ChemicalBook >> CAS DataBase List >>2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) structure

CAS No.: 57781-14-3

Chemical Name:: 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

Synonyms: Topicon;THS 201;Haloart;Ccris 2685;Einecs 260-951-4;halopredone acetate;Halopredone 17,21-diacetate;17,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;17α,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione

CBNumber:: CB1902921

Molecular Formula:: C25H29BrF2O7

Molecular Weight:: 559.39

MDL Number:: MFCD00866011

MOL File:: 57781-14-3.mol

Last updated:2023-05-04 17:34:40

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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Properties

Melting point	290-292° (dec)
alpha	D24 -36° (c = 1 in chloroform)
Density	1.3611 (rough estimate)
refractive index	1.3760 (estimate)
FDA UNII	24NUL39JY1

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0002886	2-BROMO-6BETA,9-DIFLUORO-11BETA,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 17,21-DI(ACETATE) 95.00%	57781-14-3	5MG	$505.75	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0002886	5MG	$505.75	Buy

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Chemical Properties,Uses,Production

Originator

Topicon,Pierrel,Italy,1983

Uses

Anti-inflammatory (topical).

Definition

ChEBI: Halopredone acetate is an organic molecular entity.

Manufacturing Process

100 ml of a 70% hydrofluoric acid aqueous solution were cooled to -10°C in a polyethylene flask equipped with electromagnetic stirrer. 10 g of 2-bromo-6β- fluoro-17α,21-dihydroxy-9β, 11β-oxido-pregna-1,4-diene-3,20-dione-17,21- diacetate were added under stirring during 15 minutes. After 0.5 hour the reaction mixture was precipitated in water and ammonia. The solid was collected by filtration, washed with water and dried to a constant weight, giving about 9.5 g of 2-bromo-6β,9α-difluoro-11β,17α,21 -trihydroxypregna- 1,4-diene-3,20-dione-17,21-diacetate.

Therapeutic Function

Topical antiinflammatory

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Preparation Products And Raw materials

Raw materials

hydrogen fluoride 11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Hydrogen fluoride

Preparation Products

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9900	58

Supplier	Advantage
Shanghai T&W Pharmaceutical Co., Ltd.	58

57781-14-3(2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate))Related Search:

1-BROMO-4-METHYL-3-HEXENE halopredone 1,3-DIACETOXYACETONE 5-BROMO-2-METHYL-2-PENTENE 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

Haloart halopredone acetate 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6β,11β)- THS 201 Topicon 17,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione 17α,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione 17,21-Bis(acetyloxy)-2-bromo-6-beta,9-difluoro-11-beta-hydroxypregna-1,4-dien-3,20-dione 17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione Ccris 2685 Einecs 260-951-4 Halopredone 17,21-diacetate Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6beta,11beta)- 57781-14-3 C25H29BrF2O7