ChemicalBook >> CAS DataBase List >>4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
- CAS No.
- 112241-19-7
- Chemical Name:
- 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
- Synonyms
- 4-Succinimidyloxycarbonyl-α-Methyl-α-(2-Pyridyldithio)toluene;4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene;2,5-Dioxopyrrolidin-1-yl 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate;2,5-dioxopyrrolidin-1-yl 4-(1-(pyridin-2-yldisulfaneyl)ethyl)benzoate;Benzoic acid, 4-[1-(2-pyridinyldithio)ethyl]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB21374227
- Molecular Formula:
- C18H16N2O4S2
- Molecular Weight:
- 388.46
- MDL Number:
- MFCD00083161
- MOL File:
- 112241-19-7.mol
Last updated:2024-07-02 08:55:02
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 803472 | SMPT (4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene) | 112241-19-7 | 50MG | $484 | 2023-06-20 | Buy |
| TRC | S688098 | 4-Succinimidyloxycarbonyl-α-methyl-α-(2-pyridyldithio)toluene | 112241-19-7 | 10mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0103518 | SMPT | 112241-19-7 | 100mg | $460 | 2021-12-16 | Buy |
| Abosyn | 40-0198 | 2,5-Dioxopyrrolidin-1-yl4-(1-(pyridin-2-yldisulfanyl)ethyl)benzoate >95% | 112241-19-7 | 250mg | $590 | 2021-12-16 | Buy |
| Alichem | 112241197 | 4-Succinimidyloxycarbonyl-alpha-methyl-alpha-(2-pyridyldithio)toluene | 112241-19-7 | 1g | $1088.78 | 2021-12-16 | Buy |
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Chemical Properties,Uses,Production
General Description
SMPT is a heterobifunctional sulfhydryl- and amine-reactive cross-linker. SMPT is used often for conjugating a toxin molecule to a monoclonal antibody directed against a cell-surface antigen. These immunotoxins produced with SMPT are highly potent as the cleavable disulfide imparts increased cytotoxicity compared to conjugates without a cleavable bond, such as those produced with SPDP. Also, next to the pyridine-2-thione in the spacer arm are a benzene ring and a methyl group adjacent to a carbon that hinders the disulfide bond, allowing exceptional conjugate stability in vivo. SMPT has the added benefit of being more stable to hydrolysis in aqueous solutions than other NHS cross-linkers.
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Preparation Products And Raw materials
Raw materials
Preparation Products
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Suppliers
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19918 | 55 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3994 | 55 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4824 | 58 |
View Lastest Price from 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene manufacturers
4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
Benzoic acid, 4-[1-(2-pyridinyldithio)ethyl]-, 2,5-dioxo-1-pyrrolidinyl ester
2,5-dioxopyrrolidin-1-yl 4-(1-(pyridin-2-yldisulfaneyl)ethyl)benzoate
2,5-Dioxopyrrolidin-1-yl 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate
4-Succinimidyloxycarbonyl-α-Methyl-α-(2-Pyridyldithio)toluene
112241-19-7