ChemicalBook >> CAS DataBase List >>Sodium thiomethoxide
Sodium thiomethoxide
- CAS No.
- 5188-07-8
- Chemical Name:
- Sodium thiomethoxide
- Synonyms
- SODIUM METHANETHIOLATE;SODIUM METHYL MERCAPTIDE;METHYL MERCAPTAN SODIUM SALT;Sodium thiomethylate;Sodium methylthiolate;SODIUM METHYLMERCAPTAN;SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM);Sodium me;thioformate;methanethiolate
- CBNumber:
- CB1476576
- Molecular Formula:
- CH3NaS
- Molecular Weight:
- 70.09
- MDL Number:
- MFCD00174316
- MOL File:
- 5188-07-8.mol
Last updated:2024-11-06 18:33:45
| Density | 1.12[at 20℃] |
|---|---|
| vapor pressure | 29hPa at 25℃ |
| Flash point | 27°C |
| storage temp. | Air and moisture sensitive. Store under inert gas. Sensitive to carbon dioxide Exposure to moisture. |
| solubility | soluble in Water |
| form | Powder |
| color | White to off-white |
| Water Solubility | soluble |
| Merck | 14,5956 |
| BRN | 3592983 |
| InChI | InChI=1S/CH4S.Na/c1-2;/h2H,1H3;/q;+1/p-1 |
| InChIKey | RMBAVIFYHOYIFM-UHFFFAOYSA-M |
| SMILES | CS[Na] |
| LogP | -2.33 at 20℃ |
| CAS DataBase Reference | 5188-07-8(CAS DataBase Reference) |
| FDA UNII | LB29JWW8H7 |
| EPA Substance Registry System | Methanethiol, sodium salt (5188-07-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302-H314 | |||||||||
| Precautionary statements | P210-P280-P301+P312+P330-P301+P330+P331-P303+P361+P353-P305+P351+P338+P310 | |||||||||
| Hazard Codes | C,F | |||||||||
| Risk Statements | 31-34-20/21/22-11-35-25-10 | |||||||||
| Safety Statements | 26-36/37/39-45-16 | |||||||||
| RIDADR | UN 3263 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 1-34-10-13 | |||||||||
| HazardClass | 4.3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
Sodium thiomethoxide price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 281018 | Sodium thiomethoxide 95% | 5188-07-8 | 1g | $46.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 281018 | Sodium thiomethoxide 95% | 5188-07-8 | 5g | $125 | 2024-03-01 | Buy |
| TCI Chemical | M0096 | Methyl Mercaptan Sodium Salt (ca. 15% in Water) | 5188-07-8 | 25g | $38 | 2024-03-01 | Buy |
| TCI Chemical | M0096 | Methyl Mercaptan Sodium Salt (ca. 15% in Water) | 5188-07-8 | 500g | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | 71742 | Sodium methanethiolate technical, ≥90% (RT) | 5188-07-8 | 5g | $122 | 2024-03-01 | Buy |
Sodium thiomethoxide Chemical Properties,Uses,Production
Description
Sodium methanethiolate or sodium thiomethoxide (CH3SNa, MeSNa) is the sodium conjugate base of methanethiol. This compound is commercially available as a white solid. Sodium Methanethiolate is used as a nucleophile in organic synthesis. This compound is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors. It reacts with trifluoroacetic acid and water to produce the active form of sodium trifluoroacetate. The reaction mechanism is likely due to the formation of a bicyclic heterocycle that has been shown to be effective against a number of bacteria.
Chemical Properties
Very faint yellowish red clear liquid
Uses
Used to prepare a C-21 thioether of methyl 16-prednisolonecarboxylate by mesylate displacement.
Uses
Sodium thiomethoxide is a strong nucleophile used for the synthesis of methyl aryl sulfides from halo-arenes. Alkanethiolates are efficient reagents for SN2 dealkylation of esters and aryl ethers.
Reactivity Profile
Sodium thiomethoxide is a powerful nucleophile that can be used to prepare methylthioether and other organic compounds like ethyl bromide. Its hydrolysis in moist air produces methanethiol, which has a low odor threshold and a noxious fecal smell.
Purification Methods
Dissolve the salt (10g) in EtOH (10mL) and add Et2O (100mL). Cool and collect the precipitate, wash it with Et2O and dry it in a vacuum. It is a white powder which is very soluble in EtOH and H2O. [Billmann & Jensen Bull Soc Chim Fr 3 2318 1936, Beilstein 1 III 1212.]
Sodium thiomethoxide Preparation Products And Raw materials
Raw materials
Preparation Products
2-Aminoethylmethylsulfone hydrochloride
Simetryne
Prometryn
2-(METHYLTHIO)ETHANOL
2-(Methylthio)pyrazine
4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE
2-(METHYLTHIO)THIOPHENE
Ametryn
Methylthio acetaldoxime
5-(METHYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID
ETHYL METHANESULFONYLACETATE
4-Methylthio-2-butanone
Dimethyl sulfide
METHYL MERCAPTAN
Prairie Net Wettable Powder
1of5
Global( 337)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
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Related articles
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- Jul 15，2024
Related Qustion
- Q:How to synthesis Sodium thiomethoxide
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- Aug 1，2024
View Lastest Price from Sodium thiomethoxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-06 | Sodium thiomethoxide
5188-07-8
|
US $10.00 / kg | 1kg | 99.5% | 100 | Hebei Weibang Biotechnology Co., Ltd | |
 |
2023-09-23 | Sodium thiomethoxide
5188-07-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2022-10-18 | Sodium thiomethoxide
5188-07-8
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Sodium thiomethoxide
5188-07-8
- US $10.00 / kg
- 99.5%
- Hebei Weibang Biotechnology Co., Ltd
-
- Sodium thiomethoxide
5188-07-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Sodium thiomethoxide
5188-07-8
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
5188-07-8(Sodium thiomethoxide)Related Search:
SODIUM TETRATHIONATE DIHYDRATE
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METHANETHIOL SODIUM SALT
Sodium methanethiolate, 21% aqueous solution
Sodium me
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Sodium thiomethoxide, 15% in water
methanethiolate
SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM)
Sodium methylthiolate
Sodium thiomethylate
SODIUM METHYLMERCAPTAN
METHYL MERCAPTAN SODIUM SALT
SODIUM METHANETHIOLATE
SODIUM METHYL MERCAPTIDE
High purity Sodium thiomethoxide
5188-07-8
5188-7-8
1201-10-8
1201108
CH3NaS
CH3SNa
Building Blocks
Na (Sodium) Compounds (excluding simple sodium salts)
Typical Metal Compounds
Classes of Metal Compounds
Sulfur Compounds
Thiol/Mercaptan Salts
Organic Building Blocks
Classes of Metal Compounds
Na (Sodium) Compounds (excluding simple sodium salts)
Typical Metal Compounds
API
Aliphatics
Sulfur & Selenium Compounds