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TALIPEXOLE

TALIPEXOLE Structure
TALIPEXOLE structure
CAS No.
101626-70-4
Chemical Name:
TALIPEXOLE
Synonyms
Domin;Talipexol;TALIPEXOLE;Talipexolum;Talipexolum [latin];Talipexol [spanish];TALIPEXOLE USP/EP/BP;6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine;6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine;6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
CBNumber:
CB3153213
Molecular Formula:
C10H15N3S
Molecular Weight:
209.31
MDL Number:
MFCD00867565
MOL File:
101626-70-4.mol
MSDS File:
SDS
Last updated:2024-10-28 23:16:16
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TALIPEXOLE Properties

Boiling point 364.6±37.0 °C(Predicted)
Density 1.167±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
pka 7.22±0.20(Predicted)
FDA UNII 7AM2J46Z1Y

TALIPEXOLE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0009175 TALIPEXOLE 95.00% 101626-70-4 5MG $490 2021-12-16 Buy
American Custom Chemicals Corporation API0009175 TALIPEXOLE 95.00% 101626-70-4 10MG $520 2021-12-16 Buy
American Custom Chemicals Corporation API0009175 TALIPEXOLE 95.00% 101626-70-4 50MG $920 2021-12-16 Buy
AvaChem 2567B Talipexole 101626-70-4 1g $2900 2021-12-16 Buy
Crysdot CD31004840 Talipexole 98+% 101626-70-4 5mg $76 2021-12-16 Buy
Product number Packaging Price Buy
API0009175 5MG $490 Buy
API0009175 10MG $520 Buy
API0009175 50MG $920 Buy
2567B 1g $2900 Buy
CD31004840 5mg $76 Buy

TALIPEXOLE Chemical Properties,Uses,Production

Description

Domin was launched in Japan for Parkinson's disease. The compound is readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its antiparkinson activity resides in the fact that talipexole is a selective agonist for presynaptic dopamine D2 receptors with no D1 receptor activity. It is a clonidine-like α2-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most widely used dopamine angonist. Also it is 70 times more potent than bromocriptine and has a more rapid onset of action. In addition to its anti-tremor activity there was a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT3 receptor antagonistic activity. Its metabolites have no biological activity, there was no development of tolerence and its effect could be enhanced by L-dopa.

Originator

Boehringer Ingelheim (Germany)

Definition

ChEBI: 6-prop-2-enyl-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine is an azepine.

brand name

Domin

TALIPEXOLE Preparation Products And Raw materials

Raw materials

Thiourea

Preparation Products

TALIPEXOLE Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32072 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38466 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2123 70
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Alfa Chemistry 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
LGM Pharma 70
MedChemexpress LLC 58
LETOPHARM LIMITED 58

View Lastest Price from TALIPEXOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Talipexole pictures 2024-10-28 Talipexole
101626-70-4
 US $2500.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • Talipexole pictures
  • Talipexole
    101626-70-4
  • US $2500.00-1980.00 / mg
  • TargetMol Chemicals Inc.

101626-70-4(TALIPEXOLE)Related Search:

ARANIDIPINE Bendamustine Donepezil CALYXOL ISO-TALIPEXOLE, DIHYDROCHLORIDE
TALIPEXOLE DIDHYDROCHLORIDE,Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride,talipexole hydrochloride 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE TALIPEXOLE 2-(THIAZOL-4-YL)ETHYLAMINE AMTHAMINE DIHYDROBROMIDE
5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE 2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE

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TALIPEXOLE 5，6，7，8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4，5-d]azepin-2-amine Domin 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine Talipexol Talipexol [spanish] Talipexolum Talipexolum [latin] 6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine TALIPEXOLE USP/EP/BP 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)- 101626-70-4