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DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) structure

CAS No.: 53016-31-2

Chemical Name:: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)

Synonyms: RWJ 10553;BRN 4202099;levonorgestreloxime;D-Norgestrel 3-oxime;(-)-NorelgestroMin-d6;Desacetylnorgestimate;17-Deacylnorgestimate;Levonorgestrel 3-oxime;17-Deacetylnorgestimate;Norelgestromin (1468454)

CBNumber:: CB1500552

Molecular Formula:: C21H29NO2

Molecular Weight:: 327.46

MDL Number:: MFCD03695603

MOL File:: 53016-31-2.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Properties

Melting point	107-109°C
Boiling point	491.9±45.0 °C(Predicted)
Density	1.23±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMF: 11 mg/ml; DMSO: 10 mg/ml; Ethanol: 12 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form	A solid
pka	12.22±0.60(Predicted)
color	White to off-white
CAS DataBase Reference	53016-31-2
FDA UNII	R0TAY3X631

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS08

Signal word

Danger

Hazard statements

H351-H360

Precautionary statements

P201-P308+P313

HS Code

2937230000

NFPA 704

	0
3		0

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	1468454	Deacetylnorgestimate	53016-31-2	200mg	$710	2024-03-01	Buy
Sigma-Aldrich	1471958	Deacetylnorgestimate	53016-31-2	25mg	$1240	2022-05-15	Buy
TRC	D288721	(E/Z)-17-Deacetylnorgestimate	53016-31-2	250mg	$1260	2021-12-16	Buy
American Custom Chemicals Corporation	API0000144	17-DESACETYL NORGESTIMATE 95.00%	53016-31-2	100MG	$1732.5	2021-12-16	Buy
ChemScene	CS-4097	NorgestimatemetaboliteNorelgestromin 99.79%	53016-31-2	50mg	$720	2021-12-16	Buy

Product number	Packaging	Price	Buy
1468454	200mg	$710	Buy
1471958	25mg	$1240	Buy
D288721	250mg	$1260	Buy
API0000144	100MG	$1732.5	Buy
CS-4097	50mg	$720	Buy

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Chemical Properties,Uses,Production

Description

Ortho Evra@ is the first birth control transdermal patch and contains a combination of norelgestromin and ethinylestradiol. The patch can be applied to the buttocks, lower abdomen, upper torso or arms; changed weekly for 3 weeks, followed by a patch-free week. Norelgestromin is the active metabolite produced following oral administration of norgestimate, the progestin component of the contraceptive, Ortho-Cyclen^?. The half-life value of norelgestromin was approximately 28 h. Following application, norelgestromin rapidly appeared in the serum, reached a plateau by approximately 48h and was maintained at an approximate steady state throughout the wear period. Hepatic metabolites of norelgestromin included norgestrel and various hydroxylated and conjugated metabolites that were eliminated by renal and fecal pathways. Ortho Evra produced ovarian suppression and cycle control. It was significantly more effective in suppressing follicular development than the leading oral contraceptive Triphasil^? (ethinyl estradiol/levomorgestrel); was as effective in preventing pregnancies and had similar tolerability profile. The patch offers 99% efficacy when used appropriately, as shown by three clinical trials. However, a statistically significantly greater proportion of pregnancies occurred among women weighing 90 kg or more. Ortho Evra^? was well tolerated, with 2.6% of women discontinuing treatment due to mild to moderate reactions at the site of application. Thus, the patch combined the efficacy of oral contraceptives with the convenience of just once-weekly dosing.

Chemical Properties

White Solid

Originator

Johnson & Johnson (USA)

Uses

E/Z-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.

Definition

ChEBI: Norelgestromin is a steroid. It derives from a hydride of an estrane.

brand name

ORTHOEVRA (R. W. Johnson); EVRA (R. W. Johnson) Note— Norelgestromin has appeared in the literature as 17- deacylnorgestimate.

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Preparation Products And Raw materials

Raw materials

Preparation Products

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Suppliers

Global( 60)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Guangzhou Tosun Pharmaceutical Ltd	+86-020-61855200-902 +8618124244216	info@upharm.cn	China	828	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2123	70
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50

Supplier	Advantage
TargetMol Chemicals Inc.	58
Nanjing Doge Biomedical Technology Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	58
Guangzhou Tosun Pharmaceutical Ltd	58
Amadis Chemical Company Limited	58
J & K SCIENTIFIC LTD.	76
LGM Pharma	70
Chemsky（shanghai）International Co.,Ltd.	50

View Lastest Price from DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Norgestimate metabolite Norelgestromin 53016-31-2	US $43.00-158.00 / mg		99.64%	10g	TargetMol Chemicals Inc.

Norgestimate metabolite Norelgestromin
53016-31-2
US $43.00-158.00 / mg
99.64%
TargetMol Chemicals Inc.

53016-31-2(DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE))Related Search:

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Norgestrel DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)

1of3

(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one OxiMe (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one-d6 OxiMe (-)-NorelgestroMin-d6 (17alpha)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime (E)- and (Z)-17-Deacetylnorgestimate mixture Norgestimate metabolite Norelgestromin 17-Desacetyl Norgestimate ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Deacetylnorgestimate (Mixture of (E)- And (Z)-17-Deacetyl Norgestimate) (17R)-13-Ethyl-17-hydroxy-18,19-dinor-pregna-4-ene-20-yne-3-oneoxime [17R,(+)]-17-Hydroxy-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one oxime [17R,(+)]-17-Hydroxy-13-ethyl-18,19-dinorpregna-4-ene-20-yne-3-oneoxime Desacetylnorgestimate DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) ,10-alpha,13-alpha,14-beta)- 18,19-dinorpregn-4-en-20-yn-3-one,13-ethyl-17-hydroxy-,oxime,(8-alpha,9-beta levonorgestreloxime 17-Deacetylnorgestimate (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Oxime 18-Methylnorethindrone oxime BRN 4202099 D-Norgestrel 3-oxime Levonorgestrel 3-oxime RWJ 10553 13-ETHYL-17_-HYDROXY-18,19-DINORPREGN-4-EN-20-YN-3-ONE OXIME 17-Desacetyl Norgestimate Solution, 100ppm 17-Desacetyl Norgestimate (Mixture of Isomers) 17-Deacylnorgestimate 17-Desacetyl Norgestimate-d7 (Mixture ofIsomers) (Norelgestromin-d7) 17-Desacetyl Norgestimate (Mixture of Isomers) (Norelgestromin) 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, oxime, (17α)- (E/Z)-17-Deacetylnorgestimate 17-Desacetyl NorgestimateQ: What is 17-Desacetyl Norgestimate Q: What is the CAS Number of 17-Desacetyl Norgestimate Q: What is the storage condition of 17-Desacetyl Norgestimate Q: What are the applications of 17-Desacetyl Norgestimate Norelgestromin (1468454) Deacetylnorgestimate ((E)- and (Z)-17-deacetyl norgestimate mixture) (1471958) Deacetylnorgestimate (Mixture of (E)- And (Z)) Drug Metabolite,inhibit,Inhibitor,Norgestimate metabolite Norelgestromin Deacetylnorgestimate ((E)- and (Z)-17-deacetyl norgestimate mixture) (8R,9S,10R,13S,14S,17R,E)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one oxime Deacetylnorgestimate (25 mg) ((E)- and (Z)-17-deacetyl norgestimate mixture) (PLANNED TO BE DISCONTINUED) Norgestimate metabolite Norelgestromin (mixture of isomers) 53016-31-2 Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Steroids