ChemicalBook >> CAS DataBase List >>Ro 25-6981 (Maleate)
Ro 25-6981 (Maleate)
- CAS No.
- 1312991-76-6
- Chemical Name:
- Ro 25-6981 (Maleate)
- Synonyms
- [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate salt;1-Piperidinepropanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, ( αR,βS)-, (2Z)-2-butenedioate (1:1)
- CBNumber:
- CB22677053
- Molecular Formula:
- C26H33NO6
- Molecular Weight:
- 455.55
- MDL Number:
- MFCD06798375
- MOL File:
- 1312991-76-6.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H400 | |||||||||
| Precautionary statements | P261-P273-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 36/37/38-50 | |||||||||
| Safety Statements | 26-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Ro 25-6981 (Maleate) price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0495 | Ro 25-6981 maleate salt ≥98% (HPLC) | 1312991-76-6 | 5mg | $159 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0495 | Ro 25-6981 maleate salt ≥98% (HPLC) | 1312991-76-6 | 25mg | $507 | 2024-03-01 | Buy |
| Cayman Chemical | 14578 | Ro 25-6981 (maleate) ≥98% | 1312991-76-6 | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 14578 | Ro 25-6981 (maleate) ≥98% | 1312991-76-6 | 10mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 14578 | Ro 25-6981 (maleate) ≥98% | 1312991-76-6 | 50mg | $820 | 2024-03-01 | Buy |
Ro 25-6981 (Maleate) Chemical Properties,Uses,Production
Uses
Ro 25-6981 maleate is a potent NMDA receptor antagonist.
Definition
ChEBI: Ro 25-6981 maleate is the maleic acid salt of Ro 25-6981. It is a potent and selective antagonist of GluN2B-containing NMDA receptors. It has a role as an anticonvulsant, an antidepressant, a neuroprotective agent and a NMDA receptor antagonist. It contains a Ro 25-6981(1+).
Biochem/physiol Actions
Ro 25-6981 maleate salt is a potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit with IC50 values of .009 μM for NR2B vs. 52 μM for NR2A subunits. Ro 25-6981 has been shown to have neuroprotectant effects and to reduce inflammatory and neuropathic pain in rodent models.
storage
Room temperature (desiccate)
Ro 25-6981 (Maleate) Preparation Products And Raw materials
Raw materials
Preparation Products
Ro 25-6981 (Maleate) Suppliers
Global( 32)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4309 | 55 |
[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate salt
1-Piperidinepropanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, ( αR,βS)-, (2Z)-2-butenedioate (1:1)
1312991-76-6
API