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PF-6274484

PF-6274484 Structure
PF-6274484 structure
CAS No.
1035638-91-5
Chemical Name:
PF-6274484
Synonyms
PF-6274484;PF-6274484 >=98% (HPLC);N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-;oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor
CBNumber:
CB14666748
Molecular Formula:
C18H14ClFN4O2
Molecular Weight:
372.78
MDL Number:
MFCD30182370
MOL File:
1035638-91-5.mol
Last updated:2024-11-19 15:53:33
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PF-6274484 Properties

storage temp. Store at -20°C
solubility DMF: 33 mg/ml; DMSO: 25 mg/ml
form A crystalline solid
color Light yellow to orange

PF-6274484 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22698 PF-6274484 ≥98% 1035638-91-5 1mg $34 2024-03-01 Buy
Cayman Chemical 22698 PF-6274484 ≥98% 1035638-91-5 5mg $100 2024-03-01 Buy
Cayman Chemical 22698 PF-6274484 ≥98% 1035638-91-5 10mg $166 2024-03-01 Buy
TRC P294153 PF6274484 1035638-91-5 50mg $820 2021-12-16 Buy
AK Scientific 8711DW N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide 1035638-91-5 5mg $209 2021-12-16 Buy
Product number Packaging Price Buy
22698 1mg $34 Buy
22698 5mg $100 Buy
22698 10mg $166 Buy
P294153 50mg $820 Buy
8711DW 5mg $209 Buy

PF-6274484 Chemical Properties,Uses,Production

Description

PF-6274484 is an irreversible EGFR kinase inhibitor that covalently reacts with active-site cysteine residues in the ATP binding pocket. PF-6274484 inhibits autophosphorylation of both wild type and mutant EGFR in tumor cells with IC50 values of 5.8 nM and 6.6 nM, respectively.

PF-6274484 Preparation Products And Raw materials

Raw materials

Preparation Products

PF-6274484 Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 4966 55
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29785 68
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44806 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58

View Lastest Price from PF-6274484 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PF-6274484 pictures 2024-11-19 PF-6274484
1035638-91-5
 US $34.00-93.00 / mg 97.71% 10g TargetMol Chemicals Inc.
  • PF-6274484 pictures
  • PF-6274484
    1035638-91-5
  • US $34.00-93.00 / mg
  • 97.71%
  • TargetMol Chemicals Inc.

PF-6274484 Spectrum

PF-6274484(1035638-91-5)1HNMR

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PF-6274484 N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]- PF-6274484 >=98% (HPLC) oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide 1035638-91-5