ChemicalBook >> CAS DataBase List >>SCH 58261
SCH 58261
- CAS No.
- 160098-96-4
- Chemical Name:
- SCH 58261
- Synonyms
- CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
- CBNumber:
- CB8497477
- Molecular Formula:
- C18H15N7O
- Molecular Weight:
- 345.36
- MDL Number:
- MFCD00933778
- MOL File:
- 160098-96-4.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
Melting point | 223 °C |
---|---|
Density | 1.54±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | DMSO: >10 mg/mL, soluble |
pka | 2.78±0.30(Predicted) |
form | solid |
color | off-white |
FDA UNII | 4309023MAH |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2934.99.3000 | |||||||||
NFPA 704 |
|
SCH 58261 price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S4568 | SCH 58261 ≥98% (HPLC), solid | 160098-96-4 | 5mg | $200 | 2024-03-01 | Buy |
Sigma-Aldrich | S4568 | SCH 58261 ≥98% (HPLC), solid | 160098-96-4 | 25mg | $304.8 | 2024-03-01 | Buy |
TCI Chemical | C3599 | SCH 58261 | 160098-96-4 | 5MG | $145 | 2024-03-01 | Buy |
TCI Chemical | C3599 | SCH 58261 | 160098-96-4 | 25MG | $532 | 2024-03-01 | Buy |
Cayman Chemical | 19676 | SCH 58261 ≥98% | 160098-96-4 | 1mg | $32 | 2024-03-01 | Buy |
SCH 58261 Chemical Properties,Uses,Production
Uses
SCH 58261 is a potent and selective A2A adenosine receptor antagonist.
Definition
ChEBI: LSM-3822 is a member of triazolopyrimidines.
Biological Activity
Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.
Biochem/physiol Actions
SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.
storage
Store at RT
SCH 58261 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 109)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from SCH 58261 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2020-03-06 | 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
160098-96-4
|
US $2.00 / g | 1g | 95~99.9% | 5KG | Career Henan Chemical Co |
-
- 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
160098-96-4
- US $2.00 / g
- 95~99.9%
- Career Henan Chemical Co
160098-96-4(SCH 58261)Related Search:
SCH54292
7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2)
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE
R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride
6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide
1of2
7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine
CS-2187
SCH-58261;SCH 58261
4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
Butanoicacid,4-bromo-5-oxo-,ethylester
Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor
160098-96-4
C18H15N7O
Adenosine receptor