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SCH 58261

SCH 58261 structure

CAS No.: 160098-96-4

Chemical Name:: SCH 58261

Synonyms: CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine

CBNumber:: CB8497477

Molecular Formula:: C18H15N7O

Molecular Weight:: 345.36

MDL Number:: MFCD00933778

MOL File:: 160098-96-4.mol

MSDS File:: SDS

Last updated:2024-11-09 19:38:33

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SCH 58261 Properties

Melting point	223 °C
Density	1.54±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	DMSO: >10 mg/mL, soluble
pka	2.78±0.30(Predicted)
form	solid
color	off-white
FDA UNII	4309023MAH

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

WGK Germany

HS Code

2934.99.3000

NFPA 704

	0
2		0

SCH 58261 price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S4568	SCH 58261 ≥98% (HPLC), solid	160098-96-4	5mg	$200	2024-03-01	Buy
Sigma-Aldrich	S4568	SCH 58261 ≥98% (HPLC), solid	160098-96-4	25mg	$304.8	2024-03-01	Buy
TCI Chemical	C3599	SCH 58261	160098-96-4	5MG	$145	2024-03-01	Buy
TCI Chemical	C3599	SCH 58261	160098-96-4	25MG	$532	2024-03-01	Buy
Cayman Chemical	19676	SCH 58261 ≥98%	160098-96-4	1mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
S4568	5mg	$200	Buy
S4568	25mg	$304.8	Buy
C3599	5MG	$145	Buy
C3599	25MG	$532	Buy
19676	1mg	$32	Buy

SCH 58261 Chemical Properties,Uses,Production

Uses

SCH 58261 is a potent and selective A2A adenosine receptor antagonist.

Definition

ChEBI: LSM-3822 is a member of triazolopyrimidines.

Biological Activity

Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.

Biochem/physiol Actions

SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.

storage

Store at RT

SCH 58261 synthesis

Synthesis of SCH 58261 from Furan-2-carbohydrazide

SCH 58261 Preparation Products And Raw materials

Raw materials

5-Amino-1-phenethyl-1H-pyrazole-4-carbonitrile Furan-2-carbohydrazide Cyanamide

Preparation Products

SCH 58261 Suppliers

Global( 110)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29814	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32077	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38468	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58

View Lastest Price from SCH 58261 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-08	SCH 58261 160098-96-4	US $34.00-77.00 / mg		99.75%	10g	TargetMol Chemicals Inc.
	2020-03-06	7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 160098-96-4	US $2.00 / g	1g	95~99.9%	5KG	Career Henan Chemical Co

SCH 58261
160098-96-4
US $34.00-77.00 / mg
99.75%
TargetMol Chemicals Inc.

7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
160098-96-4
US $2.00 / g
95~99.9%
Career Henan Chemical Co

SCH 58261 Spectrum

SCH 58261(160098-96-4)¹HNMR

160098-96-4(SCH 58261)Related Search:

SCH54292 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2) 2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride 6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide

SCH772984 2-PROPYL-2H-PYRAZOL-3-YLAMINE 4-METHYL-2-PROPYL-2 H-PYRAZOL-3-YLAMINE SCH 58261 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

1of2

7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine CS-2187 SCH-58261;SCH 58261 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine Butanoicacid,4-bromo-5-oxo-,ethylester Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor 160098-96-4 C18H15N7O Adenosine receptor