 97%;Di(3,3,3-trifluoroethyl)(ethoxycarbonylmethyl)phosphonate;[Bis-(2,2,2-trifluoro-ethoxy)-phosphoryl]-acetic acid ethyl ester;[BIS-(2,2,2-TRIFLUORO-ETHOXY)-PHOSPHORYL]-ACETIC ACID METHYL ESTER;Acetic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester

CBNumber:: CB1206274

Molecular Formula:: C8H11F6O5P

Molecular Weight:: 332.13

MDL Number:: MFCD01318337

MOL File:: 124755-24-4.mol

Last updated:2022-12-12 11:56:02

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ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Properties

Boiling point	249-250 °C(lit.)
Density	1.403 g/mL at 25 °C(lit.)
refractive index	n20/D 1.3730(lit.)
Flash point	>230 °F
InChIKey	HBYHPBCAZBLFTD-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	E677510	Ethyl[Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate	124755-24-4	1g	$100	2021-12-16	Buy
Ark Pharm	P000231421	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	124755-24-4	5g	$102	2021-12-16	Buy
AK Scientific	Z4021	Ethyl2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate	124755-24-4	5g	$237	2021-12-16	Buy
Ark Pharm	P000231421	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	124755-24-4	25g	$403	2021-12-16	Buy
Ark Pharm	P000231421	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	124755-24-4	10g	$170	2021-12-16	Buy

Product number	Packaging	Price	Buy
E677510	1g	$100	Buy
P000231421	5g	$102	Buy
Z4021	5g	$237	Buy
P000231421	25g	$403	Buy
P000231421	10g	$170	Buy

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Chemical Properties,Uses,Production

Uses

Ethyl [Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate is a reagent used in the preparation of spiroketal EBC-23; an anticancer agent, scytonemin A; a novel calcium antagonist and other useful organic compounds.

Synthesis

To stirred solution of 18-crown-6 (4.40 g, 16.65 mmol), THF (20 mL), and bis (2,2,2-trifluoroethyl) phosphite (1) (0.55 mL, 3.75 mmol), KHMDS (8.0 mL, 4.00 mmol, 0.5 M in toluene) was added via syringe in a dropwise manner at -78 oC. Ethyl chloroacetate (0.35 mL, 3.30 mmol) was added to the flask after 15 min. The reaction flask was allowed to warm to room temperature and stir for 4 hr. After standard workup procedure, the crude product was then purified by flash column chromatography (2:1-1:1 hexanes:EtOAc, Rf = 0.25 in 2:1 hexanes:EtOAc) yielding Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate (808 mg, 2.43 mmol, 73.4%) as a yellow syrup.

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE synthesis

Synthesis of ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE from BIS(2 2 2-TRIFLUOROETHYL)METHYLPHOSPHON&

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Preparation Products And Raw materials

Raw materials

Acetic acid, (dichlorophosphinyl)-, ethyl ester BIS(2 2 2-TRIFLUOROETHYL)METHYLPHOSPHON& BIS(2,2,2-TRIFLUOROETHYL) PHOSPHITE Ethyl chloroformate Ethyl bromoacetate

2,2,2-Trifluoroethanol

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Preparation Products

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Suppliers

Global( 63)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29798	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Shaanxi Dideu Medichem Co. Ltd	18192627656	1012@dideu.com	China	1636	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4022	58
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	13141	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33350	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hubei xin bonus chemical co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	58
Henan Alfa Chemical Co., Ltd	58
LEAP CHEM CO., LTD.	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-03-16	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 124755-24-4	US $1.00-0.00 / KG	1KG	99%	50 tons	Shaanxi Dideu Medichem Co. Ltd

Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate
124755-24-4
US $1.00-0.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

124755-24-4(ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE)Related Search:

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BIS(2,2,2-TRIFLUOROETHYL) (METHOXYCARBONYLMETHYL)PHOSPHONATE

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Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate [BIS-(2,2,2-TRIFLUORO-ETHOXY)-PHOSPHORYL]-ACETIC ACID METHYL ESTER ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 97% Acetic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester [Bis-(2,2,2-trifluoro-ethoxy)-phosphoryl]-acetic acid ethyl ester Di(3,3,3-trifluoroethyl)(ethoxycarbonylmethyl)phosphonate Ethyl 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 124755-24-4 C8H11F6O5P Organic Building Blocks Building Blocks Phosphonates/Phosphinates Phosphorus Compounds Organic Building Blocks Phosphonates/Phosphinates Phosphorus Compounds