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ChemicalBook >> CAS DataBase List >>H-1152Glycyl, Dihydrochloride

H-1152Glycyl, Dihydrochloride

H-1152Glycyl, Dihydrochloride Structure
H-1152Glycyl, Dihydrochloride structure
CAS No.
913844-45-8
Chemical Name:
H-1152Glycyl, Dihydrochloride
Synonyms
Glycyl-H 1152 2HCl;Rho Kinase Inhibitor IV;Glycyl H-1152 hydrochloride;H-1152Glycyl, Dihydrochloride;(S)-Glycyl-H-1152 (hydrochloride);Glycyl H1152 hydrochloride,Glycyl H 1152 hydrochloride;(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride;(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride;2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride
CBNumber:
CB21564868
Molecular Formula:
C18H26Cl2N4O3S
Molecular Weight:
0
MDL Number:
MFCD09971082
MOL File:
913844-45-8.mol
Last updated:2024-10-23 13:36:13
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H-1152Glycyl, Dihydrochloride Properties

Melting point 190-192°C
storage temp. Refrigerator
solubility Methanol (Slightly), Water (Slightly)
form Solid
color Pale Yellow to Beige
Stability Hygroscopic
CAS DataBase Reference 913844-45-8

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS08
Signal word  Danger
Hazard statements  H225-H370
Precautionary statements  P210-P233-P240-P241-P242-P243-P260-P264-P270-P280-P303+P361+P353-P307+P311-P321-P370+P378-P403+P235-P405-P501
NFPA 704
3
0 0

H-1152Glycyl, Dihydrochloride price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13332 (S)-Glycyl-H-1152 (hydrochloride) ≥98% 913844-45-8 500μg $93 2024-03-01 Buy
Cayman Chemical 13332 (S)-Glycyl-H-1152 (hydrochloride) ≥98% 913844-45-8 1mg $176 2024-03-01 Buy
Cayman Chemical 13332 (S)-Glycyl-H-1152 (hydrochloride) ≥98% 913844-45-8 5mg $728 2024-03-01 Buy
Cayman Chemical 13332 (S)-Glycyl-H-1152 (hydrochloride) ≥98% 913844-45-8 10mg $1274 2024-03-01 Buy
Usbiological 013030 H-1152 Glycyl Dihydrochloride 913844-45-8 1mg $460 2021-12-16 Buy
Product number Packaging Price Buy
13332 500μg $93 Buy
13332 1mg $176 Buy
13332 5mg $728 Buy
13332 10mg $1274 Buy
013030 1mg $460 Buy

H-1152Glycyl, Dihydrochloride Chemical Properties,Uses,Production

Chemical Properties

Pale-Yellow Solid

Uses

A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.

Biological Activity

Glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride ((S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride ) that displays improved ROCKII selectivity. IC 50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μ M for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.

storage

room temperature (desiccate)

H-1152Glycyl, Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

H-1152Glycyl, Dihydrochloride Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216 info@yuhaochemical.com China 9387 52
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2782 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57423 58
BOC Sciences -- info@bocsci.com USA 0 65
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
VDM Biochemicals 64
Chemsky（shanghai）International Co.,Ltd. 50
Hangzhou Yuhao Chemical Technology Co., Ltd 52
AdooQ BioScience, LLC 58
Shanghai Hongye Biotechnology Co. Ltd 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
BOC Sciences 65

View Lastest Price from H-1152Glycyl, Dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Glycyl H-1152 hydrochloride pictures 2024-10-24 Glycyl H-1152 hydrochloride
913844-45-8
 US $1820.00-3180.00 / mg 10g TargetMol Chemicals Inc.

913844-45-8(H-1152Glycyl, Dihydrochloride)Related Search:

H-1152Glycyl, Dihydrochloride FASUDIL (S)-(+)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLYNYL)SULFONYL]HOMOPIPERAZINE
(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride 2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride (S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride (S)-Glycyl-H-1152 (hydrochloride) Glycyl-H 1152 2HCl Rho Kinase Inhibitor IV H-1152Glycyl, Dihydrochloride Glycyl H-1152 hydrochloride Glycyl H1152 hydrochloride,Glycyl H 1152 hydrochloride 913844-45-8 C18H26Cl2N4O3S All Inhibitors Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators Protein Kinase