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Cytidine 5’-monophosphate

Cytidine 5’-monophosphate Structure
Cytidine 5’-monophosphate structure
CAS No.
63-37-6
Chemical Name:
Cytidine 5’-monophosphate
Synonyms
CMP;CYTIDYLIC ACID;5'-CYTIDINE MONOPHOSPHATE;((2R,3S,4R,5R)-5-(4-aMino-2-oxopyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate;C-5-P;5'-CMP;C-5'-P;CMP.H2;3'-CMP;5'-CMPH2
CBNumber:
CB2700845
Molecular Formula:
C9H14N3O8P
Molecular Weight:
323.2
MDL Number:
MFCD00006544
MOL File:
63-37-6.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02
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Cytidine 5’-monophosphate Properties

Melting point ~222 °C (dec.)
Boiling point 678.1±65.0 °C(Predicted)
Density 2.15±0.1 g/cm3(Predicted)
refractive index 9.8 ° (C=1, 0.5mol/L Na2HPO4)
storage temp. 2-8°C
solubility Water (Slightly, Heated)
pka pK2:4.39(0);pK3:6.62(+1) (25°C)
form crystalline
color White
biological source synthetic
Water Solubility soluble
BRN 46982
InChI InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey IERHLVCPSMICTF-JDNPWWSISA-N
SMILES P(OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1O)(O)(O)=O
CAS DataBase Reference 63-37-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII F469818O25
EPA Substance Registry System 5'-Cytidylic acid (63-37-6)
UNSPSC Code 41116107
NACRES NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-37/39-36-26
WGK Germany  3
RTECS  HA3980000
F  10-21
HS Code  29349990
Toxicity LD50 intraperitoneal in mouse: > 1gm/kg
NFPA 704
0
1 0

Cytidine 5’-monophosphate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C1131 Cytidine 5′-monophosphate Sigma Grade, ≥99% (HPLC), synthetic, powder 63-37-6 1g $112 2024-03-01 Buy
Sigma-Aldrich 1162126 5′-Cytidylic acid United States Pharmacopeia (USP) Reference Standard 63-37-6 500mg $420 2024-03-01 Buy
TCI Chemical C1675 Cytidine 5'-Monophosphate >98.0%(HPLC) 63-37-6 1g $49 2024-03-01 Buy
TCI Chemical C1675 Cytidine 5'-Monophosphate >98.0%(HPLC) 63-37-6 5g $164 2024-03-01 Buy
Sigma-Aldrich C1131 Cytidine 5′-monophosphate Sigma Grade, ≥99% (HPLC), synthetic, powder 63-37-6 500mg $74.8 2024-03-01 Buy
Product number Packaging Price Buy
C1131 1g $112 Buy
1162126 500mg $420 Buy
C1675 1g $49 Buy
C1675 5g $164 Buy
C1131 500mg $74.8 Buy

Cytidine 5’-monophosphate Chemical Properties,Uses,Production

Description

Cytidine 5'-monophosphate, also known as 5'-CMP, is a nucleotide that is used as a monomer in RNA. 5'-CMP is a key intermediate in the preparation of several nucleotide derivatives and is widely used in food and pharmaceutical industries.

Chemical Properties

white crystalline powder

Uses

Cytidine 5′-monophosphate has been used in Raman spectroscopy studies.

Uses

A constituent of nucleic acids. It was isolated from yeast nucleic acid.

Production Methods

As a key intermediate in preparing several nucleotide derivatives, cytidine 5′-monophosphate (5′-CMP) is widely applied in food and pharmaceutical industries. Enzymatic synthesis of 5′-CMP is catalyzed by cytidine kinase (CK, EC 2.7.1.213), a type of nucleoside kinase that belongs to the PfkB family. Li et al. constructed a highly efficient biosynthesis system for manufacturing 5′-CMP in vitro. CK was used for the biotransformation of cytidine to 5′-CMP, while polyphosphate kinase (PPK) was coupled for adenosine triphosphate regeneration. Both CK and PPK were selected from extremophiles, possessing great potential for biocatalytic synthesis. After optimization, 96 mM 5′-CMP was produced within 6 h, and the yield reached nearly 100%[1].

Definition

ChEBI: A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.

Biochem/physiol Actions

Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.

References

[1] Zonglin Li. “Efficient One-Pot Synthesis of Cytidine 5′-Monophosphate Using an Extremophilic Enzyme Cascade System.” Journal of Agricultural and Food Chemistry 68 34 (2020): 9188–9194.

Cytidine 5’-monophosphate synthesis

3616-08-8
63-37-6
Synthesis of Cytidine 5’-monophosphate from CYTIDINE 3':5'-CYCLIC MONOPHOSPHATE

Cytidine 5’-monophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Polyinosinic acid-polycytidylic acid cytidine 5'-phosphate 2',3'-cyclic phosphate CYTIDINE 3'-MONOPHOSPHATE Citicoline sodium

