ChemicalBook >> CAS DataBase List >>DJ001
DJ001
- CAS No.
- 2161305-12-8
- Chemical Name:
- DJ001
- Synonyms
- DJ001;DJ-001,DJ001;2-Propen-1-one, 3-[(3-nitrophenyl)amino]-1-phenyl-, (2Z)-
- CBNumber:
- CB25848933
- Molecular Formula:
- C15H12N2O3
- Molecular Weight:
- 268.27
- MDL Number:
- MFCD32689599
- MOL File:
- 2161305-12-8.mol
Last updated:2023-05-18 11:31:13
| Boiling point | 417.7±45.0 °C(Predicted) |
|---|---|
| Density | 1.297±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml with warming) |
| form | solid |
| pka | -1.30±0.70(Predicted) |
| color | Yellow |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
DJ001 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0112268 | DJ001 99.59% | 2161305-12-8 | 5mg | $350 | 2021-12-16 | Buy |
| Axon Medchem | Axon3018 | DJ001-UCLA5483071 99% | 2161305-12-8 | 50mg | $467.5 | 2021-12-16 | Buy |
| ChemScene | CS-0112268 | DJ001 99.59% | 2161305-12-8 | 10mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-0112268 | DJ001 99.59% | 2161305-12-8 | 50mg | $1650 | 2021-12-16 | Buy |
| ChemScene | CS-0112268 | DJ001 99.59% | 2161305-12-8 | 100mg | $2250 | 2021-12-16 | Buy |
DJ001 Chemical Properties,Uses,Production
Description
DJ001 (2161306-12-8) is a potent and specific inhibitor of receptor type protein tyrosine phosphatase-sigma (PTPσ) IC50=1.54 μM and >10 μM for 20 other phosphatases.1? Promotes hematopoietic stem cell regeneration in vivo. In mice treated with 5-fluorouracil or irradiated, DJ001 promoted HSC regeneration accelerated hematologic recovery and improved survival. The mode of inhibition of PTPs is via non-competitive allosteric binding. Suppression of radiation-induced HSC apoptosis occurs via activation of Rho GTPase, Rac1 and induction of BCL-XL. Treatment of irradiated human HSCs with DJ001 promotes the regeneration of human HSCs capable of multilineage in vivo repopulation.1
References
References/Citations:
DJ001 Preparation Products And Raw materials
Raw materials
Preparation Products
DJ001 Suppliers
Global( 14)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 997 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7984 | 58 |
2161305-12-8(DJ001)Related Search:
DJ001
DJ-001,DJ001
2-Propen-1-one, 3-[(3-nitrophenyl)amino]-1-phenyl-, (2Z)-
2161305-12-8