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Maleimide-NH-PEG6-CH2CH2COOPFP Ester

CAS No.
1599432-34-4
Chemical Name:
Maleimide-NH-PEG6-CH2CH2COOPFP Ester
Synonyms
Mal-amido-PEG6-PFP Ester;Mal-NH-PEG6-CH2CH2COOPFP ester;Maleimide-NH-PEG6-CH2CH2COOPFP Ester;4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber:
CB13309451
Molecular Formula:
C28H35F5N2O11
Molecular Weight:
670.58
MDL Number:
MFCD34470032
MOL File:
1599432-34-4.mol
Last updated:2023-02-23 14:24:01

Maleimide-NH-PEG6-CH2CH2COOPFP Ester Properties

Boiling point 736.0±60.0 °C(Predicted)
Density 1.345±0.06 g/cm3(Predicted)
pka 15.01±0.46(Predicted)

Maleimide-NH-PEG6-CH2CH2COOPFP Ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
purepeg 436306 Maleimide-NH-PEG6-CH2CH2COOPFPEster min.97% 1599432-34-4 1g $600 2021-12-16 Buy
Product number Packaging Price Buy
436306 1g $600 Buy

Maleimide-NH-PEG6-CH2CH2COOPFP Ester Chemical Properties,Uses,Production

Biological Activity

Mal-NH-PEG6-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Maleimide-NH-PEG6-CH2CH2COOPFP Ester Preparation Products And Raw materials

Raw materials

Preparation Products

Maleimide-NH-PEG6-CH2CH2COOPFP Ester Suppliers

Global( 13)Suppliers
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9i LLC
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TargetMol Chemicals Inc.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Chemleader Biomedical Co., Limited. 021-58180488 sales@Medchemleader.com China 1005 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Zhengzhou Converging Chemical Co. LTD 0371-0371-53399770 18037166334 2853031800@qq.com China 3026 58
Shandong fen Boyu Biotechnology Co.,LTD 13356310019 13356310019 boyu2024@163.com China 2638 58
Shochem (Shanghai) Co.,Ltd 13611745246 13816874662 sales@shochem.com China 540 58
Shandong Zhengtuo Pharmaceutical Technology Co., Ltd. 15666908650 meijia.sun@zheng-tuo.com China 96 58
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 hanfangpharma@126.com China 30968 58
Maleimide-NH-PEG6-CH2CH2COOPFP Ester Mal-NH-PEG6-CH2CH2COOPFP ester 4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-, 2,3,4,5,6-pentafluorophenyl ester Mal-amido-PEG6-PFP Ester 1599432-34-4