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ChemicalBook >> CAS DataBase List >> 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE

3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE

3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE price.
  • $110 - $2551
  • Product name: 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE
  • CAS: 180637-89-2
  • MF: C22H24N2O2S
  • MW: 380.5
  • EINECS:
  • MDL Number:MFCD09751002
  • Synonyms:3-[[(2R)-1-Methyl-2-pyrrolidinyl]Methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole;3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE;(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole;(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole;(R)-5-[(2-phenylsulfonyl)ethenyl]-3-(N-methylpyrrolidine-2-ylmethyl)-1H-indole;Eletriptan Impurity 23;1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-;(R)5-(2-Benzenesulfonyl-vinyl)-3-(1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
Price13 Properties Safety Information Description
13 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • Medical Isotopes, Inc.
Package
  • 2mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9474AA
  • Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole
  • Packaging250mg
  • Price$2551
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number180637892
  • Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole
  • Packaging1g
  • Price$1630.72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPN0000866
  • Product description(R)-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-5-[2-(PHENYLSULFONYL)ETHENYL]-1H-INDOLE 95.00%
  • Packaging5MG
  • Price$496.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18184
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging2mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18184
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging5mg
  • Price$199.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18184
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging10mg
  • Price$363.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18184
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging25mg
  • Price$661
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18184
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging50mg
  • Price$1201.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM146599
  • Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95%
  • Packaging1g
  • Price$1828
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11190844
  • Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95+%
  • Packaging1g
  • Price$1940
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number096313
  • Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95+%
  • Packaging250mg
  • Price$1853
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number63079
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging50mg
  • Price$1380
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number63079
  • Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
  • Packaging5mg
  • Price$610
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9474AA (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 250mg $2551 2021-12-16 Buy
Alichem 180637892 (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 1g $1630.72 2021-12-16 Buy
American Custom Chemicals Corporation APN0000866 (R)-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-5-[2-(PHENYLSULFONYL)ETHENYL]-1H-INDOLE 95.00% 5MG $496.4 2021-12-16 Buy
Biosynth Carbosynth FB18184 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 2mg $110 2021-12-16 Buy
Biosynth Carbosynth FB18184 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 5mg $199.9 2021-12-16 Buy
Biosynth Carbosynth FB18184 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 10mg $363.5 2021-12-16 Buy
Biosynth Carbosynth FB18184 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 25mg $661 2021-12-16 Buy
Biosynth Carbosynth FB18184 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 50mg $1201.5 2021-12-16 Buy
Chemenu CM146599 (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95% 1g $1828 2021-12-16 Buy
Crysdot CD11190844 (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95+% 1g $1940 2021-12-16 Buy
Matrix Scientific 096313 (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95+% 250mg $1853 2021-12-16 Buy
Medical Isotopes, Inc. 63079 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 50mg $1380 2021-12-16 Buy
Medical Isotopes, Inc. 63079 R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole 5mg $610 2021-12-16 Buy

Properties

Boiling point :617.7±55.0 °C(Predicted)
Density :1.263
solubility :soluble in Dichloromethane, Dimethylformamide, Methanol
pka :16.92±0.30(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is the free base of (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Hydrobromide (B120725), which is an impurity of Eletriptan (E505000). Eletriptan is a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines (1,2,3). (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is also an intermediate in the synthesis of 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-1-[1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indol-5-yl]-2-(phenylsulfonyl)ethyl]-5-[(1E)-2-(phenylsulfonyl)ethenyl]-1H-indole (M320195).

Suppliers and manufacturers

CONIER CHEM AND PHARMA LIMITED
SIMAGCHEM CORP
Mainchem Co., Ltd. J & K SCIENTIFIC LTD. Chemsky（shanghai）International Co.,Ltd. AN PharmaTech Co Ltd Nanjing crow LuNing pharmaceutical technology co., LTD Shenzhen Polymeri Biochemical Technology Co., Ltd. Guangzhou Dreampharm Biotechnology Co., Ltd. Jinan blalong chemical co. LTD