Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride Structure
6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride structure
CAS No.
230615-23-3
Chemical Name:
6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride
Synonyms
Varenicline HCl;Chantix hydrochloride;ChaMpix hydrochloride;CP 526555 hydrochloride;Varenicline hydrochloride;CP 526555 HYDROCHLORIDE; CHAMPIX HYDROCHLORIDE; CHANTIX HYDROCHLORIDE;7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline hydrochloride;5,8,14-TRIAZATETRACYCLO[10.3.1.0(2,11).0(4,9)]HEXADECA-2(11),3,5,7,9-PENT+;6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine hydrochloride;6,7,8,9-tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine Monohydrochloride
CBNumber:
CB21512571
Molecular Formula:
C13H14ClN3
Molecular Weight:
247.73
MDL Number:
MFCD11042277
MOL File:
230615-23-3.mol
Last updated:2024-10-28 23:16:16
Request For Quotation

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
color Light yellow to khaki
FDA UNII FW5Z3M5N2Y

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0828 Varenicline(Hydrochloride) 98.87% 230615-23-3 5mg $84 2021-12-16 Buy
Biosynth Carbosynth FV152325 Varenicline hydrochloride 230615-23-3 10mg $85 2021-12-16 Buy
ApexBio Technology B1141 VareniclineHydrochloride 230615-23-3 5mg $119 2021-12-16 Buy
ChemScene CS-0828 Varenicline(Hydrochloride) 98.87% 230615-23-3 10mg $120 2021-12-16 Buy
ApexBio Technology B1141 VareniclineHydrochloride 230615-23-3 10mg $189 2021-12-16 Buy
Product number Packaging Price Buy
CS-0828 5mg $84 Buy
FV152325 10mg $85 Buy
B1141 5mg $119 Buy
CS-0828 10mg $120 Buy
B1141 10mg $189 Buy

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride Chemical Properties,Uses,Production

Uses

Varenicline Hydrochloride is a useful nicotine binding inhibitor.

Biological Activity

varenicline hydrochloride is a partial agonist of α4β2 nicotinic receptor for smoking cessation [1].varenicline hydrochloride has been reported to potently inhibit nachr binding with the ki values of 0.12±0.02 nm and 0.14±0.01 nm for α6β2* nachr and α4β2* nachr, respectively in rat striatum, 0.13±0.01 nm and 0.19±0.11 nm forα6β2* nachr and α4β2* nachr, respectively in monkey striatum. in addition, varenicline hydrochloride has shown to be more potent in stimulating both α6β2* and α4β2* nachrs compared with nicotine with the ec50 values of 0.007 and 0.086μm, respectively in rat striatum [1].

References

[1] bordia t1, hrachova m, chin m, mcintosh jm, quik m. varenicline is a potent partial agonist at α6β2* nicotinic acetylcholine receptors in rat and monkey striatum. j pharmacol exp ther. 2012 aug;342(2):327-34. doi: 10.1124/jpet.112.194852. epub 2012 may 1.

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29814 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32072 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38465 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58
TargetMol Chemicals Inc. 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Varenicline Hydrochloride pictures 2024-10-28 Varenicline Hydrochloride
230615-23-3
 US $52.00-83.00 / mg 10g TargetMol Chemicals Inc.
6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride pictures 2019-12-23 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride
230615-23-3
 US $1.00 / ASSAYS 1ASSAYS 99.99% 200kg Career Henan Chemical Co

230615-23-3(6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride)Related Search:

Varenicline-d4 Dihydrochloride (Major) Varenicline Lactam Varenicline N-Glucoside Varenicline Carbamoyl β-D-Glucuronide 6,7-DIMETHYLQUINOXALINE
10-AZA-TRICYCLO[6.3.1.0]DODECA-2,4,6-TRIENE TOSYLATE 2,3,4,5-TETRAHYDRO-1H-1,5-METHANO-3-BENZAZEPINE HYDROCHLORIDE Varenicline 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride

1of2

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-,monohydrochloride (Varenicline Hcl) Varenicline hydrochloride 6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine hydrochloride 5,8,14-TRIAZATETRACYCLO[10.3.1.0(2,11).0(4,9)]HEXADECA-2(11),3,5,7,9-PENT+ 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-, hydrochloride (1:1) 7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline hydrochloride 6,7,8,9-tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine Monohydrochloride ChaMpix hydrochloride Chantix hydrochloride CP 526555 hydrochloride 6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine hydrochloride (Varenicline hydrochloride) CP 526555 HYDROCHLORIDE; CHAMPIX HYDROCHLORIDE; CHANTIX HYDROCHLORIDE Varenicline HCl 230615-23-3 C13H13N3HCl API intermediates