Methylophiopogonanone A
- CAS No.
- 74805-92-8
- Chemical Name:
- Methylophiopogonanone A
- Synonyms
- Methylophiopogonanone A;R-Methylophiopogonanone A;8-Methylophiopogonanone A;Methylophiopogonanone A -RM;Methylophiopogonanone A (MO-A);Methylophiopogonanone A, 10 mM in DMSO;Methylophiopogonanone A(R-Methylophiopogonanone A);3-(benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one;(3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one;(3R)-3-(1,3-Benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-4H-1-benzopyran-4-one
- CBNumber:
- CB21267822
- Molecular Formula:
- C19H18O6
- Molecular Weight:
- 342.34
- MDL Number:
- MFCD11111461
- MOL File:
- 74805-92-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Methylophiopogonanone A price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL84060 | Methylophiopogonanone A phyproof? Reference Substance | 74805-92-8 | 10MG | $514 | 2024-03-01 | Buy |
| Cayman Chemical | 30192 | Methylophiopogonanone A | 74805-92-8 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 30192 | Methylophiopogonanone A | 74805-92-8 | 10mg | $301 | 2024-03-01 | Buy |
| Cayman Chemical | 30192 | Methylophiopogonanone A | 74805-92-8 | 5mg | $169 | 2024-03-01 | Buy |
| Usbiological | 300629 | Methylophiopogonanone A | 74805-92-8 | 10mg | $450 | 2021-12-16 | Buy |
Methylophiopogonanone A Chemical Properties,Uses,Production
Description
Methylophiopogonanone A is a homoisoflavonoid that has been found in O. japonicus roots and has diverse biological activities. It increases the uptake of rosuvastatin (Item Nos. 12029 | 18813) and atorvastatin in HEK293T cells expressing human organic anion transporting polypeptide 1B1 (OATP1B1; EC50s = 11.33 and 6 μM, respectively). Methylophiopogonanone A scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals in cell-free assays. In vivo, methylophiopogonanone A (10 mg/kg) decreases body weight gain and reduces serum and hepatic lipid levels in a rat model of high-fat diet-induced hyperlipidemia. It also reduces infarct size and myocardial apoptosis in mouse model of ischemia-reperfusion injury induced by transient occlusion of the left anterior descending coronary artery.
Uses
Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties[1].
Definition
ChEBI: Methylophiopogonanone A is a homoflavonoid.
in vivo
Methylophiopogonanone A (MO-A;10 mg/kg/d, po) for 2 weeks) protects cardiac function following myocardial I/R injury[1].
target
MMP(e.g.TIMP)
References
[1] He F, et al. Methylophiopogonanone A suppresses ischemia/reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway. Acta Pharmacol Sin. 2016 Jun;37(6):763-71. DOI:10.1038/aps.2016.14
Methylophiopogonanone A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 953 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
View Lastest Price from Methylophiopogonanone A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Methylophiopogonanone A
74805-92-8
|
US $72.00-250.00 / mg | 99.78% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-04-12 | Methylophiopogonanone A
74805-92-8
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2023-02-24 | Methylophiopogonanone A
74805-92-8
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Methylophiopogonanone A
74805-92-8
- US $72.00-250.00 / mg
- 99.78%
- TargetMol Chemicals Inc.
-
- Methylophiopogonanone A
74805-92-8
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Methylophiopogonanone A
74805-92-8
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.