amphotalide
- CAS No.
- 1673-06-9
- Chemical Name:
- amphotalide
- Synonyms
- RP-6171;amphotalide;Schistomide;Amphothalide;2-[5-(4-aminophenoxy)pentyl]isoindole-1,3-dione;2-[5-(4-azanylphenoxy)pentyl]isoindole-1,3-dione;2-(5-(4-Aminophenoxy)pentyl)isoindoline-1,3-dione;2-[5-(4-aminophenoxy)pentyl]isoindoline-1,3-quinone;2-[5-(4-Aminophenoxy)pentyl]-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 2-[5-(4-aminophenoxy)pentyl]-
- CBNumber:
- CB1941229
- Molecular Formula:
- C19H20N2O3
- Molecular Weight:
- 324.378
- MDL Number:
- MFCD00866729
- MOL File:
- 1673-06-9.mol
| Melting point | 113-114° |
|---|---|
| FDA UNII | 95818EH730 |
amphotalide Chemical Properties,Uses,Production
Originator
Amphotalide,ZYF Pharm Chemical
Definition
ChEBI: Amphotalide is a member of phthalimides.
Manufacturing Process
A mixture of 5-phthalimidopentyl bromide (Drake and Garman, J.Amer. Chem.
Sec, 1949, 71, 2426) (296.0 g) and potassium p-nitrophenoxide (177.0 g) in
ethanol (1.5 L) was stirred mechanically, boiled under reflux for 20 h,
concentrated to half its volume, cooled and filtered. The product was washed
with water, dried and crystallised from acetone, giving 1-p-nitrophenoxy-5-
phthalimidopentane, melting point 123°-124°C.
The foregoing 1-p-nitrophenoxy-5-phthalimidopentane (100.0 g) in ethanol (1
L) was reduced by hydrogen over 2% of platinum oxide at 74°C/73 lb. per sq.
in. The filtered solution on cooling gave L-p-aminophenoxy-5-phthalimidopentane, melting point 111°-112° C (recrystallisation from
ethanol).
Therapeutic Function
Antischistosomal
amphotalide Preparation Products And Raw materials
amphotalide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10011 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Supplier | Advantage |
|---|---|
| Alchem Pharmtech,Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |