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Mal-PEG4-Val-Cit-PAB-PNP

CAS No.
2112738-09-5
Chemical Name:
Mal-PEG4-Val-Cit-PAB-PNP
Synonyms
Mal-PEG4-Val-Cit-PAB-PNP;4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl (4-nitrophenyl) carbonate;4-((17S,20S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate;L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
CBNumber:
CB23373644
Molecular Formula:
C40H53N7O15
Molecular Weight:
871.89
MDL Number:
MFCD30828694
MOL File:
2112738-09-5.mol
Last updated:2024-07-02 08:55:03

Mal-PEG4-Val-Cit-PAB-PNP Properties

solubility Soluble in DMSO, DMF
form Solid
color Light yellow to yellow

Mal-PEG4-Val-Cit-PAB-PNP price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23668 Mal-PEG4-Val-Cit-PAB-PNP 97% 2112738-09-5 100mg $950 2021-12-16 Buy
Iris Biotech GmbH ADC1210 Mal-PEG(4)-Val-Cit-PAB-PNP 2112738-09-5 100mg $1012.5 2021-12-16 Buy
Ambeed A763179 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate 95% 2112738-09-5 100mg $1242 2021-12-16 Buy
Ambeed A763179 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate 95% 2112738-09-5 250mg $2110 2021-12-16 Buy
Ambeed A763179 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate 95% 2112738-09-5 1g $5485 2021-12-16 Buy
Product number Packaging Price Buy
BP-23668 100mg $950 Buy
ADC1210 100mg $1012.5 Buy
A763179 100mg $1242 Buy
A763179 250mg $2110 Buy
A763179 1g $5485 Buy

Mal-PEG4-Val-Cit-PAB-PNP Chemical Properties,Uses,Production

Description

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups. PEG space improve compound's aqueous solubility. PNP is a good leaving group.

Biological Activity

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

Mal-PEG4-Val-Cit-PAB-PNP Preparation Products And Raw materials

Raw materials

Preparation Products

Mal-PEG4-Val-Cit-PAB-PNP Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 7287 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
Shanghai Huici Pharmaceutical Technology Co., LTD
+8618917134367 lixing@pharmahuici.com China 133 58
Shanghai Huici Pharmaceutical Technology Co., LTD
+8618917134367 lixing@pharmahuici.com China 133 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Zhengzhou Huiju Chemical Co., Ltd. 0371-55900031 18137872243 2853979815@qq.com China 10008 55

View Lastest Price from Mal-PEG4-Val-Cit-PAB-PNP manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mal-PEG4-Val-Cit-PAB-PNP pictures 2024-03-29 Mal-PEG4-Val-Cit-PAB-PNP
2112738-09-5
US $0.00 / mg 100mg >98.00% 100mg Xian confluore Biological Technology Co., Ltd.
Mal-PEG4-Val-Cit-PAB-PNP L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl (4-nitrophenyl) carbonate 4-((17S,20S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate 2112738-09-5 C40H53N7O15 Linker ADC LINKER