(S)-PBMC (PBMC)
- CAS No.
- 1352138-54-5
- Chemical Name:
- (S)-PBMC (PBMC)
- Synonyms
- (S)-PBMC (PBMC);Carbamic acid, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (1S)-1-phenylethyl ester
- CBNumber:
- CB14844418
- Molecular Formula:
- C26H30N2O4
- Molecular Weight:
- 434.53
- MDL Number:
- MOL File:
- 1352138-54-5.mol
Last updated:2023-04-23 13:52:06
| Boiling point | 584.6±50.0 °C(Predicted) |
|---|---|
| Density | 1.165±0.06 g/cm3(Predicted) |
| storage temp. | -20°C (des.) |
| solubility | Soluble in DMSO (up to 30 mg/ml). |
| pka | 9.17±0.10(Predicted) |
| form | oil |
| color | Light brown |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
(S)-PBMC (PBMC) Chemical Properties,Uses,Production
Description
PBMC (1352138-54-5) is a potent and selective blocker of TRPM8 channels. PBMC blocks both chemical and thermal activation of TRPM8.1?Reverses the menthol and cold-induced facilitation of the micturition reflex.2?PBMC represents a new lead for analgesic drugs based on blocking TRPM8.3
References
1) Knowlton et al. (2011), Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice; PLoS One, 6(9) e25894 2) Gardiner et al. (2014), The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist; Eur. J. Pharmacol., 740 398 3) Salat et al. (2013), Transient receptor potential channels – emerging novel drug targets for the treatment of pain; Curr. Med. Chem., 20 1409
(S)-PBMC (PBMC) Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-PBMC (PBMC) Suppliers
Global( 1)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Focus Biomolecules | -- | sales@focusbiomolecules.com | United States | 1284 | 58 |
| Supplier | Advantage |
|---|---|
| Focus Biomolecules | 58 |
1352138-54-5((S)-PBMC (PBMC))Related Search:
(S)-PBMC
(PBMC)
Carbamic acid, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (1S)-1-phenylethyl ester
1352138-54-5