Cytidine 5’-monophosphate Suppliers

Global( 673)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Weitai Biological Pharmaceutical Co.,Ltd.
+8613282012786 sales@weitai-pharmaceutical.com China 61 58
Hangzhou Meiya Pharmaceutical Co Ltd
+86-021-33686691 +8618001850931 sales@meiyapharm.com China 58 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531157085 abby@chuanghaibio.com China 8808 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12809 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5868 58
Hebei Kingfiner Technology Development Co.Ltd 		+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3005 58
airuikechemical co., ltd. 		+86-18353166132 +86-18353166132 sales02@airuikechemical.com China 983 58
Hebei Saisier Technology Co., LTD 		+86-18400010335 +86-18034520335 admin@hbsaisier.cn China 1015 58
BINBO BIOLOGICAL CO.,LTD 		+8618629063126 info@binbobiological.com China 452 58
HebeiShuoshengImportandExportco.,Ltd 		+86-18532138899 +86-18532138899 L18532138899@163.com China 939 58
Supplier Advantage
Hangzhou Weitai Biological Pharmaceutical Co.,Ltd.
58
Hangzhou Meiya Pharmaceutical Co Ltd
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Kingfiner Technology Development Co.Ltd 		58
airuikechemical co., ltd. 		58
Hebei Saisier Technology Co., LTD 		58
BINBO BIOLOGICAL CO.,LTD 		58
HebeiShuoshengImportandExportco.,Ltd 		58

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View Lastest Price from Cytidine 5’-monophosphate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cytidylic acid pictures 2025-04-24 Cytidylic acid
63-37-6
 US $0.00-0.00 / Kg/Drum 1KG 98%min HPLC 1000KG WUHAN FORTUNA CHEMICAL CO., LTD
Cytidine 5'-monophosphate pictures 2025-04-24 Cytidine 5'-monophosphate
63-37-6
 US $0.00 / Kg 1Kg 98% 20 tons Xinxiang Aurora Biotechnology Co.,Ltd.
Cytidine 5-monophosphate（CMP-H） pictures 2025-04-24 Cytidine 5-monophosphate（CMP-H）
63-37-6
 US $0.00-0.00 / kg 1kg 98% 20 MT Hangzhou Meiya Pharmaceutical Co Ltd
  • Cytidylic acid pictures
  • Cytidylic acid
    63-37-6
  • US $0.00-0.00 / Kg/Drum
  • 98%min HPLC
  • WUHAN FORTUNA CHEMICAL CO., LTD

Cytidine 5’-monophosphate Spectrum

Cytidine 5’-monophosphate(63-37-6)13CNMRCytidine 5’-monophosphate(63-37-6)IR1

63-37-6(Cytidine 5’-monophosphate)Related Search:

Polyinosinic acid-polycytidylic acid Tributyl phosphate L-DIHYDROOROTIC ACID NUCLEOSIDE PHOSPHORYLASE BACTERIAL Cytosine
Ethyl 2-(Chlorosulfonyl)acetate Tylosin phosphate Triethyl phosphate Fluorocytosine Ribavirin
AMPHISOL A Hyaluronic acid Citric acid 5-Fluorocytidine 5-Azacytidine
Trisodium phosphate Folic acid Cytidine-5'-triphosphate disodium salt dihydrate

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C-5'-P C-5-P CMP MONOHYDRATE CYTIDINE-5'-MONOPHOSPHATE MONOHYDRATE CYTIDINE-5'-MONOPHOSPHORIC ACID 5'-CYTIDYLIC ACID 5'-CYTIDYLIC ACID MONOHYDRATE 5'-CMP Cytidine Monophosphate and salts Cytidine 5'-monophate CYTIDINE 5'-MONOPHOSPHATE FREE ACIDSIGMA GRADE FRO Cmp:Cytidine-5'-MonophosphateFreeAcid CYTIDINE 5'-MONOPHOSPHATE, FREE ACID (5'-CMP) [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid 5''-CYTIDINE MONOPHOSPHORIC ACID(FREE ACID) Cytidylic acid、CMP Cytidine-5''-monophosphoric acid (and/or unspecified salts) 5'-cytidylate monophosphate Cytidine 3'-(dihydrogen phosphate) 5-CYTIDYLICACID(5-CMP) Cytidine 5’-Monophosphate(CMP) CYTIDINE-5-MONOPHOSPHORIC ACID extrapure 5μ-CMP, 5μ-Cytidylic acid, C-5μ-P Cytidine mono(dihydrogen phosphate) Cytodine monophosphate: (Cytidine 5-monophosphate free acid) Cytidine-5'-monophosphoric acid hydrate,99% ((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl di 5'-CMP 5'-Cytidylic acid C-5'-P CMP 5'-CMP(Cytidine 5'-monophosphate free acid) Cytidine-5'monophosphate(CMP),FREE ACID CMP.H2 cytidylic acid ,5'-cMp cytidine-5Monophophate cmp(nucleotide) cytidine5’-(dihydrogenphosphate) cytidine5’-phosphate cytidine5’-phosphoricacid cytidinemonophosphate CYTIDINE-5'-MONOPHOSPHATE(P) ((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihyd 5'-CMPH2 5'-Cytidylic Acid (500 mg) 5 ' - Cyticline Monophosphoric Acid (Free Acid ) 4-aMino-1-(O5-phosphono-pentofuranosyl)-1H-pyriMidin-2-one Cytidylic acid SynonyMs 5'-cytidylate Monophosphate Cytidine 5'-monophosphate (5'-CMP) Cytidine 5′-monophosphate, synthetic, 99% 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-5-yldihydrogenphosphate Cytidine -5'- Monophosphate（CMP-H） Cytidine 5'-Monophosphate > Cytidylic acid Solution, 100μg/mL -cytidylate monophosphate 5'-CYTIDYLATE MONOPHOSPHATE（CMP） Cytidylic acid USP/EP/BP CYTIDINE-5'-MONOPH0SPHATE 5'-Cytidine monophosphate free acid ((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrog Cytidine-5-Monophosphate (5-CMP) extrapure, 99%