ChemicalBook >> CAS DataBase List >>Atropic acid
Atropic acid
- CAS No.
- 492-38-6
- Chemical Name:
- Atropic acid
- Synonyms
- NSC 20987;ATROPIC ACID;Atropic Acid >10029 ATROPIC ACID;2-PHENYLACRYLIC ACID;Cinacalcet ImpurityI;Α-PHENYLACRYLIC ACID;Atropic acid，492-38-6;2-Phenylpropenoic acid;Ipratropium Impurity D
- CBNumber:
- CB3224700
- Molecular Formula:
- C9H8O2
- Molecular Weight:
- 148.16
- MDL Number:
- MFCD00046531
- MOL File:
- 492-38-6.mol
- MSDS File:
- SDS
Last updated:2024-11-19 20:33:22
| Melting point | 106-107° |
|---|---|
| Boiling point | bp ~267° with partial decompn |
| Density | 1.0061 (rough estimate) |
| refractive index | 1.5049 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.86±0.11(Predicted) |
| color | White to Off-White |
| Water Solubility | 1.3g/L(20 ºC) |
| Merck | 14,874 |
| Stability | Light Sensitive |
| InChIKey | ONPJWQSDZCGSQM-UHFFFAOYSA-N |
| CAS DataBase Reference | 492-38-6(CAS DataBase Reference) |
| FDA UNII | TW16UA35S0 |
| NIST Chemistry Reference | Benzeneacetic acid, «alpha»-methylene-(492-38-6) |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-methylene- (492-38-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 29163990 |
Atropic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2390 | Atropic Acid >93.0%(GC) | 492-38-6 | 5g | $55 | 2024-03-01 | Buy |
| TCI Chemical | A2390 | Atropic Acid >93.0%(GC) | 492-38-6 | 25g | $189 | 2024-03-01 | Buy |
| TRC | A793850 | Atropic Acid | 492-38-6 | 100mg | $65 | 2021-12-16 | Buy |
| TRC | A793850 | Atropic Acid | 492-38-6 | 250mg | $80 | 2021-12-16 | Buy |
| TRC | A793850 | Atropic Acid | 492-38-6 | 1g | $105 | 2021-12-16 | Buy |
Atropic acid Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid.
Uses
Atropic acid is an Impurity of Ipratropium bromide and Atropine Sulfate. Atropic acid and β,β-dimethylatropic acid are plant growth regulators.
Preparation
The synthesis of atropic acid involves several steps. Firstly, tropic acid is oxidized with hot KMnO4 to form benzoic acid. Secondly, tropic acid reacted with HBr to produce C9H9O2Br. Thirdly, C9H9O2Br is reacted with alcoholic KOH to yield atropic acid, C9H8O2. Finally, atropic acid is catalytically hydrogenated to form hydratropic acid, C9H10O2.
Reactions
Atropic acid is formed by the dehydration of tropic acid. Hence addition of water to atropic acid gives tropic acid.
Atropic acid, on oxidation yields benzoic acid. The formation of benzoic acid reveals that atropic acid and tropic acid contain atleast one benzene nucleus with a side chain containing carboxylic acid in their structure.
As atropic acid is an unsaturated acid it mean atropic acid may be either structure (I) or (II) .
Hence, the structure (II) is atropic acid which is confirmed by oxidation with KMnO4 to form phenylglyoxal.
Atropic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 290)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| Zhejiang Karry Pharmachem Co., Ltd. | +8613567161161 | info@karrypharma.com | China | 34 | 58 |
| Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 998 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3002 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9206 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Related articles
- The synthesis routes and applications of atropic acid
- Atropic acid has various physiological effects and is synthesized from components such as lithium dibenzylamide.
- Mar 6，2024
- Ipratropium bromide Impurity D
- Ipratropium bromide Impurity D Synonyms: 2-Phenylpropenoic Acid,Ipratropium Bromide Imp. D (EP), Ipratropium Impurity D, Atro....
- Jul 26，2023
View Lastest Price from Atropic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Atropic acid
492-38-6
|
US $29.00-65.00 / mg | 99.56% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Atropic acid
492-38-6
|
US $29.00-65.00 / mg | 99.56% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-07-16 | Atropic acid
492-38-6
|
US $1.00-100.00 / KG | 1KG | 95% | 200000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Atropic acid
492-38-6
- US $29.00-65.00 / mg
- 99.56%
- TargetMol Chemicals Inc.
-
- Atropic acid
492-38-6
- US $29.00-65.00 / mg
- 99.56%
- TargetMol Chemicals Inc.
-
- Atropic acid
492-38-6
- US $1.00-100.00 / KG
- 95%
- Shaanxi Dideu Medichem Co. Ltd
492-38-6(Atropic acid)Related Search:
1of4
2-Phenylpropenoic acid
2-PHENYLPROP-2-ENOIC ACID
2-PHENYLACRYLIC ACID
ALPHA-PHENYLACRYLIC ACID
alpha-Phenylacrylic acid
2-Phenylacrylic acid
2-Phenylprop-2-enoic acid
ATROPIC ACID
2-Propenoic acid, 2-phenyl-
Acrylic acid, 2-phenyl-
alpha-Toluic acid, alpha-methylene-
Benzeneacetic acide, alpha-methylene-
Propenoic acid, 2-phenyl-
α-methylene-α-toluic acid
ATROPIC ACID / 2-PHENYLACRYLIC ACID
10029 ATROPIC ACID
α-Methylenebenzeneacetic acid
2-Phenylprop-2-enoic acid, Atropic acid
2-Phenyl-2-propenoic Acid
NSC 20987
Benzeneacetic acid, a-Methylene-
Benzeneacetic acid, .alpha.-methylene-
Ipratropium bromide Impurity D
Cinacalcet ImpurityI
Ipratropium EP Impurity D
Ipratropium Bromide EP Impurity D (2-Phenyl Acrylic Acid)
Ipratropium Bromide EP Impurity D
2-Phenylacrylic acid 95%
Ipratropium Bromide Impurity 4(Ipratropium EP Impurity D)
Ipratropium Impurity D
Atropic Acid( Alpha-Phenylacrylic Acid )
Atropic Acid >
2-Phenylacrylic acid, 97%, for synthesis
Benzeneacetic acid, α-methylene-
Ipratropium Bromide Impurity 4（Ipratropium Bromide EP Impurity D）
Α-PHENYLACRYLIC ACID
Atropic acid，492-38-6
Benzeneacetic acid, α-methylene-
492-38-6
C9H8O2
CH2CC6H5COOH
Aromatics, Impurities
Pharmaceutical Intermediates