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ChemicalBook >> CAS DataBase List >> Ro 25-6981 (Maleate)

Ro 25-6981 (Maleate)

Ro 25-6981 (Maleate) price.
  • $57 - $2500
  • Product name: Ro 25-6981 (Maleate)
  • CAS: 1312991-76-6
  • MF: C26H33NO6
  • MW: 455.55
  • EINECS:
  • MDL Number:MFCD06798375
  • Synonyms:[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate salt;1-Piperidinepropanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, ( αR,βS)-, (2Z)-2-butenedioate (1:1)
17 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009850
  • Product descriptionRO 25-6981 MALEATE 95.00%
  • Packaging5MG
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14578
  • Product descriptionRo 25-6981 (maleate) ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14578
  • Product descriptionRo 25-6981 (maleate) ≥98%
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14578
  • Product descriptionRo 25-6981 (maleate) ≥98%
  • Packaging50mg
  • Price$820
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2012
  • Product descriptionRo25-6981Maleate 97.96%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2012
  • Product descriptionRo25-6981Maleate 97.96%
  • Packaging10mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2012
  • Product descriptionRo25-6981Maleate 97.96%
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2012
  • Product descriptionRo25-6981Maleate 97.96%
  • Packaging100mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003920
  • Product descriptionRo25-6981Maleate 98+%
  • Packaging5mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003920
  • Product descriptionRo25-6981Maleate 98+%
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003920
  • Product descriptionRo25-6981Maleate 98+%
  • Packaging50mg
  • Price$343
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003920
  • Product descriptionRo25-6981Maleate 98+%
  • Packaging100mg
  • Price$616
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9852
  • Product descriptionRo25-6981maleate >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9852
  • Product descriptionRo25-6981maleate >98%
  • Packaging1g
  • Price$2500
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0495
  • Product descriptionRo 25-6981 maleate salt ≥98% (HPLC)
  • Packaging5mg
  • Price$159
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0495
  • Product descriptionRo 25-6981 maleate salt ≥98% (HPLC)
  • Packaging25mg
  • Price$507
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0009850 RO 25-6981 MALEATE 95.00% 5MG $530 2021-12-16 Buy
Cayman Chemical 14578 Ro 25-6981 (maleate) ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 14578 Ro 25-6981 (maleate) ≥98% 10mg $166 2024-03-01 Buy
Cayman Chemical 14578 Ro 25-6981 (maleate) ≥98% 50mg $820 2024-03-01 Buy
ChemScene CS-2012 Ro25-6981Maleate 97.96% 5mg $96 2021-12-16 Buy
ChemScene CS-2012 Ro25-6981Maleate 97.96% 10mg $138 2021-12-16 Buy
ChemScene CS-2012 Ro25-6981Maleate 97.96% 50mg $480 2021-12-16 Buy
ChemScene CS-2012 Ro25-6981Maleate 97.96% 100mg $900 2021-12-16 Buy
Crysdot CD31003920 Ro25-6981Maleate 98+% 5mg $69 2021-12-16 Buy
Crysdot CD31003920 Ro25-6981Maleate 98+% 10mg $97 2021-12-16 Buy
Crysdot CD31003920 Ro25-6981Maleate 98+% 50mg $343 2021-12-16 Buy
Crysdot CD31003920 Ro25-6981Maleate 98+% 100mg $616 2021-12-16 Buy
DC Chemicals DC9852 Ro25-6981maleate >98% 250mg $1100 2021-12-16 Buy
DC Chemicals DC9852 Ro25-6981maleate >98% 1g $2500 2021-12-16 Buy
Sigma-Aldrich SML0495 Ro 25-6981 maleate salt ≥98% (HPLC) 5mg $159 2024-03-01 Buy
Sigma-Aldrich SML0495 Ro 25-6981 maleate salt ≥98% (HPLC) 25mg $507 2024-03-01 Buy

Properties

storage temp. :2-8°C
solubility :H2O: soluble2mg/mL (clear solution, warmed)
form :powder
color :white to beige
optical activity :[α]/D +15 to +22°, c = 1 in methanol

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively). Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons against glutamate toxicity and combined oxygen and glucose deprivation with IC50 values of 0.4 and 0.04 μM, respectively.