ChemicalBook >> CAS DataBase List >>Triclabendazole
Triclabendazole
- CAS No.
- 68786-66-3
- Chemical Name:
- Triclabendazole
- Synonyms
- Triclabendazol;Tricalbendazole;6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE;FASINEX;CGA-89317;snalvbendaz;TRICLABENDAZOLE;CGA-89317, Egaten;Triclabendazole EP;Triclabendazole CRS
- CBNumber:
- CB1282896
- Molecular Formula:
- C14H9Cl3N2OS
- Molecular Weight:
- 359.66
- MDL Number:
- MFCD00864519
- MOL File:
- 68786-66-3.mol
- MSDS File:
- SDS
Last updated:2024-11-06 15:28:16
| Melting point | 175-176°C |
|---|---|
| Boiling point | 240.6°C (rough estimate) |
| Density | 1.3875 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| pka | 7.91±0.10(Predicted) |
| color | White to Beige |
| Merck | 14,9652 |
| BCS Class | 4/3 |
| Stability | Stability |
| InChI | InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19) |
| InChIKey | NQPDXQQQCQDHHW-UHFFFAOYSA-N |
| SMILES | C1(SC)NC2=CC(Cl)=C(OC3=CC=CC(Cl)=C3Cl)C=C2N=1 |
| CAS DataBase Reference | 68786-66-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4784C8E03O |
| ATC code | P02BX04 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DD6747000 | |||||||||
| HS Code | 29339900 | |||||||||
| Toxicity | LD50 oral in rabbit: 206mg/kg | |||||||||
| NFPA 704 |
|
Triclabendazole price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001737 | Triclabendazole EuropePharmacopoeia (EP) Reference Standard | 68786-66-3 | y0001737 | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0001723 | Triclabendazole for system suitability EuropePharmacopoeia (EP) Reference Standard | 68786-66-3 | y0001723 | $153 | 2024-03-01 | Buy |
| TCI Chemical | T2826 | Triclabendazole >98.0%(HPLC)(T) | 68786-66-3 | 1g | $29 | 2024-03-01 | Buy |
| TCI Chemical | T2826 | Triclabendazole >98.0%(HPLC)(T) | 68786-66-3 | 5g | $79 | 2024-03-01 | Buy |
| Cayman Chemical | 18883 | Triclabendazole ≥98% | 68786-66-3 | 1g | $72 | 2024-03-01 | Buy |
Triclabendazole Chemical Properties,Uses,Production
Description
Triclabendazole is a benzimidazole anthelmintic. It eliminates both immature and adult flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg. Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.
Chemical Properties
Off-White Solid
Uses
An anthelmintic (fasciola).
Uses
Triclabendazole is classified under the category of ‘Anthelmintic flukicide for veterinary use.
Definition
ChEBI: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole is an aromatic ether.
Synthesis of Triclabendazole from 5-chloro-6-(2,3-dichorophenoxy)-2-thio-1H-benzimidazole and Iodomethane
Triclabendazole Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 399)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8816 | 58 |
| Hubei Langyou International Trading Co., Ltd | +86-18874586545 +86-18874586545 | linda@xrdchem.cn | China | 196 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5986 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | admin@hbsaisier.cn | China | 1015 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 852 | 58 |
Related articles
- A brief introduction to triclabendazole
- Triclabendazole, also known as CGA 89317 or CGP 23030, is an orally bioavailable anthelmintic against infections caused by Fas....
- Jan 5，2024
View Lastest Price from Triclabendazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-07 | 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
68786-66-3
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | |
 |
2024-11-07 | 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
68786-66-3
|
US $6.00 / kg | 1kg | More than 99% | 2000KG/Month | Hebei Longbang Technology Co., Ltd | |
 |
2024-11-07 | Triclabendazole
68786-66-3
|
US $8.00 / kg | 1kg | 99% | 200000 | Hebei Jingbo New Material Technology Co., Ltd |
-
- 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
68786-66-3
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
-
- 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
68786-66-3
- US $6.00 / kg
- More than 99%
- Hebei Longbang Technology Co., Ltd
-
- Triclabendazole
68786-66-3
- US $8.00 / kg
- 99%
- Hebei Jingbo New Material Technology Co., Ltd
68786-66-3(Triclabendazole)Related Search:
FASINEX
CGA-89317
5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE
TRICLABENDAZOLE
5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol
5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex
1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-
5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-1H-BENZIMIDAZOL(TRICLABENDAZOLE)
6-Chloro-5-(2,3-dichlorophenoxy)-2-(Methylthio)-1H-benzo[d]iMidazole
5-Chloro-6-(2,3-dichlorophenoxy)-2-MethylthiobenziMidazole
CGA-89317, Egaten
5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole
6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole
1H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-
5-Chloro-6 (2,3-Dichlorophenoxy)-2- Methylthio-1H- Bezimidazole
Triclabendazole for system suitability
6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole
snalvbendaz
Triclabendazole Standard
Triclabendazole CRS
Triclabendazole for system suitability CRS
6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole
Triclabendazole USP/EP/BP
Triclabendazole (CGA89317)
Triclabendazole (Y0001737)
6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE
Tricalbendazole
Triclabendazol
Triclabendazole EP
Triclabendazole API
Trichlorobenzimidazole
Triclabendazole (25 mg)
Triclabendazole in Methanol
C17795000 Triclabendazole
Triclabendazole 100 μg/ml Acetonitrile
68786-66-3
68788-66-3
68766-86-3
168786-66-3
C14H19Cl3N2OS
C14H9Cl3N2OS
Veterinary drugs
APIs
Intermediates & Fine Chemicals
Pharmaceuticals
API's
Pharmaceutical intermediate
68786-66-3