ChemicalBook >> CAS DataBase List >>4-Fluorophenylmagnesium bromide

4-Fluorophenylmagnesium bromide

4-Fluorophenylmagnesium bromide structure

CAS No.: 352-13-6

Chemical Name:: 4-Fluorophenylmagnesium bromide

Synonyms: 4-flourophenylmagnesium bromide;4-FL;uorophenyL;4-FluorophenylMagnes;magnesium,fluorobenzene,bromide;4-Fluorophenylmagnesium bromide;p-Fluoro-phenylmagnesium bromide;Magnesium 4-fluorophenyl bromide;Magnesium, bromo(4-fluorophenyl)-;4-fluorophenylmagnesiumbromidesol.

CBNumber:: CB3166792

Molecular Formula:: C6H4BrFMg

Molecular Weight:: 199.3

MDL Number:: MFCD00009667

MOL File:: 352-13-6.mol

MSDS File:: SDS

Last updated:2026-10-27 18:05:21

Request For Quotation

4-Fluorophenylmagnesium bromide Properties

Melting point	5 °C
Boiling point	66°C
Density	1.021 g/mL at 25 °C
Flash point	-20 °C
storage temp.	Flammables + water-Freezer (-20°C)e area
form	Liquid
color	Clear yellow to red-brown
Water Solubility	It reacts violently with water.
Sensitive	Air & Moisture Sensitive
BRN	636802
InChI	InChI=1S/C6H4F.BrH.Mg/c7-6-4-2-1-3-5-6;;/h2-5H;1H;/q;;+1/p-1
InChIKey	QYBFFRXNNFXREA-UHFFFAOYSA-M
SMILES	[Mg](C1=CC=C(F)C=C1)Br
CAS DataBase Reference	352-13-6
EPA Substance Registry System	Magnesium, bromo(4-fluorophenyl)- (352-13-6)
UNSPSC Code	12352103
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05,GHS07,GHS08

Signal word

Danger

Hazard statements

H225-H302-H314-H335-H351-H336-H318-H371-H372

Precautionary statements

P233-P240-P241+P242+P243-P264-P270-P271-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P311-P403+P233-P405-P501-P260h-P303+P361+P353-P501a-P210-P260-P280-P305+P351+P338-P370+P378-P403+P235-P261-P310

target organs

Respiratory system

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

F+,C,F

Risk Statements

12-14-22-34-66-67-11-40-37-19

Safety Statements

16-26-36/37/39-43-45-7/8-33-8-7

RIDADR

UN 2924 3/PG 2

WGK Germany

10-21

TSCA

TSCA listed

HazardClass

PackingGroup

HS Code

29319090

Storage Class

3 - Flammable liquids

Hazard Classifications

Acute Tox. 4 Oral
Carc. 2
Eye Dam. 1
Flam. Liq. 2
Skin Corr. 1B
STOT SE 3

REACH Registrations

Active

Limited Quantities

1.0 L (0.3 gallon) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	3
3		2
	W

4-Fluorophenylmagnesium bromide price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	328820	4-Fluorophenylmagnesium bromide solution 1.0?M in THF	352-13-6	4X25ML	$110	2026-04-30	Buy
Sigma-Aldrich	245550	4-Fluorophenylmagnesium bromide solution 2.0M in diethyl ether	352-13-6	100ml	$107	2026-04-30	Buy
Sigma-Aldrich	245550	4-Fluorophenylmagnesium bromide solution 2.0M in diethyl ether	352-13-6	800ml	$379	2026-04-30	Buy
TCI Chemical	F0673	4-Fluorophenylmagnesium Bromide (ca. 19% in Tetrahydrofuran, ca. 1.0mol/L)	352-13-6	250g	$103	2026-04-30	Buy
Synthonix	F31733	4-Fluorophenylmagnesium bromide, 1.0 M in THF	352-13-6	50ml	$85	2026-05-06	Buy

Product number	Packaging	Price	Buy
328820	4X25ML	$110	Buy
245550	100ml	$107	Buy
245550	800ml	$379	Buy
F0673	250g	$103	Buy
F31733	50ml	$85	Buy

4-Fluorophenylmagnesium bromide Chemical Properties, Uses, Production

Chemical Properties

clear yellow to red-brown solution

Uses

4-Fluorophenylmagnesium bromide solution (Grignard reagent) can be used as a reagent in the synthesis of:

Useful key intermediate in the synthesis of paroxetine.
Arylsulfides via cross-coupling reaction with thiols.
4-Arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as androgen receptor antagonists.
Grignard intermediate for preparing aprepitant.

Uses

4-Fluorophenylmagnesium bromide is used as a reagent for the introduction of the 4-Fluorophenyl group.

reaction suitability

reaction type: Grignard Reaction

4-Fluorophenylmagnesium bromide synthesis

Synthesis of 4-Fluorophenylmagnesium bromide from 4-Bromofluorobenzene

4-Fluorophenylmagnesium bromide Preparation Products And Raw materials

Raw materials

Preparation Products

4-Fluorobenzeneboronic acid 4-(4-Fluoro-phenyl)-piperidin-4-ol hydrochloride 1-Fluoro-4-(1-methylethenyl)benzene 2-(4-Fluorophenyl)-pyrrolidine 4-Fluoro-1,1'-biphenyl

Bis-(4-fluoro-phenyl)-phenyl-methanol (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one

1of2

4-Fluorophenylmagnesium bromide Suppliers

Global Suppliers ( 226)

