ChemicalBook >> CAS DataBase List >>3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE
3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE
- CAS No.
- 180637-89-2
- Chemical Name:
- 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE
- Synonyms
- Eletriptan Impurity 23;(R)5-(2-Benzenesulfonyl-vinyl)-3-(1-methyl-pyrrolidin-2-ylmethyl)-1H-indole;(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole;(R)-5-[(2-phenylsulfonyl)ethenyl]-3-(N-methylpyrrolidine-2-ylmethyl)-1H-indole;3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE;(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole;3-[[(2R)-1-Methyl-2-pyrrolidinyl]Methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole;1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-
- CBNumber:
- CB31476489
- Molecular Formula:
- C22H24N2O2S
- Molecular Weight:
- 380.5
- MDL Number:
- MFCD09751002
- MOL File:
- 180637-89-2.mol
- MSDS File:
- SDS
Last updated:2023-05-15 10:43:33
Boiling point | 617.7±55.0 °C(Predicted) |
---|---|
Density | 1.263 |
solubility | soluble in Dichloromethane, Dimethylformamide, Methanol |
pka | 16.92±0.30(Predicted) |
FDA UNII | FEU571D9TF |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS08,GHS07 |
---|---|
Signal word | Danger |
Hazard statements | H302-H317-H318-H373 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P280-P305+P351+P338-P310-P260-P314-P501 |
3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Biosynth Carbosynth | FB18184 | R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole | 180637-89-2 | 2mg | $110 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB18184 | R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole | 180637-89-2 | 5mg | $199.9 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB18184 | R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole | 180637-89-2 | 10mg | $363.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | APN0000866 | (R)-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-5-[2-(PHENYLSULFONYL)ETHENYL]-1H-INDOLE 95.00% | 180637-89-2 | 5MG | $496.4 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 63079 | R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole | 180637-89-2 | 5mg | $610 | 2021-12-16 | Buy |
3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Chemical Properties,Uses,Production
Chemical Properties
Red Solid
Uses
(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is the free base of (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Hydrobromide (B120725), which is an impurity of Eletriptan (E505000). Eletriptan is a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines (1,2,3). (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is also an intermediate in the synthesis of 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-1-[1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indol-5-yl]-2-(phenylsulfonyl)ethyl]-5-[(1E)-2-(phenylsulfonyl)ethenyl]-1H-indole (M320195).
3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Preparation Products And Raw materials
3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Suppliers
Global( 21)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Mainchem Co., Ltd. | -- | sarah@mainchem.com | China | 6572 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4901 | 55 |
Nanjing crow LuNing pharmaceutical technology co., LTD | 13382066392 | CHINA | 4880 | 58 | |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56086 | 58 |
Guangzhou Dreampharm Biotechnology Co., Ltd. | 020-36607679 17825480238 | 3008233717@qq.com | China | 9919 | 12 |
Jinan blalong chemical co. LTD | 2710913286@.com | 1513643261@qq.com | China | 14253 | 58 |
3-[[(2R)-1-Methyl-2-pyrrolidinyl]Methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole
3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE
(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole
(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole
(R)-5-[(2-phenylsulfonyl)ethenyl]-3-(N-methylpyrrolidine-2-ylmethyl)-1H-indole
Eletriptan Impurity 23
1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-
(R)5-(2-Benzenesulfonyl-vinyl)-3-(1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
180637-89-2
Chiral Reagents
Indole Derivatives
Intermediates & Fine Chemicals
Pharmaceuticals