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S-EMCA

CAS No.
1199796-29-6
Chemical Name:
S-EMCA
Synonyms
S-EMCA;INT-777;CS-1212;INT777,INT 777;INT-777, S-EMCA;6α-Ethyl-23(S)-Methylcholic acid;6a-Ethyl-23(S)-methylcholic acid;Obeticholic Acid Impurity 49(S-EMCA);6alpha-Ethyl-23(S)-methylcholic acid;Acetylcysteine Impurity 49(D-Cysteine)
CBNumber:
CB22667494
Molecular Formula:
C27H46O5
Molecular Weight:
450.65114
MDL Number:
MFCD18837028
MOL File:
1199796-29-6.mol
MSDS File:
SDS
Last updated:2024-11-13 18:13:23

S-EMCA Properties

Melting point 150-152℃
Boiling point 602.8±55.0 °C(Predicted)
Density 1.128±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF:30.0(Max Conc. mg/mL);66.57(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:25.5(Max Conc. mg/mL);56.58(Max Conc. mM)
Ethanol:37.5(Max Conc. mg/mL);83.21(Max Conc. mM)
pka 4.80±0.21(Predicted)
form Powder
color White to yellow
FDA UNII UTD8BCW6B8

S-EMCA price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17678 INT-777 ≥95% 1199796-29-6 500μg $121 2024-03-01 Buy
Cayman Chemical 17678 INT-777 ≥95% 1199796-29-6 1mg $230 2024-03-01 Buy
TRC I666630 6α-Ethyl-23(S)-methylcholicAcid 1199796-29-6 25mg $2035 2021-12-16 Buy
ApexBio Technology B4672 INT-777 1199796-29-6 50mg $2250 2021-12-16 Buy
ChemScene CS-3199 INT-777 100.00% 1199796-29-6 100mg $2520 2021-12-16 Buy
Product number Packaging Price Buy
17678 500μg $121 Buy
17678 1mg $230 Buy
I666630 25mg $2035 Buy
B4672 50mg $2250 Buy
CS-3199 100mg $2520 Buy

S-EMCA Chemical Properties,Uses,Production

Uses

INT 777 is an inhibitor of TGR5 receptor, which is a transmembrane G protein-coupled receptor expressed in brown adipose tissue and muscle and activated by bile acid.

1227639-47-5
74-88-4
1199796-29-6
Synthesis of S-EMCA from Cholan-24-oic acid, 6-ethyl-3,7,12-tris(methoxymethoxy)-, methyl ester, (3α,5β,6α,7α,12α)- and Iodomethane

S-EMCA Suppliers

Global( 51)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32079 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38469 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7552 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3466 58
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4512 55
BOC Sciences 16314854226 info@bocsci.com United States 9923 65

View Lastest Price from S-EMCA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
INT-777 pictures 2024-11-13 INT-777
1199796-29-6
US $139.00-347.00 / mg 99.89% 10g TargetMol Chemicals Inc.
INT-777 pictures 2024-11-13 INT-777
1199796-29-6
US $139.00-347.00 / mg 99.89% 10g TargetMol Chemicals Inc.
  • INT-777 pictures
  • INT-777
    1199796-29-6
  • US $139.00-347.00 / mg
  • 99.89%
  • TargetMol Chemicals Inc.
  • INT-777 pictures
  • INT-777
    1199796-29-6
  • US $139.00-347.00 / mg
  • 99.89%
  • TargetMol Chemicals Inc.
6α-Ethyl-23(S)-Methylcholic acid INT-777 S-EMCA 6alpha-Ethyl-23(S)-methylcholic acid Cholane-23-carboxylic acid, 6-ethyl-3,7,12-trihydroxy-, (3α,5β,6α,7α,12α,23S)- INT-777, S-EMCA CS-1212 6a-Ethyl-23(S)-methylcholic acid INT777,INT 777 Obeticholic Acid Impurity 49(S-EMCA) Acetylcysteine Impurity 49(D-Cysteine) (2S,4R)-4-((3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-Ethyl-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylpentanoic acid (2S,4R)-4-[(1R,3aS,3bR,4R,5R,5aS,7R,9aS,9bS,11S,11aR)-5-ethyl-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-methylpentanoic acid 1199796-29-6