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ChemicalBook >> CAS DataBase List >>Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester

Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester

Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Structure
Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester structure
CAS No.
145119-18-2
Chemical Name:
Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester
Synonyms
Boc-NH-PEG1-C2-Boc;N-Boc-PEG-t-butyl ester;t-Butyl 3-(2-N-Boc-aminoethoxy)propanoate;tert-butyl 3-(2-(tert-butoxycarbonyl)ethoxy)propanoate;Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester
CBNumber:
CB18183283
Molecular Formula:
C14H27NO5
Molecular Weight:
289.37
MDL Number:
MFCD29764404
MOL File:
145119-18-2.mol
Last updated:2024-03-25 20:41:16
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Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Properties

Boiling point 384.2±22.0 °C(Predicted)
Density 1.026±0.06 g/cm3(Predicted)
pka 12.22±0.46(Predicted)

Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Chemical Properties,Uses,Production

Biological Activity

N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Shanghai Aizikang Pharmaceutical Research Co., Ltd 18721109360 306685371@qq.com China 1854 58
Supplier Advantage
Xian confluore Biological Technology Co., Ltd. 		58
Xi'an Confluore Biological Technology Co., Ltd. 58
Shanghai Aizikang Pharmaceutical Research Co., Ltd 58

View Lastest Price from Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-NH-PEG1-C2-Boc pictures 2024-03-25 Boc-NH-PEG1-C2-Boc
145119-18-2
 US $0.00 / g 1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.
  • Boc-NH-PEG1-C2-Boc pictures
  • Boc-NH-PEG1-C2-Boc
    145119-18-2
  • US $0.00 / g
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.
Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester t-Butyl 3-(2-N-Boc-aminoethoxy)propanoate N-Boc-PEG-t-butyl ester Boc-NH-PEG1-C2-Boc tert-butyl 3-(2-(tert-butoxycarbonyl)ethoxy)propanoate 145119-18-2