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ChemicalBook >> CAS DataBase List >>YKL-06-062

YKL-06-062

YKL-06-062 Structure
YKL-06-062 structure
CAS No.
2172617-16-0
Chemical Name:
YKL-06-062
Synonyms
YKL-06-062;YKL06062,YKL 06 062;YKL-06-062, 10 mM in DMSO;1-Cyclohexyl-3-(2,6-dimethylphenyl)-7-((4-(4-methylpiperazin-1-yl)phenyl)amino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one;Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclohexyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-
CBNumber:
CB15821395
Molecular Formula:
C31H39N7O
Molecular Weight:
525.69
MDL Number:
MFCD32263406
MOL File:
2172617-16-0.mol
Last updated:2025-04-18 09:51:42
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YKL-06-062 Properties

Boiling point 706.2±70.0 °C(Predicted)
Density 1.229±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 7.90±0.42(Predicted)
color Light yellow to yellow

YKL-06-062 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0103765 YKL-06-062 >98.0% 2172617-16-0 5mg $385 2021-12-16 Buy
ChemScene CS-0103765 YKL-06-062 >98.0% 2172617-16-0 10mg $655 2021-12-16 Buy
Product number Packaging Price Buy
CS-0103765 5mg $385 Buy
CS-0103765 10mg $655 Buy

YKL-06-062 Chemical Properties,Uses,Production

Description

YKL-06-062 is a second-generation SIK inhibitor. YKL 06-062 induces significant pigmentation after 8 days of treatment (1×/day). YKL 06-062 did not require mechanical application (rubbing) to induce significant human epidermal darkening. YKL-06-062 induces not only synthesis of melanin but also melanosomal maturation, export, and localization features, even after import into keratinocytes.

Uses

YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM for SIK1, SIK2 and SIK3, respectively[1].

References

[1] Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184. DOI:10.1016/j.celrep.2017.05.042

YKL-06-062 Preparation Products And Raw materials

Raw materials

Preparation Products

YKL-06-062 Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32202 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 998 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4348 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62072 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24683 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
ShangHai ChuanQian Chemcial Technique Centre 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from YKL-06-062 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
YKL-06-062 pictures 2024-11-19 YKL-06-062
2172617-16-0
 US $93.00-372.00 / mg 99.95% 10g TargetMol Chemicals Inc.
  • YKL-06-062 pictures
  • YKL-06-062
    2172617-16-0
  • US $93.00-372.00 / mg
  • 99.95%
  • TargetMol Chemicals Inc.

2172617-16-0(YKL-06-062)Related Search:

YKL 06-061 YKL-05-099 YKL-5-124
YKL-06-062 Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclohexyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]- YKL06062,YKL 06 062 1-Cyclohexyl-3-(2,6-dimethylphenyl)-7-((4-(4-methylpiperazin-1-yl)phenyl)amino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one YKL-06-062, 10 mM in DMSO 2172617-16-0 C31H39N7O