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1H-1,2,4-Triazole-1-carboximidamide hydrochloride

1H-1,2,4-Triazole-1-carboximidamide hydrochloride structure

CAS No.: 19503-26-5

Chemical Name:: 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

Synonyms: 1H-1,2,4-triazole-1-carboxiMidaMide hydrochloride;NOLA-010;1H-1,2,4-TRI;TIMTEC-BB SBB004089;Methotrexate (Abitrexate);1-CARBAMIDINO-1,2,4-TRIAZOLE;1,2,4-triazole-1-carboximidamide;1H-1,2,4-Triazole-1-CarboxaMidine;1-AMIDINO-1,2,4-TRIAZOLE HYDROCHLORIDE;1H-1,2,4-triazole-1-carboximidamide HCl

CBNumber:: CB1711419

Molecular Formula:: C3H6ClN5

Molecular Weight:: 147.57

MDL Number:: MFCD03095468

MOL File:: 19503-26-5.mol

Last updated:2025-01-27 09:38:02

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1H-1,2,4-Triazole-1-carboximidamide hydrochloride Properties

Melting point	215-220 °C
storage temp.	Inert atmosphere,Room Temperature
Water Solubility	Soluble in water
form	powder to crystal
color	White to Almost white
BRN	9500271
InChI	InChI=1S/C3H5N5.ClH/c4-3(5)8-2-6-1-7-8;/h1-2H,(H3,4,5);1H
InChIKey	JDDXNENZFOOLTP-UHFFFAOYSA-N
SMILES	C(N1N=CN=C1)(N)=N.Cl
CAS DataBase Reference	19503-26-5
UNSPSC Code	12352200
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H317-H319-H412
Precautionary statements	P264-P280i-P301+P312a-P337+P313-P501a-P280-P301+P312+P330-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22-36-52/53-43
Safety Statements	26-36/37-61
RIDADR	2811
WGK Germany	3
HazardClass	6.1
PackingGroup	III
HS Code	29339900

1H-1,2,4-Triazole-1-carboximidamide hydrochloride price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T3124	1,2,4-Triazole-1-carboximidamide Hydrochloride >98.0%(T)	19503-26-5	1g	$16	2024-03-01	Buy
TCI Chemical	T3124	1,2,4-Triazole-1-carboximidamide Hydrochloride >98.0%(T)	19503-26-5	5g	$42	2024-03-01	Buy
Alfa Aesar	H60475	1H-1,2,4-Triazole-1-carboxamidine hydrochloride, 98%	19503-26-5	5g	$18.65	2024-03-01	Buy
Alfa Aesar	H60475	1H-1,2,4-Triazole-1-carboxamidine hydrochloride, 98%	19503-26-5	25g	$79.2	2024-03-01	Buy
TRC	T767418	1H-1,2,4-Triazole-1-carboximidamideHydrochloride	19503-26-5	100mg	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
T3124	1g	$16	Buy
T3124	5g	$42	Buy
H60475	5g	$18.65	Buy
H60475	25g	$79.2	Buy
T767418	100mg	$75	Buy

1H-1,2,4-Triazole-1-carboximidamide hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White crystalline

Uses

[1,2,4]Triazole-1-carboxamidine is an intermediate used in the synthesis of peramivir (P285500), a neuraminidase inhibitor developed as an antiviral agent for the treatment of influenza.

Synthesis

1H-1,2,4-Triazole-1-carboxamidine hydrochloride is prepared by the reaction of dicyandiamide and 1,2,4-Triazole. The steps are as follows:
Dissolve the compound (19.7 g, 0.29 mol) in 20 ml of tetrahydrofuran, and the temperature was raised to 70℃. A solution of dicyandiamide (20 g, 0.24 mol) was added and a solution of 4 mol / L HCl in tetrahydrofuran 27 g, 0.26 mol) at 70℃ for 2 h, the temperature was removed and cooled to room temperature. The solid was removed by filtration and 26.0 g was removed by filtration. The solvent was dried in vacuo at 45℃ to give a colorless oil which was recrystallized from methanol: dichloromethane = 2: 1 Of the mixed solution 50ml recrystallization, cooling crystallization, suction filter to get 6.2g solid, drying a total of 30.1g white powder. Yield 90.3%, purity 99,8%.
1H-1,2,4-Triazole-1-carboxamidine hydrochloride synthesis

