ChemicalBook >> CAS DataBase List >>7-Hydroxycoumarin
7-Hydroxycoumarin
- CAS No.
- 93-35-6
- Chemical Name:
- 7-Hydroxycoumarin
- Synonyms
- UMBELLIFERONE;7-Hydroxycoumarine;Z-LIGUSTILIDE;SKIMMETIN;7-Hydroxy-2H-chromen-2-one;UMBELLIFERON;Dichrin A;7 HC;HYDRANGIN;Hydramgin
- CBNumber:
- CB1854673
- Molecular Formula:
- C9H6O3
- Molecular Weight:
- 162.14
- MDL Number:
- MFCD00006878
- MOL File:
- 93-35-6.mol
- MSDS File:
- SDS
Last updated:2024-11-21 15:02:05
| Melting point | 230 °C (dec.)(lit.) |
|---|---|
| Boiling point | 248.82°C (rough estimate) |
| Density | 1.2599 (rough estimate) |
| refractive index | 1.5380 (estimate) |
| storage temp. | 2-8°C |
| solubility | dioxane: soluble |
| pka | 7.11(at 25℃) |
| form | Powder and Agglomerate |
| color | Off-white to beige-brownish |
| PH Range | Non/ uorescence (6.5) to blue / uorescence (8.0) |
| Odor | develops odor of coumarin on heating |
| Water Solubility | 1 g/100 mL (100 ºC) |
| λmax | 320nm |
| Merck | 14,9847 |
| BRN | 127683 |
| Major Application | Fluorescent brighteners, fungicides, cosmetics, antitrypanosomal, antileishmanial activities, antifungal, antibacterial, antiinflammatory, antiHIV, detection of microorganisms, treatment of impaired neurotransmission disorders, Alzheimer’s disease, vascular and lymphatic edema cancer, early diagnosis of stroke, dental material, drug-coated coronary stent system |
| InChIKey | ORHBXUUXSCNDEV-UHFFFAOYSA-N |
| LogP | 1.580 (est) |
| Indirect Additives used in Food Contact Substances | UMBELLIFERONE |
| FDA 21 CFR | 175.105 |
| CAS DataBase Reference | 93-35-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 60Z60NTL4G |
| NIST Chemistry Reference | 7-Hydroxycoumarin(93-35-6) |
| EPA Substance Registry System | Umbelliferone (93-35-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GN6820000 | |||||||||
| HS Code | 29322980 | |||||||||
| Toxicity | LD50 intravenous in mouse: 450mg/kg | |||||||||
| NFPA 704 |
|
7-Hydroxycoumarin price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93979 | Umbelliferone suitable for fluorescence indicator, ≥98.0% (HPLC) | 93-35-6 | 25g | $111 | 2024-03-01 | Buy |
| Sigma-Aldrich | 54826 | Umbelliferone analytical standard | 93-35-6 | 50mg | $140 | 2024-03-01 | Buy |
| TCI Chemical | H0236 | Umbelliferone >98.0%(GC) | 93-35-6 | 5g | $31 | 2024-03-01 | Buy |
| TCI Chemical | H0236 | Umbelliferone >98.0%(GC) | 93-35-6 | 25g | $60 | 2024-03-01 | Buy |
| Alfa Aesar | L04082 | 7-Hydroxycoumarin, 98% | 93-35-6 | 25g | $68.7 | 2024-03-01 | Buy |
7-Hydroxycoumarin Chemical Properties,Uses,Production
Chemical Properties
Light Brownish Powder
Uses
antifungal, phytoalexin
Uses
A metabolite of Coumarin. The aglucon of skimmin. Present in many plants
Uses
7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.
Uses
In sunscreen lotions and creams; as intracellular and pH sensitive fluorescent indicator and blood-brain barrier probe.
Definition
ChEBI: A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.
General Description
Umbelliferone is a naturally occurring coumarin, present in a variety of medicinal plants from the Apiaceae (Umbelliferae) family and also in plants from other families such as mouse-ear hawkweed.
Purification Methods
It crystallises from water (m 232-232.2o) or EtOH (m 232o). It sublimes at 160o/0.001mm. Fluorescence: Em max 452nm/Exc 325nm in 50% EtOH. [Beilstein 18 H 27, 18 I 306, 18 II 16, 18 III/IV 294, 18/1 V 386.]
7-Hydroxycoumarin Preparation Products And Raw materials
Raw materials
Preparation Products
[(2-OXO-2H-CHROMEN-7-YL)OXY]ACETIC ACID
8-ACETYL-6-HYDROXY-7-METHOXY-CHROMEN-2-ONE
7-ACETOXYCOUMARIN
CHEMBRDG-BB 6088138
FRAXIDIN
7-Methoxycoumarin
7-Ethoxycoumarin
7,8-Dihydroxycoumarin
2-(2-OXO-2H-CHROMEN-7-YLOXY)-PROPIONIC ACID
8-ACETYL-7-HYDROXYCOUMARIN
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Global( 561)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| R&D Scientific Inc. | +1-2266000236 | sales@rdscientific.com | Canada | 1609 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20286 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 1056 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18775 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
View Lastest Price from 7-Hydroxycoumarin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-28 | 7-Hydroxycoumarin
93-35-6
|
US $10.00 / kg | 1kg | 99% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-11-28 | 7-Hydroxycoumarin
93-35-6
|
US $79.00-38.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2024-11-19 | Umbelliferone
93-35-6
|
US $30.00 / mg | 98.3% | 10g | TargetMol Chemicals Inc. |
-
- 7-Hydroxycoumarin
93-35-6
- US $10.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- 7-Hydroxycoumarin
93-35-6
- US $79.00-38.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Umbelliferone
93-35-6
- US $30.00 / mg
- 98.3%
- TargetMol Chemicals Inc.
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HOC6H3CHCHCOO