Supplier	Tel	Email	Country	ProdList	Advantage
Lanzhou Hongsheng Fine Chemical Co., Ltd.	15693160370; 15693160393	lzhschemical@163.com	China	58	58
Infinity SCI	400-106-2016 17800804092	admin@infsci.com	China	475	55
Zhejiang Flowchem Biotechnology Co.,Ltd	13213637321	flowcheminnerse@163.com	China	92	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9409	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44567	61
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11772	60

Supplier	Advantage
Lanzhou Hongsheng Fine Chemical Co., Ltd.	58
Infinity SCI	55
Zhejiang Flowchem Biotechnology Co.,Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61
Beijing Ouhe Technology Co., Ltd	60

View Latest Price from 4-Fluorophenylmagnesium bromide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	4-Fluorophenylmagnesium bromide 352-13-6	$1.00	1kg	99%		Career Henan Chemical Co

4-Fluorophenylmagnesium bromide
352-13-6
$1.00
99%
Career Henan Chemical Co

352-13-6 (4-Fluorophenylmagnesium bromide) Related Search:

Ethylmagnesium bromide Benzylmagnesium chloride Butylmagnesium chloride O-TOLYLMAGNESIUM BROMIDE tert-Butylmagnesium chloride

Cyclopentylmagnesium bromide Isopropylmagnesium chloride Isobutylmagnesium bromide 3-Fluorophenylmagnesium bromide 4-Chlorophenylmagnesium bromide

Propylmagnesium chloride Cyclohexylmagnesium chloride 4-Phenoxyphenylmagnesium bromide 4-(N,N-Dimethyl)anilinemagnesium bromide 4-Fluorophenylmagnesium bromide

Phenylmagnesium bromide Diethyl ether 3,4-Difluorophenylmagnesium bromide

1of4

4-FLUOROPHENYLMAGNESIUM BROMIDE, 2M IN DIETHYL ETHER 4-FLUOROPHENYLMAGNESIUM BROMIDE, 2.0M SO LUTION IN DIETHYL ETHER 4-FLUOROPHENYLMAGNESIUM BROMIDE SOL., ~2 .0 M IN DIETHYL ET 4-FLUOROPHENYLMAGNESIUM BROMIDE, 1.0M SO LUTION IN TETRAHYDROFURAN 4-FLUOROPHENYLMAGNESIUM BROMIDE SOL., ~1 M IN THF 4-Fluorophenylmagnesium Bromide 1.0 M In Tetrahydrofuran 4-Fluorophenylmagnesium Bromide 2.0 M In Diethyl Ether 4-FluorophenylMagnesiuM broMide, 1.0 M solution in THF, SpcSeal 4-FluorophenylMagnesiuM broMide, 2.0 M solution in diethyl ether, SpcSeal 4-fluorophenylmagnesiumbromidesol. 4-Fluorophenylmagnesium bromide solution (1.0M THF) 4-fluorine phenyl magnesium bromide 1M solution in tetrahydrofuran 4-Fluorophenylmagnesium bromide, 1.0 M in THF 4-Fluorophenylmagnesium bromide, 1.0 M in 2-MeTHF 4-Fluorophenylmagnesium bromide, 0.8M solution in THF 4-Fluorophenylmagnesium bromide, 2M solution in diethyl ether Magnesium, bromo(4-fluorophenyl)- 4-fluorophenylmagnesium bromide solution 4-Fluorophenylmagnesium bromide0.8M solution in THFAcroSeal§3 4-Fluorophenylmagnesium bromide2M solution in diethyl etherAcroSeal§3 4-Fluorophenylmagnesium bromide, 1M in MeTHF 4-Fluorophenylmagnesium bromide solution 1.0 in THF 4-Fluorophenylmagnesium bromide solution 2.0 in diethyl ether 4-Fluorophenylmagnesium bromide, 2M solution in diethyl ether, AcroSeal 4-Fluorophenylmagnesium bromide, 0.8M solution in THF, AcroSeal 4-FluorophenylMagnesiuM BroMide (ca. 18% in Tetrahydrofuran, ca. 0.9Mol/L) (ca. 18% in Tetrahydrofuran, ca. 0.9Mol/L) 4-FluorophenylMagnesiuM BroMide 4-FluorophenylMagnes 4-FluorophenylMagnesiuM BroMide (ca. 19% in Tetrahydrofuran, ca. 1.0Mol/L) 4-Fluorophenylmagnesium bromide 1M solution in THF 4-FluorophenylMagnesiuM broMide, 0.8 M solution in THF, J&KSeal FluorophenylMagnesiuM broMide soluti 4-FluorophenylMagnesiuM broMide solution 1.0 M in THF 4-FluorophenylMagnesiuM broMide, 2.0 M solution in diethyl ether, J&KSeal 4-Fluorophenylmagnesium bromide solution 2.0M in diethyl ether 4-Fluorophenylmagnesium bromide, 2.0 M solution in 2-MeTHF, J&KSeal 4-Fluorophenylmagnesium bromide solution( 1.0 M solution in THF) 4-FL uorophenyL p-Fluoro-phenylmagnesium bromide magnesium,fluorobenzene,bromide 4-Fluorophenyl Magnesium Bromide 1. M in THF 4-FLUORO PHENYL MAGENSIUM BROMIDE IN THF 4-Fluorophenylmagnesium bromide 1.0 (4-fluorobenzenide)magnesium(1+)bromide Magnesium 4-fluorophenyl bromide 4-Fluorophenylmagnesium bromide, 1.0 M in THF - [F31733] 4-Fluorophenylmagnesium bromide2.0M in diethyl ether/1.0M in THF 4-flourophenylmagnesium bromide 4-Fluorophenylmagnesium bromide 1M 4-Fluorophenylmagnesium bromide in THF 352-13-6 C6H4BrFMg FC6H4MgBr Grignard Reagents FA - FL Alphabetic