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ChemicalBook >> CAS DataBase List >>5,6ALPHA-DIHYDRO PGI2

5,6ALPHA-DIHYDRO PGI2

5,6ALPHA-DIHYDRO PGI2 Structure
5,6ALPHA-DIHYDRO PGI2 structure
CAS No.
62777-90-6
Chemical Name:
5,6ALPHA-DIHYDRO PGI2
Synonyms
6α-Prostaglandin I1;6α-Prostaglandin I1;5,6ALPHA-DIHYDRO PGI2;6ALPHA-PROSTAGLANDIN I1;RJADQDXZYFCVHV-WDONHGPHSA-N;6R,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;(6R,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6R,9α,11α,13E,15S)- (9CI)
CBNumber:
CB1409127
Molecular Formula:
C20H34O5
Molecular Weight:
354.48
MDL Number:
MFCD00797658
MOL File:
62777-90-6.mol
Last updated:2023-05-21 10:59:17
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5,6ALPHA-DIHYDRO PGI2 Properties

storage temp. Store at -20°C
solubility DMF: >10 (from (6b-PGI1); DMSO: >5 (from (6b-PGI1); Ethanol: >20 mg/ml (from (6b-PGI1); PBS pH 7.2: >80 μg (from (6b-PGI1)
form A crystalline solid

5,6ALPHA-DIHYDRO PGI2 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18110 6α-Prostaglandin I1 ≥99% 62777-90-6 1mg $64 2024-03-01 Buy
Cayman Chemical 18110 6α-Prostaglandin I1 ≥99% 62777-90-6 5mg $280 2024-03-01 Buy
Cayman Chemical 18110 6α-Prostaglandin I1 ≥99% 62777-90-6 10mg $497 2024-03-01 Buy
AK Scientific 1438AH 5,6alpha-DihydroPGI2 62777-90-6 5mg $410 2021-12-16 Buy
Product number Packaging Price Buy
18110 1mg $64 Buy
18110 5mg $280 Buy
18110 10mg $497 Buy
1438AH 5mg $410 Buy

5,6ALPHA-DIHYDRO PGI2 Chemical Properties,Uses,Production

Description

6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response.1 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).2

Definition

ChEBI: 6alpha-Prostaglandin I1 is a prostaglandins I.

References

1. Patrono, C., Rotella, C.M., Toccafondi, R.S., et al. Prostacyclin stimulates the adenylate cyclase system of human thyroid tissue Prostaglandins 22(1),105-115(1981).
2. Whittle, B.J.R., and Moncada, S. Prostacyclin and its analogues for the therapy of thromboembolic disorders Adv. Exp. Med. Biol. 164,193-209(1984).

5,6ALPHA-DIHYDRO PGI2 Preparation Products And Raw materials

Raw materials

Preparation Products

5,6ALPHA-DIHYDRO PGI2 Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

62777-90-6(5,6ALPHA-DIHYDRO PGI2)Related Search:

5,6ALPHA-DIHYDRO PGI2
5,6ALPHA-DIHYDRO PGI2 6R,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID 6ALPHA-PROSTAGLANDIN I1 (6R,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid 6α-Prostaglandin I1 RJADQDXZYFCVHV-WDONHGPHSA-N Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6R,9α,11α,13E,15S)- (9CI) 6α-Prostaglandin I1 62777-90-6