ChemicalBook >> CAS DataBase List >>L-DIHYDROOROTIC ACID
L-DIHYDROOROTIC ACID
- CAS No.
- 5988-19-2
- Chemical Name:
- L-DIHYDROOROTIC ACID
- Synonyms
- DNTPS;Dihydroorotic acid;DIHYDRO-L-OROTIC ACID;L-HYDROOROTIC ACID;(S)-Dihydroorotate;(S)-2,6-dioxohexahydropyrimidine-4-carboxylic acid;DI-H-OROTATE;(S)-di-H-orotate;L-4,5-dihydroorotic;L-DIHYDROOROTIC ACID
- CBNumber:
- CB0386533
- Molecular Formula:
- C5H6N2O4
- Molecular Weight:
- 158.11
- MDL Number:
- MFCD00085339
- MOL File:
- 5988-19-2.mol
- MSDS File:
- SDS
Last updated:2025-04-17 18:22:24
| Melting point | 254-255 °C (dec.)(lit.) |
|---|---|
| Boiling point | 283.16°C (rough estimate) |
| Density | 1.523 |
| refractive index | 1.5090 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Water (Slightly, Heated, Sonicated) |
| pka | 2.82±0.20(Predicted) |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble in water (partly), and dimethyl formamide. |
| InChIKey | UFIVEPVSAGBUSI-REOHCLBHSA-N |
| CAS DataBase Reference | 5988-19-2(CAS DataBase Reference) |
| FDA UNII | 4LPL64ZNA5 |
| NIST Chemistry Reference | Orotic acid, dihydro-, l-(5988-19-2) |
| UNSPSC Code | 12352204 |
| NACRES | NA.83 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
L-DIHYDROOROTIC ACID price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7128 | L-Dihydroorotic acid ≥99% | 5988-19-2 | 1g | $296 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7128 | L-Dihydroorotic acid ≥99% | 5988-19-2 | 5g | $399.6 | 2024-03-01 | Buy |
| Alfa Aesar | H60429 | L-Dihydroorotic acid, 98% | 5988-19-2 | 1g | $156 | 2024-03-01 | Buy |
| Alfa Aesar | H60429 | L-Dihydroorotic acid, 98% | 5988-19-2 | 5g | $613 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7128 | L-Dihydroorotic acid ≥99% | 5988-19-2 | 500mg | $167 | 2024-03-01 | Buy |
L-DIHYDROOROTIC ACID Chemical Properties,Uses,Production
Chemical Properties
White to off-white crystalline powder
Uses
L-Dihydroorotic acid a metabolite.
Definition
ChEBI: (S)-dihydroorotic acid is the (S)-enantiomer of dihydroorotic acid that is an intermediate in the metabolism of pyridine. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a (S)-dihydroorotate. It is an enantiomer of a (R)-dihydroorotic acid.
Biochem/physiol Actions
L-Dihydroorotic acid (DHO) serves as a substrate for dihydroorotate dehydrogenase (DHODH), an enzyme in the de novo synthesis of pyrimidine. Inhibition of DHOH by its inhibitors causes a large accumulation of upstream metabolite DHO and a reduction in the uridine levels. Therefore, DHO and uridine can be used as biomarkers for pyrimidine synthesis for the clinical development of DHOH inhibitors.
IC 50
Microbial Metabolite; Human Endogenous Metabolite
L-DIHYDROOROTIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 313)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12810 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19809 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29859 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
View Lastest Price from L-DIHYDROOROTIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-23 | L-DIHYDROOROTIC ACID
5988-19-2
|
US $99.00-66.00 / kg | 0.001kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2025-04-15 | L-DIHYDROOROTIC ACID
5988-19-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-15 | L-Dihydroorotic acid
5988-19-2
|
US $120.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- L-DIHYDROOROTIC ACID
5988-19-2
- US $99.00-66.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- L-DIHYDROOROTIC ACID
5988-19-2
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- L-Dihydroorotic acid
5988-19-2
- US $120.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
5988-19-2(L-DIHYDROOROTIC ACID)Related Search:
UDP SODIUM SALT
URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
2'-Deoxyuridine
Cytidine-5'-diphosphate disodium salt
Inosine
CTP xsodium
ATP disodium salt
Uridine-5'-diphosphate disodium salt
Orotic acid
Sodium phosphate tribasic dodecahydrate
1of4
L-DIHYDROOROTIC ACID
(S)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
L-4,5-Dihydroorotic acid~(S)-(+)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
(S)-(+)-HYDROOROTIC ACID
(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid
L-4,5-dihydroorotic acid
(S)-4,5-dihydroorotate
(S)-4,5-dihydroorotic acid
(S)-4-pyrimidinecarboxylic acid
(S)-di-H-orotate
4,5-dihydro-L-orotate
DI-H-OROTATE
L-4,5-dihydroorotate
4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-, (4S)-
L-4,5-dihydroorotic
Adenosine-5-triphosphoric acid Na2
Adenosine-5'-diphosphoric acid Na2
Deoxyribonucein acid(fish sperm)
Guanosine-5-diphosphate disodiun
Guanosine-5-monophosphate disodiun
Guanosine-5'-triphosphate disodiun
t-Ribonuclein acid,yeast
4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-
2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid, L-Hydroorotic acid, Dihydro-L-orotic acid
(4S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid
(6S)-Hexahydro-2,4-dioxopyrimidine-6β-carboxylic acid
(S)-Dihydroorotic acid
Hexahydro-2,6-dioxopyrimidine-4α-carboxylic acid
Inosine-5-triphosphate trisodium
Ribonuclein acid,yeast
Deoxyribonucleoside- 5′-triphosphate
(4S)-2,6-dioxo-1,3-diazinane-4-carboxylate
L-5,6-Dihydroorotic acid
L-DIHYDROOROTIC ACID USP/EP/BP
(S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid,L-4,5-Dihydroorotic acid~(S)-(+)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid,L-Dihydroorotic acid,L-Dihydroorotic Acid
L-HYDROOROTIC ACID
DIHYDRO-L-OROTIC ACID
(S)-Dihydroorotate
(S)-2,6-dioxohexahydropyrimidine-4-carboxylic acid
DNTPS
Dihydroorotic acid
(S)-dihydrooroticaci
L-4, 5-dihydrowhey acid
L-DihydrooroticacidL-Dihydrooroticacid
Cytidine-5-phosphate disodium salt (CMP)
Guanosine Phosphate Disodium Salt (GMP)
L-Dihydroorotic acid, 10 mM in DMSO
L -Dihydroorotic acid
5988-19-2
BioChemical
Nucleotide
Metabolomics
Metabolites and Cofactors on the Metabolic Pathways Chart
Metabolic Pathways
Heterocycles
Miscellaneous Biochemicals
Amino Acid Derivatives