1H-1,2,4-Triazole-1-carboximidamide hydrochloride Preparation Products And Raw materials

Raw materials

1,2,4-Triazole Ethanol Sodium chloride 1,4-Dioxane Hydrochloric acid

Cyanamide Sulfuric acid

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Preparation Products

1H-1,2,4-Triazole-1-carboximidamide hydrochloride Suppliers

Global( 227)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sinopharm International Guangzhou Ltd.	+86-2038033341 +86-18520036739	zhuluqiang@sinopharm.com	China	76	58
Jinan Jianfeng Chemical Co., Ltd	+86-0531-88110457 +86-15562555968	info@pharmachemm.com	China	342	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21631	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29863	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

Supplier	Advantage
Sinopharm International Guangzhou Ltd.	58
Jinan Jianfeng Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 1H-1,2,4-Triazole-1-carboximidamide hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-03-26	1H-1,2,4-Triazole-1-carboximidamide hydrochloride 19503-26-5	US $0.00-0.00 / kg	1kg	99%min	20ton	Jinan Jianfeng Chemical Co., Ltd
2025-03-26	1H-1,2,4-Triazole-1-carboximidamide hydrochloride 19503-26-5	US $0.00 / KG	1KG	99%MIN	20TON	Jinan Jianfeng Chemical Co., Ltd
2022-10-01	1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHYDROCHLORIDE 19503-26-5	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

1H-1,2,4-Triazole-1-carboximidamide hydrochloride
19503-26-5
US $0.00-0.00 / kg
99%min
Jinan Jianfeng Chemical Co., Ltd

1H-1,2,4-Triazole-1-carboximidamide hydrochloride
19503-26-5
US $0.00 / KG
99%MIN
Jinan Jianfeng Chemical Co., Ltd

1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHYDROCHLORIDE
19503-26-5
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

19503-26-5(1H-1,2,4-Triazole-1-carboximidamide hydrochloride)Related Search:

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1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHYDROCHLORIDE 1-CARBAMIDINO-1,2,4-TRIAZOLE 1H-1,2,4-Triazole-1-carboxamidine monohydrochloride ,98.5% 1-AMIDINO-1,2,4-TRIAZOLE HYDROCHLORIDE TIMTEC-BB SBB004089 1h-1,2,4-triazole-1-carboxamidinehydrochloride 1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHY (1H)-1,2,4-Triazole-1-carboxamidineHClpurum (1H)-1,2,4-Triazole-1-carboxamidinemonohydrochloridepurum 1-amidino-1h-1,2,4-triazole hydrochloride 1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHY DROCHLORIDE PURUM 98+% 1H-1,2,4-Triazole-1-CarboxaMidine Methotrexate (Abitrexate) 1H-1,2,4-Triazole-1-carboxaMidine Monohydrochloride ,98% [1,2,4]Triazole-1-carboxaMidine Hydrochloride 1,2,4-Triazole-1-carboximidamide Hydrochloride 1H-1,2,4-Triazole-1-carboxamidine hydrochloride≥ 98%(Titration) 1-Carbamimidoyl-1,2,4-triazole Hydrochloride 1H-1,2,4-Triazole-1-carboximidamide, hydrochloride (1:1) 1-Amidino-1,2,4-triazole monohydrochloride NOLA-010 1H-1,2,4-TRI TIANFU-CHEM - 1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHYDROCHLORIDE 1,2,4-triazole-1-carboximidamide 1H-1,2,4-triazole-1-carboxiMidaMide hydrochloride 1H-1,2, 4-triazol-1-methylamidine monohydrochloride 1H-1,2,4-triazole-1-carboximidamide HCl 1H-1,2,4-Triazole-1-carboxamidine hydrochloride 19503-26-5 C3H6ClN5 C3H5N5HCl C3H5N5ClH Guanidine Protection/Guanidinylation Peptide Synthesis Specialty Synthesis