2-Pyrimidinamine, N-(1-methylethyl)- (9CI)
- CAS No.
- 4214-72-6
- Chemical Name:
- 2-Pyrimidinamine, N-(1-methylethyl)- (9CI)
- Synonyms
- Isaxonine;2-(Isopropylamino)pyrimidine;N-Isopropylpyrimidin-2-amine;N-Isopropyl-2-pyrimidinamine;2-(N-isopropylamino)pyrimidine;isopropyl(pyrimidin-2-yl)amine;N-(Isopropylamino)-2-pyrimidine;2-Pyrimidinamine, N-(1-methylethyl)-;N-Isopropylpyrimidin-2-amine , Isaxonine;2-Pyrimidinamine, N-(1-methylethyl)- (9CI)
- CBNumber:
- CB31081355
- Molecular Formula:
- C7H11N3
- Molecular Weight:
- 137.18
- MDL Number:
- MFCD00867809
- MOL File:
- 4214-72-6.mol
- MSDS File:
- SDS
Melting point | 27-28℃ |
---|---|
Boiling point | 229℃ |
Density | 1.065 |
Flash point | 93℃ |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Colourless Semi-Solid |
FDA UNII | 883G6DMT63 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
2-Pyrimidinamine, N-(1-methylethyl)- (9CI) price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | I900670 | Isaxonine | 4214-72-6 | 100mg | $145 | 2021-12-16 | Buy |
TRC | I900670 | Isaxonine | 4214-72-6 | 1g | $715 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0303805 | 2-(ISOPROPYLAMINO)PYRIMIDINE 95.00% | 4214-72-6 | 5MG | $503.29 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 46951 | Isaxonine | 4214-72-6 | 1g | $1460 | 2021-12-16 | Buy |
Biosynth Carbosynth | FI63880 | Isopropyl-pyrimidin-2-yl-amine | 4214-72-6 | 500mg | $200 | 2021-12-16 | Buy |
2-Pyrimidinamine, N-(1-methylethyl)- (9CI) Chemical Properties,Uses,Production
Originator
Nerfactor,Ipsen,France,1981
Uses
Isaxonine is a neurotropic agent. Isaxonine prevents synaptic remodeling by suppression of the redundant nerve endings from additional axons. Isaxonine is transformed by cytochrome P 450 into reactive metabolites that lead to immunoallergic hepatitis in man.
Definition
ChEBI: Isaxonine is an aminopyrimidine.
Manufacturing Process
6 liters of ethanol and 685 g (5 mold of 2-isopropylamino pyrimidine were added to a 10 liter reactor and stirred. To the solution were added 600 g (5.2 mols) of phosphoric acid and the mixture was boiled under reflux for one hour. There was obtained a dark green solution which was treated with 30 g of carbon black. After separation and crystallization while stirring overnight, the crystallized product was separated, washed with ethanol and dried at 50°C. There was obtained 1,027 g (87% yield) of a white powder melting at 125°C. The analysis of the compound showed a good correspondence with the formula C7H14O4N3P.
brand name
Nerfactor;Verfactor.
Therapeutic Function
Neurotropic
World Health Organization (WHO)
Isaxonine phosphate was introduced in 1981 and marketed exclusively in France for the treatment of peripheral neuropathy. In January 1983 indications for use were restricted following its association with cases of toxic hepatitis. It was subsequently withdrawn in June 1983.
2-Pyrimidinamine, N-(1-methylethyl)- (9CI) Preparation Products And Raw materials
2-Pyrimidinamine, N-(1-methylethyl)- (9CI) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3002 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42959 | 64 |
Amber MolTech LLC | 086-010-62176588 | amber@jyamber.com | China | 10152 | 56 |
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19918 | 55 |
MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4930 | 55 |
Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28817 | 58 |
Hebei Beckman Biotechnology Co., Ltd. | 15961617865 15961617865 | 2245485247@qq.com | China | 2330 | 58 |
Qi Qi hang Biotechnology Co., Ltd. | 18151111370 | 1046215251@qq.com | China | 6838 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
View Lastest Price from 2-Pyrimidinamine, N-(1-methylethyl)- (9CI) manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-11 | 2-(N-isopropylamino)pyrimidine
4214-72-6
|
US $20.00-100.00 / KG | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd |
- 2-(N-isopropylamino)pyrimidine
4214-72-6
- US $20.00-100.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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