ChemicalBook >> CAS DataBase List >>3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
- CAS No.
- 629664-81-9
- Chemical Name:
- 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
- Synonyms
- XL335;CS-899;Fxr 450;Way 362450;Unii-S6kdm312I5;WAY-362450 (XL335;Turofexorate isopropyl;WAY-362450 >=98% (HPLC);WAY362450 - FXR450 - XL335;XL335;TUROFEXORATE ISOPROPYL
- CBNumber:
- CB22484921
- Molecular Formula:
- C25H24F2N2O3
- Molecular Weight:
- 438.47
- MDL Number:
- MFCD13181507
- MOL File:
- 629664-81-9.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:52
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Properties
Boiling point | 617.3±55.0 °C(Predicted) |
---|---|
Density | 1.275 |
storage temp. | room temp |
solubility | DMSO : 25 mg/mL (57.02 mM; Need ultrasonic) |
form | powder |
pka | 16.49±0.60(Predicted) |
color | white to beige |
FDA UNII | S6KDM312I5 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P305+P351+P338 | |||||||||
NFPA 704 |
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3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PZ0267 | WAY-362450 ≥98% (HPLC) | 629664-81-9 | 5MG | $112 | 2023-06-20 | Buy |
Sigma-Aldrich | PZ0267 | WAY-362450 ≥98% (HPLC) | 629664-81-9 | 25MG | $451 | 2023-06-20 | Buy |
Cayman Chemical | 23350 | XL335 ≥98% | 629664-81-9 | 5mg | $97 | 2024-03-01 | Buy |
Cayman Chemical | 23350 | XL335 ≥98% | 629664-81-9 | 10mg | $175 | 2024-03-01 | Buy |
Cayman Chemical | 23350 | XL335 ≥98% | 629664-81-9 | 25mg | $385 | 2024-03-01 | Buy |
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Chemical Properties,Uses,Production
Definition
ChEBI: Turofexorate isopropyl is a member of indoles.
Biochem/physiol Actions
WAY-362450 is a potent and selective Farnesoid X receptor (FXR) agonist that lowers total plasma cholesterol (all lipoprotein species). WAY-362450 reduced the levels of high-density lipoprotein cholesterol (HDLc) in Cynomolgus monkeys, mice and hamsters. Apparently HDL lowering is achieved through increased transhepatic cholesterol efflux.
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 111)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32835 | 60 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49403 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29820 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
View Lastest Price from 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-12-27 | 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
629664-81-9
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
- 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
629664-81-9
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co
629664-81-9(3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester)Related Search:
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
Fxr 450
Turofexorate isopropyl
Turofexorate isopropyl [usan]
Unii-S6kdm312I5
Way 362450
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
isopropyl 3-(3,4-difluorobenzoyl)-1,1-diMethyl-1,2,3,6-tetrahydr
WAY362450 - FXR450 - XL335
XL335
Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxyla
(E)-isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
Turofexorate Isopropyl (XL335)
propan-2-yl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
WAY-362450 (XL335
Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carbox
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,4,5,5a,6,10b-octahydroazepino[4,5-b]indole-5-carboxylate
XL335;TUROFEXORATE ISOPROPYL
CS-899
XL335; WAY 362450; TUROFEXORATE ISOPROPYL; WAY-362450
Azepino[4,5-b]indole-5-carboxylic acid, 3-(3,4-difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethyl-, 1-methylethyl ester
WAY-362450 >=98% (HPLC)
Turofexorate isopropyl XL335 XL-335 WAY-362450 WAY362450
629664-81-9
Inhibitors
A farnesoid X receptor (FXR) agonist .